Clinical trials: Necrotic Mandibular Molars
Necrotic Pulp With Symptomatic Apical Periodontitis
The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.
The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults.
- Trial name
- NCT07623629
- Testing
- root canal treatment
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pain Management
Comparing the Effectiveness of Hyalone and Calcium Hydroxide in Reducing Post-operative Pain and Promoting Periapical Healing.
This protocol presents a randomized clinical trial comparing Hyalone (hyaluronic acid) with calcium hydroxide as intracanal medicaments in mandibular first molars with necrotic pulp and symptomatic apical periodontitis.
- Trial name
- HCPH (NCT07821866)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Post Operative Pain, Necrotic Mandibular Molars
Postoperative Pain and Periapical Tissue Healing
The success of endodontic treatment derives from the complete elimination of microorganisms capable of causing an intraradicular or extra radicular infection.
- Trial name
- NCT06771570
- Testing
- Silver Nanoparticles Irrigation
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Radwa fath Ahmed
Necrotic Mandibular Molars, Apical Periodontitis
Impact of Minimally Invasive Endodontic Treatment on the Prognosis of Mandibular Permanent Molars With Necrotic Pulp and Apical Periodontitis
Statement of the problem: The effectiveness of minimally invasive endodontic treatments in managing necrotic pulp with apical periodontitis remains understudied.
- Trial name
- NCT07762248
- Testing
- Root canal treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Ashraf Abdeen
Necrotic Pulp
Evaluation of Pain Relief and Bacterial Reduction After Using Calcium Hydroxide With Mesoporous Silica Nanoparticles as an Intracanal Medicament in Necrotic Mandibular Molars: A Randomized Controlled Clinical Trial
This study compares how well different root canal medications reduce pain and bacteria after treatment of lower molar teeth with necrotic pulp.
- Trial name
- NCT07327996
- Testing
- Calcium Hydroxide Intracanal medication, mesoporous silica nanoparticles paste, Calcium Hydroxide + mesoporous silica nanoparticles
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pulp Necroses
Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars
The purpose of this study is to compare the efficacy of GentleWave versus EdgePro irrigation in the disinfection of infected root canals of human permanent teeth with necrotic pulp.
- Trial name
- NCT06554366
- Testing
- GentleWave, EdgePro laser irrigation, Irrisafe passive ultrasonic irrigation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Endodontic Treatment
Assessment of Postoperative Pain and Bacterial Load Reduction After Using TruNatomy and ProTaper Next Rotary Systems in Patients With Necrotic Mandibular Molars: A Randomized Clinical Trial
This study aims to assess the effect of rotary instrumentation using ProTaper Next rotary system versus TruNatomy rotary system on postoperative pain and the bacterial load reduction following single visit root canal treatment in…
- Trial name
- NCT04862702
- Testing
- mechanical instrumentation using rotary file system
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Necrosis, Postoperative Pain
Evaluation of Post-operative Pain and Bacterial Load Reduction After Application of Three Intra-canal Medications (Cocoa Husk Versus Calcium Hydroxide With and Without Cocoa) in Necrotic Mandibular First Molar.
The study will aim to evaluate the postoperative pain and bacterial load after application of two intracanal medications in mandibular first molar teeth with necrotic pulp.
- Trial name
- NCT07790796
- Testing
- Root canal treatment with intracanal medication by calcium hydroxide for one week., Root canal treatment with intracanal medication by cocoa husk for one week, Root canal treatment with intracanal medication by calcium hydroxide with cocoa husk for one week.
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Revascularization of Immature Young Permenant Teeth
Compare Between the Effect of CGF and PRF on Revascularization of Immature Roots of the Mandibular Permanent First Molar
in this study investigators do revascularization technique to promote root growth of immature mandibular first permanent molar by using CGF and PRF from blood sample of patients
- Trial name
- NCT07460869
- Testing
- Revascularization/Conservative management
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulp Necrosis
Antibacterial Effect and Postoperative Pain After Triton Irrigation Protocol in Necrotic Mandibular Molar
This randomized clinical study evaluates the antibacterial effectiveness and postoperative pain following root canal irrigation using the Triton irrigation protocol in necrotic mandibular molars.
- Trial name
- NCT07435883
- Testing
- triton irrigation protocol, conventional irrigation group
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- sara hosny mostafa
Bacterial Load Reduction, Postoperative Pain
Evaluation of Postoperative Pain and Bacterial Load After Hyalone or Calcium Hydroxide Medication in Mandibular First Molars
This randomized controlled clinical trial aims to evaluate the effect of Hyalone hydrogel compared with calcium hydroxide as an intracanal medicament on postoperative pain and bacterial load reduction in mandibular first molars…
- Trial name
- HYACAL-ENDO (NCT07775456)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Postoperative Pain
Postoperative Pain After Using Reciprocating Motion With Reciproc Files Versus Adaptive Motion With Twisted File Adaptive
assess the effect of using reciprocating motion with reciproc files versus adaptive motion using twisted file adaptive on postoperative pain after instrumentation of necrotic mandibular molars.
- Trial name
- NCT03338322
- Testing
- Twisted file adaptive, Reciproc
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain
Evaluation of Postoperative Pain and Antimicrobial Efficacy of Selenium Versus Calcium Hydroxide As Intracanal Medication in Mandibular First Molars with Necrotic Pulp and Symptomatic Apical Periodontitis
The main rational behind intracanal medicament is to kill the bacteria inside the root canal and to avert reinfection. In absence of nutrients, the bacteria remains after obturation in root canal may not survive.
- Conditions
- Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain, Antimicrobial Effect
- Trial name
- NCT06804330
- Testing
- root canal treatment and intracanal medicament
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Necrotic Pulp With Symptomatic Apical Periodontitis
Evaluation of the Impact of Different Final Irrigation Activation Modes on Healing of Periapical Lesions Related to Permanent Mandibular First Molars Using CBCT.
The goal of this clinical trial is to learn how different ways of activating the cleaning liquid (irrigation) during endodontic treatment affect healing of infections at the root tip (periapical lesions) in adults aged 20 to 40…
- Trial name
- NCT07589556
- Testing
- root canal treatment
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Necrotic Pulp
Postoperative Pain and Antibacterial Efficacy After Root Canal Irrigation With Curcumin or Sodium Hypochlorite
This study aims to compare the effect of 2% curcumin solution versus 2.5% sodium hypochlorite as irrigating solutions in necrotic mandibular molars in terms of postoperative pain and antibacterial effect.
- Trial name
- NCT04728386
- Testing
- curcumin solution, sodium hypochlorite
- Volunteers
- 38 people
- Sponsor
- Cairo University
Necrotic Pulp
Postoperative Pain Following Treatment of Asymptomatic Necrotic Mandibular Molars in Single Visit Using Wave-one Reciprocating Instruments Versus One-Shape Rotary Instruments
The aim of this study is to evaluate the post treatment pain after instrumentation of root canals with a single file reciprocating (Wave-One Ni Ti file, DENTSPLY Maillefer) or rotary(One Shape, Micro Mega, France) file system in…
- Trial name
- NCT03301259
- Testing
- One-shape rotationary system
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University