Clinical trials: Neck Cancer
Oral Cancer
Validation of DNA Methylation Biomarkers for Oral Cancer Detection-Follow up Study
This is a follow up study which aims to evaluate the correlation between several methylated genes (potential biomarkers) and oral cancers.
- Trial name
- NCT02902406
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cervical Cancer Screening, Cervical Cancer
Evaluation of Three Strategies Based on Vaginal Self-sampling Kit Send to Home of Unscreened Women for Cervical Cancer
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4 (NCT03856684)
- Testing
- Self-sampling kit sent at home, Self-sampling kit sent at home + SMS reminder, Letter offering a self-sampling kit "on request"+ SMS reminder
- Where
- France
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Thyroid Nodule, Insulin Resistance
Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules
It has been shown that insulin might be involved in the pathogenesis of thyroid growth. Objective To evaluate the impact of IR and metformin use on the volume of benign thyroid nodules (TNs).
- Trial name
- NCT03183752
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Universitário Clementino Fraga Filho
HPV Infections, Precancerous Disease of the Cervix
Primary and Secondary Prevention of Human Papillomavirus (HPV) Disease in China
In a hospital-based multi-center study in China, HPV 16 was found to be the predominant type (72.9%) in cervical cancer, followed by HPV 18(8.0%) which indicated that if the HPV prophylactic vaccine are wisely applied in China…
- Conditions
- HPV Infections, Precancerous Disease of the Cervix, Cervical Cancer, HPV Related Diseases
- Trial name
- NCT01021904
- Testing
- Gardasil (VLP, HPV Quadrivalent prophylactic vaccine)
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Cervical Cancer
Acceptability of Human Papillomavirus (HPV) Self-sampling Tools for Cervical Cancer Prevention
The proposed study aims to increase HPV screening behaviors in Jamaican women by examining the acceptability of HPV Deoxyribonucleic Acid (DNA) self-sampling tools, and to determine the most culturally appropriate and effective…
- Trial name
- NCT03613493
- Testing
- HPV self-sampling kit, Culturally-targeted Fear Appeal Message, Fear Appeal Message
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cervical Cancer
Health Care Decisions for Female Adolescents: The Role of Mothers and Daughters in Decision Making
Preventing cervical cancer is a public health concern. Since 2006 a quadrivalent vaccine for young women nine to twenty six years of age has been available to protect against the human papillomavirus (HPV) and to prevent some…
- Trial name
- NCT00807898
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Louisville
HPV Infection, HPV Vaccine
Two Domestic HPV Vaccines and Imported HPV Vaccines in Women Aged 13-14 Years Study on Immunogenicity
This is a multi-center, open, prospective cohort study that aims to investigate the immunogenicity and immune persistence of two different domestically produced bivalent HPV vaccines compared with an imported HPV vaccine in women…
- Conditions
- HPV Infection, HPV Vaccine, Cervical Cancer Prevention
- Trial name
- NCT06137352
- Testing
- Follow up
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Cervical Cancer
HPV Screening With Triage by HPV Genotyping Versus Visual Inspection With Acetic Acid
Cervical cancer is the leading cause of cancer death among women in sub-Saharan Africa, despite the existence of effective prevention and screening methods.
- Trial name
- NCT05385406
- Testing
- HPV genotyping, Visual inspection after application of acetic acid
- Where
- 2 sites in Cameroon
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Prof. Patrick Petignat
Oral Health Care, Oral Health Behavior Change
Improving Dental Care for Patients With Head and Neck Tumors
This prospective survey study investigates knowledge, attitudes, experiences, and practices related to dental care in patients with head and neck cancer among affected patients and dentists.
- Conditions
- Oral Health Care, Oral Health Behavior Change, Head & Neck Cancer, Dentist's Role
- Trial name
- OncoDent (NCT07328347)
- Testing
- Educational material,
- Where
- Germany
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Carcinoma, Glioblastoma
MRinRT: Swansea University and SWWCC Collaboration Study.
The aim of this study is to learn whether using MRI (magnetic resonance imaging) scans to plan radiotherapy is better than using CT (computed tomography) scans alone.
- Conditions
- Carcinoma, Glioblastoma, Radiotherapy, MRI
- Trial name
- MRinRT (NCT07365124)
- Testing
- MRI
- Where
- United Kingdom
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Swansea Bay University Health Board
ASC-US, Human Papilloma Virus
Can B12 and Folate Levels Predict HPV Penetration in Patients With ASCUS?
Non-classified atypical squamous cells (ASCUS) is the most common abnormal cervical cytology (%39). The risk of cervical intraepithelial neoplasia 2-3 is 5% and the risk of carcinoma is around 0.1% after diagnosis.
- Trial name
- NCT03903952
- Testing
- Vitamin B12 and folate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Thyroid Cancer, Thyroid Nodule
Modified Cormack Lehane Scores Evaluated by Laryngoscopy During Awake Versus Under General Anesthesia
Nowadays, 5-step modified Cormack-Lehane scoring (MCL) system is frequently used in the observation of laryngeal structures by direct laryngoscopy.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Adenoma
- Trial name
- NCT03826680
- Testing
- Flexible fiberoptic laryngoscopy, Direct laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Cervix Cancer, Screen HPV-positive
Uniting Trusted Community Messengers to Improve Access to Cervical Cancer Screening in Rural North Carolina
The purpose of this study is to test the feasibility and acceptability of a multi-level, community-engaged intervention to increase access to cervical cancer screening using human papillomavirus (HPV) self-collection (HPVSC)…
- Trial name
- NCT07294066
- Testing
- Human papilloma virus screening
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Esophageal Cancer, Gastric Cancer
Molecular Assessment for Gastro-Esophageal Cancer
The goal of this minimally invasive interventional study is to learn if oncometabolic biomarkers, detected in the exhaled breath and blood can identify early-stage gastro-oesophageal cancer in patient at risk for…
- Conditions
- Esophageal Cancer, Gastric Cancer, Barrett Esophagus
- Trial name
- MAGEC (NCT06346054)
- Testing
- Breath analysis, Blood analysis
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Esophageal Cancer, Gastric Cancer
Molecular Analysis for Gastro-Esophageal Cancer: Multicenter Discrete Choice Experiment
The goal of this survey is to investigate the participants' preference for a specific screening/diagnostic tool to detect and assess gastro-esophageal cancer.
- Trial name
- MAGECmultiDiCE (NCT06346080)
- Testing
- Survey
- Where
- Belgium
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cervical Carcinoma, Human Papillomavirus Infection
Evaluating the Human Papillomavirus Self-Collection Experience in Individuals Who Have Experienced Sexual Trauma
This study explores the human papillomavirus (HPV) self-collection experience among individuals with a history of sexual trauma.
- Trial name
- NCT05458869
- Testing
- HPV Self-Collection, Interview, Survey Administration
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
HPV - Anogenital Human Papilloma Virus Infection
Screening for Cervical Intraepithelial Neoplasia Using Self-collected Menstrual Blood
The purpose of this study is to investigate the feasibility and efficacy of assessing HR-HPV DNA and HPV E6/E7 mRNA via self-collected menstrual blood in a smart menstrual pad.
- Trial name
- NCT03638427
- Testing
- Menstrual Blood Analysis (Menstrual Blood Analysis)
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cervical Cancer
A Review of Cervical Cancer Screening Practices in Women Age >65
The goal of this research study is to examine adherence to national guidelines for cervical cancer screening in women age >65. Patient surveys will provide information about women age >65 current cervical screening practices and…
- Trial name
- NCT06431724
- Testing
- Patient Survey, Provider Survey
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sarasota Memorial Health Care System
Infections, Papillomavirus
Efficacy Study of HPV-16/18 Vaccine (GSK 580299) to Prevent HPV-16 and/or -18 Cervical Infection in Young Healthy Women
The purpose of this phase IIB MedImmune-sponsored study was to evaluate the efficacy of the HPV-16/18 VLP vaccine in the prevention of infection with HPV-16 and/or HPV-18 in adolescent and young adult women.
- Trial name
- NCT00689741
- Testing
- Cervarix
- Volunteers
- 1,113 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Papillomavirus Infection, Cervical Cancer
Primary Cervical Cancer Screening by Self-sampling HPV Test
Cervical cancer seriously threatens women's health and HPV infection is the main cause of cervical cancer. Traditionally, Cervical cancer screening is based on cervical exfoliated cell samples collected by health care provider…
- Conditions
- Human Papillomavirus Infection, Cervical Cancer, Negative For Intraepithelial Lesion Or Malignancy, Atypical Squamous Cells of Undetermined Significance
- Trial name
- PREVENT (NCT05613283)
- Where
- 6 sites in China
- Volunteers
- 17,875 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
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