Clinical trials: Nausea
No Disease or Condition is Being Studied
ANI-Guided Fentanyl Infusion During Living Donor Liver Resections
Thу goal of this study was to learn whether intraoperative analgesia nociception monitoring (ANI) could be beneficial during intraoperative monitoring for patients undergoing living donor liver resections.
- Trial name
- NCT06619977
- Testing
- Analgesia nociception monitoring (ANI)
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bogomolets National Medical University
PONV, Propacetamol
The Opioid-sparing Effect and Reduced PONV Using Propacetamol in PCA Among Patients With High Risk of PONV
While Patient-controlled analgesia (PCA) has the advantage of effectively reducing the degree of postoperative pain, it can also affect the patient's outcome by several adverse effects such as postoperative nausea and vomiting…
- Trial name
- NCT02116257
- Testing
- Propacetamol, PCA regimen
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Nausea, Postoperative
Pre-operative 5% Dextrose Infusion & PONV
With this study, we aim to compare the efficacy of pre-operative dextrose-containing fluid infusion with other fluid for the prevention of PONV in middle ear surgeries.
- Trial name
- NCT05947981
- Testing
- Dextrose 5%, normal saline
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain, Nausea
Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects.
- Trial name
- NCT01149616
- Testing
- Dexamethasone 8mg iv x1
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Postoperative Pain, Postoperative Nausea and Vomiting
Surgical Site Infiltration of Exparel vs TAP Block With Exparel in Patients Undergoing Laparotomy Via Midline Incision
This is a randomized-controlled prospective study to be conducted at Danbury Hospital and Norwalk Hospital to compare postoperative opioid consumption and pain scores of patients with suspected or known gynecologic malignancies…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Opioid Use
- Trial name
- NCT03870685
- Testing
- TAP Block, Surgical Site Infiltration, Exparel
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Danbury Hospital
Pain, Postoperative, Postoperative Nausea and Vomiting
Post-tonsillectomy Pain Control in Adults
This is a randomized prospective study to determine the optimal postoperative pain medication regimen for adults (18 years old and older) undergoing tonsillectomy with or without adenoidectomy for chronic tonsillitis and/or…
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Postoperative Hemorrhage, Body Weight Changes
- Trial name
- NCT02358850
- Testing
- Norco (Hydrocodone and Acetaminophen), Percocet (Oxycodone and Acetaminophen), Dilaudid (hydromorphone)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Sore-throat, Nasopharyngeal Pack
Effect of Oropharyngeal Pack Soaked in Ketamine or Magnesium Sulphate on Post Operative Sore Throat After Nasal Surgery
The aim of this study is to compare the effect of ketamine or magnesium sulphate soaked throat pack on the incidence and severity of post operative sore throat as a primary outcome, post operative nausea and vomiting as a…
- Conditions
- Sore-throat, Nasopharyngeal Pack, Nasal Surgery, Nausea and Vomiting, Postoperative
- Trial name
- NCT05714540
- Testing
- Ketamine Hydrochloride ,Magnesium sulphate and saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Cancer, Child
Psychometric Properties of the Chinese Version of PeNAT
Cancer is a leading cause of death for children. Chemotherapy is the most common treatment for cancer. Notwithstanding the improved survival, children with cancer still have to face a significant amount of symptoms associated…
- Conditions
- Cancer, Child, Nausea, Vomiting
- Trial name
- NCT04827108
- Testing
- PeNAT validation
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Healthy Volunteers
Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy Volunteers
This study looks at how to reduce nausea and vomiting in people taking KarXT which is used to treat mental health conditions like schizophrenia.
- Trial name
- NCT07681076
- Testing
- KarXT, Trimethobenzamide, Ondansetron
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Breast Cancer, Malignant Female Reproductive System Neoplasm
Effect of Yoga in Reducing Chemotherapy Induced Nausea and Vomiting
This randomized controlled three arm study compares the effects of a yoga intervention with jacobsons progressive muscle relaxation training and only standard of care in chemotherapy naive cancer patients.
- Conditions
- Breast Cancer, Malignant Female Reproductive System Neoplasm, Lymphomas, Chemotherapy-induced Nausea and Vomiting
- Trial name
- NCT01387841
- Testing
- yoga, Jacobsons PMRT group
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bharath Charitable Cancer Hospital and Institute
Postoperative Nausea and Vomiting
Effect of Remimazolam on Postoperative Nausea and Vomiting
The present trial is to study the effect of low dose remimazolam on postoperative nausea and vomiting (PONV) in patients at risks of PONV (women, postoperative use of opioid, nonsmokers) undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05439057
- Testing
- Remimazolam, Control
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Inje University
Nausea, Vomiting
A Single Dose, 4-Period, 2-Treatment Replicate Design Bioequivalency Study of Granisetron Hydrochloride 1 mg Tablets Under Fasting Conditions
The objective of this study was to assess bioequivalence of a potential generic 1 mg granisetron tablet formulation compared with Roche Laboratories' 1 mg granisetron tablet, Kytril, following a single 1 mg dose, under fasting…
- Trial name
- NCT00618254
- Testing
- Granisetron
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Lidocaine, Dexmedetomidine
Effect of Lidocaine Plus Dexmedetomidine Infusion on PONV
BACKGROUND: Few researches have manifested that intravenous (IV) lidocaine or dexmedetomidine decreased the incidence of postoperative nausea and vomiting (PONV).
- Conditions
- Lidocaine, Dexmedetomidine, Nausea and Vomiting, Postoperative
- Trial name
- NCT03788018
- Testing
- lidocaine and dexmedetomidine IV, saline IV
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xu Siqi
Postoperative Nausea and Vomiting
Food Related Video and the Incidence of Postoperative Nausea and Vomiting
Postoperative nausea/vomiting (PONV) is a common problem following surgery and anesthesia. There are risk factors that increase the incidence of PONV that are related to the patient, to the surgical procedure or to the anesthetic…
- Trial name
- NCT04719910
- Testing
- Visual exposure to taped food preparation, Visual exposure to topics not related to food
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Vomit Aspiration, Anxiety
Preoperative Oral Carbohydrate on Gastric Emptying
The current preoperative fasting guidelines recommend, applying preoperative carbohydrate solution 2 hours before the operation to minimize prolonged fasting time potential negative effects and improve patient comfort.
- Trial name
- NCT06289543
- Testing
- Preoperative carbohydrate solution
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postoperative Nausea and Vomiting
Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting.
Postoperative nausea and vomiting (PONV) are common and continue to be persistent problems following general anesthesia. Intranasal lidocaine has been used for the treatment of migraine.
- Trial name
- NCT04810494
- Testing
- 2% Lidocaine HCl topical solution, 0.9% Sodium chloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Nausea, Vomiting
The Effect on Thirst, Nausea-Vomiting and Comfort Levels of Menthol Lozenge Applied After Extubation
It is reported that approximately 17.5 million people die worldwide each year due to cardiovascular diseases, including ischemic heart disease, cerebrovascular disease and rheumatic heart disease.
- Conditions
- Nausea, Vomiting, Thirst
- Trial name
- NCT04994262
- Testing
- Menthol Lozenge
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Hyperemesis Gravidarum
The Effect of Mint Flavored Chewing Gum on Hyperemesis Gravidarum Nausea Vomiting Severity, Coping With Stress and Anxiety Level in Pregnants With Hyperemesis Gravidarum
In the research planned as a randomized controlled study, the experimental groups will be administered routine hyperemesis gravidarum (HG) treatment as well as chewing mint-flavored gum, while the control group will only receive…
- Trial name
- NCT06266819
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ordu University
Postoperative Nausea and Vomiting, Hospitalism in Children
Effects of Menthol Gum Chewıng on Postoperatıve Nausea, Vomiting, and Length Of Hospital Stay in Children Undergoing Appendectomy: A Randomızed Controlled Trıal
The study was conducted as an experimental study to determine the effect of menthol chewing gum application on postoperative nausea, vomiting and hospital stay in children with appendectomy.
- Trial name
- NCT05679531
- Testing
- intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ruya Naz
Postoperative Nausea and Vomiting, Postoperative Pain
Dexamethasone for Paediatric Adeno-tonsillectomy - A Dose-finding Study
Adeno-tonsillectomy is a commonly performed surgical procedure in children. Main morbidities are postoperative pain, nausea and vomiting, and haemorrhage.
- Trial name
- NCT00403806
- Testing
- dexamethasone, Saline
- Where
- Switzerland
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva