Clinical trials: Neglect
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Hookworm Infection, Hookworm Disease
Safety and Immunogenicity Study of Na-GST-1 With or Without CpG
Na-GST-1 is a protein expressed during the adult stage of the hookworm life cycle that is thought to play a role in the parasite's degradation of host hemoglobin for use as an energy source.
- Trial name
- NCT02143518
- Testing
- Na-GST-1/Alhydrogel®, CpG 10104
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Child Abuse
Chatbot Facilitated Education on Child and Adolescent Abuse
The study aims to evaluate the effectiveness of chatbot-facilitated education (CFE) in assisting nursing personnel to prevent child and adolescent abuse and neglect (CAN). The main questions it aims to answer are: 1.
- Trial name
- NCT06167031
- Testing
- chatbot facilitated teaching, lecture-based teaching
- Where
- Taiwan
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University
Child Abuse
Evaluation of the Healthy Families Alaska Program
This study will assess the effectiveness of early home visitation by a professional in preventing child maltreatment, promoting healthy family functioning, and promoting child health and development.
- Trial name
- NCT00216710
- Testing
- Home Visiting
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Family
Validation and Reliability of the Parents Assessment of Protective Factors Survey
Neglect and abuse, which have a devastating effect on children, can be prevented with community-based education programs aimed at strengthening families.
- Trial name
- NCT05066295
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dementia, Elder Abuse
Technology-Based Intervention Pilot Testing
This research project has three main goals: (1) To create a new screening tool that helps primary care doctors spot signs of neglect in older adults with dementia.
- Conditions
- Dementia, Elder Abuse, Elder Neglect
- Trial name
- SIRENS (NCT07146581)
- Testing
- SIRENS
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Segmental Exclusion Syndrome, Complex Regional Pain Syndrome (CRPS)
Peripersonal Space Representation in Upper Limb Segmental Exclusion
This study aims to evaluate the representation of action peripersonal space (PPS) in subjects suffering from unilateral segmental exclusion syndrome of the upper limb compared to healthy control subjects.
- Conditions
- Segmental Exclusion Syndrome, Complex Regional Pain Syndrome (CRPS), Upper Limb Neglect (Peripheral)
- Trial name
- NCT07349173
- Testing
- Reachability Judgment Task in VR.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Healthy
Safety, Tolerability and PK of Single and Multiple Doses of Oxantel Pamoate Tablets
The goal of this clinical trial is to evaluate the safety, tolerability and pharmacokinetics of oxantel pamoate tablet after administration of a single and multiple dose in healthy male and female adult volunteers.
- Trial name
- HELP-OXA (NCT06606860)
- Testing
- Oxantel Pamoate
- Where
- Tanzania
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Visual Neglect
Computerised Assessment of Visual Neglect Symptoms in Peripersonal Space
Healthy subjects will undergo cathodal stimulation of the right posterior parietal Cortex (PPC) and assessment of neglect-like symptoms in the encircling monitor system (EMS) as well as in a standard clinical test (Test Battery…
- Trial name
- KMS-Neglect 2 (NCT01740544)
- Testing
- Cathodal tDCS
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Child Abuse, Child Neglect
Educational Program's Impact on Nursing Students' Knowledge and Awareness of Child Abuse and Neglect
Detecting and determining child abuse and neglect can be quite challenging and largely depends on the knowledge and skills of healthcare professionals.
- Trial name
- NCT05925387
- Testing
- CANAP Education
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Child Abuse, Child Neglect
"Sentinella": Registry and Training for Child Protection
The "Sentinella" project aims to improve the early recognition and prevention of child maltreatment by creating a digital registry and education network for healthcare professionals.
- Conditions
- Child Abuse, Child Neglect, Child Maltreatment
- Trial name
- Sentinella (NCT07250074)
- Testing
- Integrated Digital Registry and Education Intervention
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Buzzi Children's Hospital
Hemispatial Neglect
Rehabilitating Unilateral Neglect Using Spatial Working Memory Training
Purpose: Stroke is a common cause of death and disability in Canada. Injury to the right hemisphere of the brain and the parietal cortex in particular, is common and results in a disorder known as 'neglect' in 40% to 95% of…
- Trial name
- NCT02608190
- Testing
- Working memory training
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Healthy Adolescents in School-based Population, Emotional Neglect
Recognizing Emotional Neglect and Help-Seeking Intention Among Adolescents in Brussels
The goal of this study is to find out how well adolescents in Dutch-speaking secondary schools in Brussels can recognize emotional neglect, and how this relates to their intention to seek help. The main research questions are: 1.
- Conditions
- Healthy Adolescents in School-based Population, Emotional Neglect, Help-Seeking Behavior
- Trial name
- NCT07365891
- Testing
- Emotional neglect vignettes
- Where
- Belgium
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Adverse Childhood Experiences
Building Resilient Families
Prior research suggests that it is possible to improve health outcomes in children with ACEs through multi-component interventions.
- Trial name
- NCT05388864
- Testing
- Three-Tier Model
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Life Change Events, Loneliness
Me and the Others: Expectations and Evaluation of Social Relationships
Chronic and pervasive loneliness has been identified as an important factor in the relationship between adverse childhood experiences (ACE) (e.g. abuse and neglect) and mental disorders.
- Trial name
- NCT03764566
- Testing
- Questionnaires
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Substance-Related Disorders, Depression
Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes
The investigators propose a Hybrid Type 1 effectiveness-implementation quasi-experimental trial. Participants are drawn from two different communities contemporaneously.
- Conditions
- Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse
- Trial name
- NCT04637581
- Testing
- Wraparound
- Where
- 4 sites in United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Trypanosomiasis, Trypanosomiasis, African
Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158
This study is aimed at assessing the tolerability and pharmacokinetic parameters of SCYX-7158 in healthy volunteers. In animal models of both acute and chronic experimental Trypanosomiasis infections, SCYX-7158 shows highly…
- Conditions
- Trypanosomiasis, Trypanosomiasis, African, Protozoan Infections, Parasitic Diseases
- Trial name
- NCT01533961
- Testing
- SCYX-7158
- Where
- 2 sites in France
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Drugs for Neglected Diseases
Healthy Volunteers
First in Man Clinical Trial of Emodepside (BAY 44-4400)
This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers.
- Trial name
- NCT02661178
- Testing
- emodepside (BAY 44-4400)
- Where
- United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Drugs for Neglected Diseases
Stroke, Cognitive and Attention Disorders and Disturbances
The RenAtt Method for Diagnosing and Treating Attention Problems After Stroke and Brain Injury, Further Validation of RehAtt® DiSTRO Assessment of Cognitive and Visual Function
Stroke is one of the most common long-term disabilities in the world. Despite better access to more effective acute treatment, WHO reports a prediction of almost a doubling of disability-adjusted life-years (DALYs) in 2050.
- Conditions
- Stroke, Cognitive and Attention Disorders and Disturbances, Digital Health, Screening Strategy
- Trial name
- NCT07762274
- Testing
- Oxford Cognitive Screen
- Where
- 3 sites in Italy, Sweden and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University