Clinical trials: Neonatal Death
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neonatal Death, Prematurity
Outcomes Following Early Parenteral Nutrition Use in Preterm Neonates
BACKGROUND An essential part of neonatal care is providing nutrition to ensure that babies grow and develop. Providing this can be difficult in premature babies because their intestines are underdeveloped.
- Trial name
- NCT03767634
- Testing
- Parenteral nutrition
- Where
- United Kingdom
- Volunteers
- 97,507 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Mortality Through Six Months of Age, Vitamin A Deficiency
Community Trial of Newborn Vitamin A Supplementation to Reduce Infant Mortality in Rural Bangladesh
The purpose of this trial is determine whether a 50,000 IU oral dose of vitamin A delivered to newborn infants within the first days of life, reduces six-month infant mortality by at least 15%.
- Trial name
- NCT00128557
- Testing
- vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)
- Where
- Bangladesh
- Volunteers
- 15,937 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Fetal Death, Fetal Anomaly
Antenatal Palliative Care
In France, according to current legislation, termination of pregnancy could be performed without any upper gestational age limit, if there is a strong probability that the fetus will be affected by a particularly severe and…
- Trial name
- SPAN (NCT03795857)
- Testing
- Semi-structured interviews
- Where
- 3 sites in France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Maternal and Perinatal Death Surveillance and Response (MPDSR) Implementation, Maternal Mortality
Accelerating Maternal and Newborn Survival: The AMANI Study
The goal of this cluster randomized controlled trial is to learn if a practice facilitation package (including both audit and feedback and enhanced mentorship) can increase the use of maternal and perinatal death surveillance and…
- Conditions
- Maternal and Perinatal Death Surveillance and Response (MPDSR) Implementation, Maternal Mortality, Neonatal Mortality, Perinatal Mortality
- Trial name
- AMANI (NCT07560839)
- Testing
- Audit and Feedback, Enhanced Mentorship
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Washington
Maternal Death, Newborn Death
Impact of the Safe Childbirth Checklist in Luapula Province of Zambia Province of Zambia
This study would like to determine if the introduction of the Safe Childbirth Checklist and associated mentorship can improve the adherence of skilled birth attendants (SBAs) to the essential practices of childbirth delivery.
- Trial name
- NCT03263182
- Testing
- Introduction of the Safe Childbirth Checklist
- Where
- 4 sites in Zambia
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
Perinatal Death
Evaluation of Enhanced Delivery and Newborn Kit
The evidence is required to assess the effectiveness of enhanced delivery and newborn kits as compared to standard delivery kits in the flood affected districts that can increase the utilization of services and reduce the delays…
- Trial name
- NCT05640063
- Testing
- Enhanced Delivery and Newborn kit
- Where
- Pakistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Long QT Syndrome, Sudden Cardiac Death
Electromechanical Profiling of the Long-QT Syndrome (LQTS)
High-resolution, non-invasive electromechanical mapping in genotyped long-QT syndrome patients and healthy controls at baseline and during smart provocation.
- Conditions
- Long QT Syndrome, Sudden Cardiac Death, Ventricular Tachycardia
- Trial name
- EMLoQ (NCT04074122)
- Testing
- Adenosine and epinephrine, isoprenaline provocation
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Maternal Death, Maternal Morbidity
BetterBirth: A Trial of the WHO Safe Childbirth Checklist Program
The purpose of this study is to measure the impact of a checklist-based childbirth safety program (the WHO Safe Childbirth Checklist Program) on reduction of severe maternal, fetal, and newborn harm in institutional deliveries in…
- Conditions
- Maternal Death, Maternal Morbidity, Stillbirth, Neonatal Death
- Trial name
- BetterBirth (NCT02148952)
- Testing
- WHO Safe Childbirth Checklist Program
- Where
- India
- Volunteers
- 157,689 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Perinatal Mortality, Cause of Neonatal Death
Verbal Autopsy to Assess Early Neonatal Death and Stillbirth
The NICHD Global Network (GN) for Women's and Children's Health Research, a multi-site, international research network, provides a unique infrastructure to implement an expanded perinatal verbal autopsy study using the FIRST…
- Conditions
- Perinatal Mortality, Cause of Neonatal Death, Cause of Stilbirth
- Trial name
- VA (NCT00640055)
- Testing
- Coordinator, Physician-assigned cause of death
- Where
- 4 sites in Guatemala, Pakistan and 2 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Stillbirth, Fetal Death
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Fetal growth restriction during pregnancy represents one of the biggest risk factors for stillbirth (Gardosi et al, 2013), with 'about one in three term, normally formed antepartum stillbirths are related to abnormalities of…
- Conditions
- Stillbirth, Fetal Death, Fetal Growth Retardation, Small for Gestational Age
- Trial name
- OxGRIP (NCT03662178)
- Where
- United Kingdom
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Infant, Small for Gestational Age, Infant, Low Birth Weight
KBTH-GIRHL Healthy Birth Weight Study: A Cross-Section
This study was designed and conducted in an effort to establish a comparison group for the Ghana PrenaBelt Trial (NTC02379728). The Ghana PrenaBelt Trial examined the effect, on birth weight, of a belt-like device to help…
- Conditions
- Infant, Small for Gestational Age, Infant, Low Birth Weight, Pregnancy, Sleep
- Trial name
- KBTH-HBWS (NCT03062228)
- Where
- Ghana
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Vitamin A Deficiency, Maternal Mortality
Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh
The purpose of this trial is to determine whether providing women with a weekly oral supplement of vitamin A, either preformed or as beta-carotene, at a dosage equivalent to a recommended intake from early pregnancy through three…
- Conditions
- Vitamin A Deficiency, Maternal Mortality, Infant Mortality
- Trial name
- NCT00198822
- Testing
- Vitamin A or Beta-Carotene Supplements
- Where
- 3 sites in United States, Bangladesh
- Volunteers
- 59,666 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Early Postpartum and Newborn Care, Maternal Mortality
Post Partum Maternal and Neonatal Intervention Package
Introduction of a community-based intervention package including prevention strategies, early recognition and management of common postpartum \& neonatal problems, as well as prompt referral of high risk/complicated cases through…
- Conditions
- Early Postpartum and Newborn Care, Maternal Mortality, Neonatal Mortality
- Trial name
- NCT01389219
- Testing
- Intervention
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Perinatal Mortality, Stillbirth
Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality
The purpose of this study is to determine whether a daily prenatal supplement of iron plus folic acid or a daily prenatal supplement with multiple vitamins and minerals given to women from their first prenatal visit through…
- Conditions
- Perinatal Mortality, Stillbirth, Neonatal Mortality
- Trial name
- NCT00133744
- Testing
- folic acid, folic acid plus iron, supplements with multiple vitamins and minerals
- Where
- 5 sites in China
- Volunteers
- 18,962 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Maternal Death, Newborn Death
Replicating MamaToto in Rural Tanzania
This study aimed to adapt and implement a district-led, policy-based, low cost Maternal and Newborn Health (MNH) intervention package using the MamaToto process, proven successful in Uganda, in rural Tanzania.
- Trial name
- NCT02506413
- Testing
- MamaToto Package
- Where
- Tanzania
- Volunteers
- 8,323 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Asphyxia Neonatorum
First Breath: Neonatal Resuscitation in Developing Countries
In developing countries, neonatal death from birth asphyxia is a major problem. This study will be conducted in several countries to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared…
- Trial name
- NCT00136708
- Testing
- Neonatal Resuscitation
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 120,009 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Preeclampsia, Preterm Birth
Prediction of Preeclampsia and Other Pregnancy Complications Following Combined Iterative Screening
Preterm birth (PTB), preeclampsia (PE), fetal growth restriction (FGR) and intra-uterine fetal death (IUFD) constitutes the main causes of perinatal morbidity and mortality and are called "Great Obstetrical Syndromes".
- Conditions
- Preeclampsia, Preterm Birth, Fetal Growth Restriction, Intra Uterine Fetal Death
- Trial name
- PREDICTION2 (NCT03067298)
- Where
- Canada
- Volunteers
- 805 people, healthy volunteers welcome
- Sponsor
- Emmanuel Bujold