Clinical trials: Neglected Diseases
Senior Abuse
The Impact of Social Phone Calls With Isolated Older Adults Receiving Protective Services for Abuse, Neglect and/or Exploitation
The purpose of this study is to see the the impact of social visits, through weekly phones calls, on quality of life outcomes of depression, anxiety, loneliness, isolation and self-rated health for older adults visited by Adult…
- Trial name
- NCT05026762
- Testing
- Treatment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cerebral Small Vessel Disease
The Impact of Excessive Dietary Sodium on Brain Health
Sporadic cerebral small vessel disease (CSVD) is not only the most common subtype of vascular dementia, in recent multi-center study showed that sporadic CSVD harbors in a third of Alzheimer's disease (AD) patients in 9 Asian…
- Trial name
- NCT05374005
- Where
- Hong Kong
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke
An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation
The aim of this phase is to examine the feasibility and acceptability of the Augmented Reality (AR)-based and electroencephalography (EEG)-based neglect detection and rehabilitation tool.
- Trial name
- NCT04187131
- Testing
- augmented reality
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Pittsburgh
Substance Abuse, Child Abuse
Family-Based Treatment for Parental Substance Abuse and Child Maltreatment
Parental substance abuse is a leading determinant of child maltreatment and, consequently, is often linked with negative clinical outcomes for children, exorbitant financial costs for the child welfare system, and serious social…
- Conditions
- Substance Abuse, Child Abuse, Child Neglect
- Trial name
- NCT01656837
- Testing
- Comprehensive Community Treatment, MST-BSF
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Medical University of South Carolina
Leprosy, Buruli Ulcer
Integrated Mapping of Skin-presenting Neglected Tropical Diseases in Liberia
Appropriate targeting of interventions for neglected tropical diseases (NTDs) that require innovative and intensified disease management (IDM) requires accurate data on the distribution of these diseases within endemic countries.
- Conditions
- Leprosy, Buruli Ulcer, Yaws, Lymphatic Filariases
- Trial name
- NCT03683745
- Where
- Liberia
- Volunteers
- 56,285 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Stroke, Perceptual Disorders
Dynamic Auditory Cueing for Spatial Neglect in Stroke
Spatial neglect is a common condition after stroke and can make it difficult for people to pay attention to one side of space. This problem can negatively affect daily activities and functional independence.
- Conditions
- Stroke, Perceptual Disorders, Spatial Neglect, Spatial Neglect After Stroke
- Trial name
- DAC-SN (NCT07507383)
- Testing
- Dynamic Auditory Cueing, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Gazi University
Stroke
GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy
We aim to determine if targeted high-definition transcranial direct current stimulation (HD-tDCS) can safely correct errors in visual verticality perception in patients after stroke affecting either hemisphere.
- Trial name
- GravNegElect (NCT06747676)
- Testing
- Active: High-Definition transcranial Direct Current Stimulation (HD-tDCS)
- Where
- 2 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Perceptual Disorders, Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation in Traumatic Brain Injury
Randomized Controlled Trial (RCT) aiming at assessing the efficacy of a novel rehabilitation protocol, based on repetitive transcranial magnetic stimulation (r- TMS) in combination with a conventional cognitive treatment (CCT).
- Trial name
- Smart trace (NCT04573413)
- Testing
- Inhibitory repetitive transcranial magnetic stimulation
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Azienda Usl di Bologna
Substance Use Disorders, Pregnancy Related
Substance Use Treatment and Access to Resources (STARS) Project
This study is evaluating a randomized clinical trial and a quasi-experimental observational study combined. Pregnant women with substance abuse issues are referred to the Substance Use Treatment and Recovery (STAR) prenatal…
- Conditions
- Substance Use Disorders, Pregnancy Related, Child Neglect
- Trial name
- NCT04459000
- Testing
- STARS + maternal Attachment Biobehavioral Catchup home visiting model, STARs Only
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- University of Oklahoma
Cutaneous Leishmaniasis, Skin Diseases, Parasitic
Accuracy of a Rapid Diagnostic Test for Cutaneous Leishmaniasis in Morocco
The aim of this study is to estimate the accuracy of CL Detect Rapid Test™ compared to a composite reference standard test (Direct examination of skin smears + PCR test) in patients with clinically suspected Cutaneous…
- Conditions
- Cutaneous Leishmaniasis, Skin Diseases, Parasitic, Neglected Diseases
- Trial name
- NCT02979002
- Where
- 9 sites in Morocco
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- National School of Public Health, Morocco
Vestibular Diseases, Peripheral Neuropathies
Use of a Vibrotactile Sensory Prosthesis in Patients With Postural Imbalance and Spatial Disorientation
The investigators propose to explore the hypothesis that vibrotactile channels for indicating spatial orientation can be exploited as a sensory prosthesis.
- Conditions
- Vestibular Diseases, Peripheral Neuropathies, Proprioceptive Disorders, Hemispatial Neglect
- Trial name
- NCT00146952
- Testing
- Vibrotactile feedback
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke
Clinical Assessment of Spatial Neglect Following Stroke
Spatial neglect (SN) is a common heterogeneous cognitive affliction that predicts poor recovery after a stroke. It is important to identify SN so alliviating actions can be initated.
- Trial name
- NCT04072614
- Where
- Iceland
- Volunteers
- 1,000 people
- Sponsor
- Landspitali University Hospital
Child Abuse, Child Neglect
Fostering Healthy Futures for Teens: An RCT
This study will implement and evaluate a mentoring program designed to promote positive youth development and reduce adverse outcomes among maltreated adolescents with open child welfare cases.
- Conditions
- Child Abuse, Child Neglect, Risk Behavior, Delinquency
- Trial name
- FHF-T (NCT03707366)
- Testing
- FHF-T
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Denver
Neurocysticercosis
Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis
The goal of this clinical trial is to compare the combination albendazole and praziquantel versus albendazole alone in patients affected by neurocysticercosis.
- Trial name
- NeuroSolve (NCT06376396)
- Testing
- albendazole and praziquantel, Albendazole
- Volunteers
- 300 people
- Sponsor
- R-Evolution Worldwide S.r.l. Impresa Sociale
Parent Child Abuse, Domestic Violence
Parenting for Lifelong Health - Thailand
Pilot design: The feasibility pilot of PLH for Young Children in Thailand has a single-site, pre-post design with no control group, with the aims of assessing programme implementation, cultural and contextual relevance, and study…
- Conditions
- Parent Child Abuse, Domestic Violence, Child Behavior Problem, Child Neglect
- Trial name
- NCT03539341
- Testing
- PLH-Thailand parenting programme, Control (care as usual)
- Where
- 4 sites in Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Child Neglect, Internalizing Disorder
Child and Parent-directed Individualized Psychotherapy (CPIP)
With CPIP the investigators opt for a manualized modular psychotherapy designed especially to meet the needs of children with internalizing disorders that suffered or still suffer from emotional or physiological neglect.
- Trial name
- AMIS-II-RCT (NCT05128669)
- Testing
- CPIP, ECS
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
Hemispatial Neglect
Virtual Reality Attention Training in Stroke Patients
Hemispatial neglect is a post-stroke condition in which patients fail to detect stimuli presented on the side of space opposite to the damaged brain hemisphere (contralesional space).
- Trial name
- VRAT (NCT03458611)
- Testing
- Active Intervention
- Where
- 2 sites in Belgium
- Volunteers
- 6 people
- Sponsor
- KU Leuven
Filariasis
PK, Safety and Tolerability of Single and Multiple Doses of Oxfendazole Tablets
The study evaluates the pharmacokinetics (PK), safety and tolerability of oxfendazole, after administration as a tablet formulation in healthy male and female participants.
- Trial name
- HELP-OFZ (NCT04920292)
- Testing
- Oxfendazole
- Where
- Tanzania
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Spatial Neglect
Engaging Mobile Prism Adaptation Treatment at Home
Spatial neglect is a common disorder after stroke which leads to problems with noticing or responding to information from the left side of the body or space.
- Trial name
- EMPATH (NCT05595668)
- Testing
- Prism Adaptation - 15-degree prism goggles, Prism Adaptation - 5-degree prism goggles
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Stroke, Neglect, Hemispatial
Head Mount Display-based Virtual Reality Rehabilitation of Hemispatial Neglect
Head-mounted display based virtual reality rehabilitation for hemispatial neglect.
- Trial name
- NCT03463122
- Testing
- field of regard-focused visual exploration therapy, conventional therapy
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea