Clinical trials: Neglected Diseases
Chronic Kidney Diseases, Diabetes Mellitus
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
Prospective cross-sectional study at the outpatient clinic (OPC) of the Bagamoyo District Hospital (BDH) in Tanzania. Assessment of basic epidemiological data (Point prevalence and risk factors) on CKD with simple clinical…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Hypertension, Tuberculosis
- Trial name
- RenalOne (NCT03458338)
- Testing
- estimated glomerular filtration rate and albuminuria
- Where
- Switzerland
- Volunteers
- 1,006 people
- Sponsor
- University Hospital, Basel, Switzerland
Hemispatial Neglect
The Effectiveness of Transcranial Magnetic Stimulation and Mirror Therapy in Hemispatial Neglect
The aim of this study is to evaluate the effectiveness of continuous Theta Burst Stimulation added to mirror therapy on neglect associated with stroke.
- Trial name
- NCT07228871
- Testing
- Mirror Therapy, cTBS, Cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ankara Etlik City Hospital
Trypanosomiasis, African, Sleeping Sickness
Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense
The ultimate goal of this study is to show that fexinidazole offers an alternative over the existing treatments of Human African trypanosomiasis due to Trypanosoma brucei rhodesiense (r-HAT): melarsoprol in patients with stage 2…
- Conditions
- Trypanosomiasis, African, Sleeping Sickness, Trypanosoma Brucei Rhodesiense; Infection
- Trial name
- NCT03974178
- Testing
- Fexinidazole
- Where
- 2 sites in Malawi, Uganda
- Volunteers
- 45 people
- Sponsor
- Drugs for Neglected Diseases
Spatial Neglect, Cerebral Stroke
The HEP-OKS Study - Hemifield Eye Patching and Optokinetic Stimulation to Treat Hemispatial Neglect in Stroke Patients
Spatial neglect represents one of the major cognitive disorders following stroke. Patients patients fail to be aware of objects or people to their left and orientate instead to their right side.
- Trial name
- NCT01617343
- Testing
- hemifield eye patching (HEP) + optokinetic stimulation (OKS)
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University of Luebeck
Hemispatial Neglect, Hemiplegia
The Effects of Offline Anosognosia For Spatial Neglect on Neglect Rehabilitation
Anosognosia for hemispatial neglect is an intriguing phenomenon characterized by decreased awareness of spatial deficits, common in patients with right hemisphere stroke.
- Conditions
- Hemispatial Neglect, Hemiplegia, Right Hemispheric Stroke, Anosognosia
- Trial name
- NCT05145855
- Testing
- Patient-tailored multimodal neglect rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Gazi University
Behavior, Child, Caries,Dental
Are Dental Neglect and the Siblings Risk Factors in Children
Neglect insidiously affects a child's overall health in all aspects. The aim of this study was to determine whether the presence of siblings caused dental neglect, and whether there was a relationship between dental neglect and…
- Conditions
- Behavior, Child, Caries,Dental, Neglect, Child, Anxiety
- Trial name
- NCT04122508
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Hemispatial Neglect, Stroke
Assessment and Training Visio Spatial Neglect in a Virtual Reality Environment
There is a lack of effective rehabilitation methods for visio-spatial neglect (VSN). By using virtual technology, a new method (virtual reality, VR method) has been created which focuses on stimulating attention networks: top…
- Trial name
- RehAtt (NCT02258789)
- Testing
- VR-method
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Umeå University
Stroke, Unilateral Spatial Neglect
Immersive Virtual Reality Treatment for Unilateral Spatial Neglect
Unilateral Spatial Neglect (USN) is a relatively common neuropsychological syndrome following stroke. It is characterized by difficulties in detecting, orienting and identifying events located in the hemispace contralateral to a…
- Trial name
- NCT06366360
- Testing
- Immersive Virtual Reality Intervention, Conventional rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hopitaux de Saint-Maurice
Stroke, Neurologic Disorder
Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness
The Bioness Integrated Therapy System (BITS) (Bioness Inc. Valencia, CA) Touch Screen is an FDA approved device comprised of an interactive touchscreen and diverse program options to challenge patients through the use of visual…
- Conditions
- Stroke, Neurologic Disorder, Traumatic Brain Injury, Acquired Brain Injury
- Trial name
- NCT04930822
- Testing
- Table Top Visual Intervention, Bioness Integrated Therapy System Visual Intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Gaylord Hospital, Inc
Human African Trypanosomiasis
Assessment of Recombinant HAT-RDT Specificity
Human African trypanosomiasis HAT, or sleeping sickness, is a tropical disease caused mainly by the parasite Trypanosoma brucei gambiense (gHAT).
- Trial name
- NCT05637632
- Where
- Democratic Republic of the Congo
- Volunteers
- 1,504 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Neglect, Hemispatial, Stroke
Immersive Virtual REality for Treatment of Unilateral Spatial NEglect Via Eye-tracking Biofeedback
The purpose of this study is to evaluate the effects of a treatment using virtual reality on the recovery of unilateral spatial neglect.
- Trial name
- IRENE (NCT06264713)
- Testing
- Immersive Virtual Reality
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Opioid-Related Disorders, Stimulant-Related Disorder
Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: PRE-FAIR
Young parents aged 16 to 30, involved in the DHS system for child welfare or self-sufficiency needs are at risk for opioid use disorder and/or methamphetamine use disorder (OUD; MUD).
- Conditions
- Opioid-Related Disorders, Stimulant-Related Disorder, Child Neglect, Mental Health Impairment
- Trial name
- PRE-FAIR (NCT05380440)
- Testing
- Prevention Adaptation of Families Actively Improving Relationships (PRE-FAIR), Standard Case Management and Referral
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Unilateral Spatial Neglect (USN)
Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients
Stroke remains one of the leading causes of mortality and disability worldwide. Between 30% and 40% of patients who have had an acute cerebral hemorrhage, develop unilateral spatial neglect syndrome (USN).
- Trial name
- NCT06802159
- Testing
- Conventional therapy, Eye tracking based therapy, Cognitive therapy
- Where
- 2 sites in Russia
- Volunteers
- 30 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Stroke, Hemispatial Neglect
Transcranial Direct Current Stimulation (tDCS) and Task-Specific Practice for Post-stroke Neglect
The purpose of this study is to test the effects of three different rehabilitation training sessions that combine non-invasive brain stimulation (transcranial direct current stimulation, tDCS) with arm rehabilitation training…
- Trial name
- NCT02892097
- Testing
- tDCS, Repetitive task-specific practice (RTP)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Medical University of South Carolina
Stroke
Effectiveness of Theta Burst Stimulation (TBS) and Voluntary Trunk Rotation for Neglect
This is a double blinded, randomized control trial with a pretest-posttest control and interventional group design. The assessor is blinded to all assessments and evaluations.
- Trial name
- NCT02526238
- Testing
- TMS and trunk rotation
- Where
- Hong Kong
- Volunteers
- 14 people
- Sponsor
- Kowloon Hospital, Hong Kong
Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture
Prism Adaptation Therapy for CRPS Type 1
Complex Regional Pain Syndrome (CRPS) is a clinical condition characterized by pain that arises either without an identifiable triggering factor or with a severity disproportionate to the initiating event.
- Conditions
- Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture, CRPS (Complex Regional Pain Syndromes), Neuropathic Pain
- Trial name
- NCT07370012
- Testing
- The Prism Adaptation Therapy Group, The Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara Etlik City Hospital
Hemispatial Neglect
Virtual Reality Attention Training in Stroke Patients
Hemispatial neglect is a post-stroke condition in which patients fail to detect stimuli presented on the side of space opposite to the damaged brain hemisphere (contralesional space).
- Trial name
- VRAT (NCT03458611)
- Testing
- Active Intervention
- Where
- 2 sites in Belgium
- Volunteers
- 6 people
- Sponsor
- KU Leuven
Visceral Leishmaniasis, Human African Trypanosomiasis
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)
Tropical fevers have been a diagnostic challenge from the antiquity. Nowadays, despite the availability of good diagnostic capacities, undifferentiated febrile illnesses continue to be a thorny problem for travel physicians.
- Conditions
- Visceral Leishmaniasis, Human African Trypanosomiasis, Enteric Fever, Melioidosis
- Trial name
- NCT01766830
- Testing
- rk28 ICT, IT LEISH (rK39), Immunochromatographic HAT test
- Where
- 7 sites in Cambodia, Democratic Republic of the Congo and 2 more
- Volunteers
- 1,927 people
- Sponsor
- University Hospital, Geneva
Type 2 Diabetes (T2DM), Geriatric Syndromes
Using Virtual Reality to Improve Medical Training
As the U.S. population ages, future physicians must be prepared to care for older adults with multiple health conditions and complex needs.
- Conditions
- Type 2 Diabetes (T2DM), Geriatric Syndromes, Disability Hearing, Disability Physical
- Trial name
- NCT07542834
- Testing
- Cinematic Virtual Reality Training, Traditional Didactic Lecture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio University
Stroke, Neglect, Hemispatial
Strategy Training for Individuals With Unilateral Neglect
It is common for individuals after stroke to have a cognitive perceptual impairment called unilateral spatial neglect (neglect).
- Trial name
- NCT06400147
- Testing
- Strategy Training, Attention Control
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Pittsburgh