Clinical trials: Negative Pressure Therapy
Arthroplasty Complications, Amputation
Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings
Negative pressure dressings are currently widely used in wound management. Their use is gradually being extended to surgical scars.
- Conditions
- Arthroplasty Complications, Amputation, Prosthesis-Related Infections
- Trial name
- BERLYTZ (NCT04520841)
- Testing
- Prevena TM, Dry dressing
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Negative-Pressure Wound Therapy, Edema
Impact of Negative Pressure Wound Therapy on Free Muscle Flaps
Aim of the study is to prove the utility and safety of the negative pressure wound therapy (NPWT) in the postoperative management of free flaps.
- Conditions
- Negative-Pressure Wound Therapy, Edema, Free Flap, Microcirculation
- Trial name
- NCT02526342
- Testing
- V.A.C. UltraTM (KCI®,San Antonio, Texas, USA)
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ulf Dornseifer, MD
to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Children with neuromuscular disorders such as cerebral palsy, children with kyphosis and post-traumatic scoliosis have higher infection rates after scoliosis surgery than healthy children who undergo scoliosis surgery.
- Trial name
- NPWT (NCT02790385)
- Testing
- Negative Pressure Wound Therapy, Standard Gauze Treatment
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Ulcer, Venous Ulcer
Efficacy of PICO Single-use System in Chronic Ulcers
A clinical trial will be carried out comparing the efficacy of PICO system based on negative pressure therapy (NPT) in adults with chronic ulcers compared to conventional treatments.
- Conditions
- Chronic Ulcer, Venous Ulcer, Diabetic Foot Ulcer, Pressure Injury
- Trial name
- NCT05877378
- Testing
- Single-use negative pressure therapy (PICO)
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Obesity, Surgical Site Infections
Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery
The investigators aim to show that single use negative pressure dressings can decrease the rate of wound complications in obese women (BMI > 40 kg/m2) undergoing cesarean delivery at a tertiary medical center by randomizing women…
- Conditions
- Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
- Trial name
- NCT02799667
- Testing
- Standard Dressing, Negative Pressure Wound Therapy Dressing
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Surgical Wound Infection, Cesarean Section
Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial
The Prophylactic Negative Pressure Wound Therapy in Obese Women at Cesarean Trial is a large pragmatic multi-center randomized clinical trial designed to evaluate the effectiveness, safety and cost-effectiveness of prophylactic…
- Trial name
- Prevena-C (NCT03009110)
- Testing
- Prophylactic NPWT, Standard Dressing
- Where
- 6 sites in United States
- Volunteers
- 1,624 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obstructive Apnea, Sleep Apnea Syndrome, Obstructive
Pilot Study of Negative Pressure Neck Therapy (NPNT)
Obstructive sleep apnea (OSA) is a serious, chronic sleep-related breathing disease in which the upper airway repeatedly collapses during sleep, leading to intermittent oxygen deprivation.
- Conditions
- Obstructive Apnea, Sleep Apnea Syndrome, Obstructive, Sleep Disorder (Disorder)
- Trial name
- NCT07301567
- Testing
- Negative Pressure Neck Therapy (NPNT)
- Where
- 2 sites in Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Wound Healing
Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work.
- Trial name
- NCT00952120
- Testing
- GSUC, VAC
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Mastectomy; Lymphedema
Endermologie Versus Negative Pressure Therapy on Postmastectomy Lymphedema
Statement of the problem: The problem will be stated in a questionary form: "Which will be more effective endermologie or negative pressure therapy in reducing limb circumference and volume in postmastectomy lymphedema?".
- Trial name
- NCT05761353
- Testing
- Endermologie, Negative pressure therapy
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Primary Snore, Obstructive Sleep Apnea (Mild and Moderate).
Effects of Oropharyngeal Exercises on Patients With Primary Snore, Mild and Moderate Obstructive
Randomized study of patients with primary snore, mild and moderate obstructive sleep apnea. Protocol include 40 patients randomized to oropharyngeal exercise or use of nasal dilator, breathing exercise and nasal lavage.
- Trial name
- EOE (NCT01636856)
- Testing
- Oropharyngeal exercises, Respiratory exercises, nasal dilator, nasal lavage
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Scarring
Prospective Observation of Wound Healing With Prevena Incision Management System
This study aims to assess the quality of wound healing in abdominal scars with and without the Prevena Incision Management System.
- Trial name
- NCT01704924
- Testing
- Prevena, Standard of Care Dressing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Infection, Drainage
Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA
Wound complications and surgical site infections following revision total joint arthroplasty result in significant morbidity and cost.
- Trial name
- NCT03321799
- Testing
- Negative Pressure Wound Therapy (NPWT), Sterile Antimicrobial Dressings
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Lipedema, Secondary Lymphedema
Complete Decongestive Therapy With Negative Pressure for Lipedema and Lymphedema Therapy
This study is designed to investigate the therapy outcomes from routine physical therapy in persons with lipedema and secondary limb lymphedema.
- Trial name
- NCT03634462
- Testing
- CDT with graded negative pressure
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Negative-pressure Wound Therapy, Morbid Obesity
Prophylactic Post-Cesarean Incisional Negative-pressure Wound Therapy in Morbidly Obese Patients
To evaluate the effectiveness of negative-pressure wound therapy in decreasing wound complications in morbidly obese patients (BMI greater than of equal to 40) at Albany Medical Center Hospital.
- Conditions
- Negative-pressure Wound Therapy, Morbid Obesity, Cesarean Section, Wound Infection
- Trial name
- NCT02901613
- Testing
- Negative-pressure wound therapy
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Fistula, Abdominal Injury
Pilot Study Evaluating the Safety and Efficacy of a Patient-Specific Enteroatmospheric Fistula Isolation and Management Device Independent of Negative Pressure Wound Therapy
This study aims to assess the efficacy of a custom fitted device designed to isolate enteroatmospheric fistulas effluent independent of negative pressure wound therapy and to evaluate the effects on the device related to dressing…
- Conditions
- Fistula, Abdominal Injury, Negative Pressure Wound Therapy
- Trial name
- NCT04978090
- Testing
- 3D printed EAF management device
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Andrew Bernard
Root Canal Infection
Effect of Apical Negative Pressure Irrigation System at Cleaning Lateral Canals and Reduction of Periapical Lesions After Endodontic Therapy
The aim of the present study is to assess with PA x-rays and CBCT scans the volumetric changes in periapical radiolucencies in endodontically treated teeth 1 year after endodontic treatment and evaluate how well the lateral…
- Trial name
- NCT03384004
- Testing
- Irrigation Technique 1, Irrigation Technique 2
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KaVo Kerr
Edema, Postoperative Pain
Negative Pressure Wound Therapy in Oral Surgery
Inflammatory complications following the surgical removal of third molars remain a common and unavoidable challenge. These complications significantly impact patients' quality of life, prompting the development of numerous…
- Conditions
- Edema, Postoperative Pain, Postoperative Complications
- Trial name
- NCT06758258
- Testing
- Negative Pressure Wound Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Sleep Apnea, Obstructive
Prescision Medicine in Obstructive Sleep Apnea, Cardiovascular and Cerebrovascular Disease: AI Electrocardiogram Patch Does it All
Obstructive Sleep apnea(OSA) is a disease with multiple causes, and treatments are very diverse. Patients and doctors have a lot of choices.
- Trial name
- NCT05566860
- Testing
- Positional Therapy, Intraoral Negative Pressure Therapy, Oral Appliances
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital