Clinical trials: Negative Symptoms With Primary Psychotic Disorder
Schizophrenia, Depression
Validating Reward-related Biomarkers (RTOC)
Deficits or abnormalities in reward processing are present in a number of psychiatric disorders. The overarching objective of the study is to conduct initial validation work towards optimising three experimental tasks - which…
- Conditions
- Schizophrenia, Depression, Motivation, Anhedonia, Physical
- Trial name
- RTOC (NCT04024371)
- Testing
- Self-rating Questionnaires, Measures of Reward processing/reinforcement learning, Additional Schizophrenia-specific Questionnaires and Interviews
- Where
- 4 sites in Germany, Greece and 2 more
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Psychosis, Negative Symptoms With Primary Psychotic Disorder
Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
Antipsychotics affects the brain's dopamine system, and the drugs reduce delusions, hallucinations, and disorganized thinking, which are cardinal symptoms of psychotic disorders. However, negative symptoms e.g.
- Trial name
- AMEND (NCT04789915)
- Testing
- Memantine
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bjorn H. Ebdrup