Clinical trials: Neonatal Mortality
Perinatal Death
Evaluation of Enhanced Delivery and Newborn Kit
The evidence is required to assess the effectiveness of enhanced delivery and newborn kits as compared to standard delivery kits in the flood affected districts that can increase the utilization of services and reduce the delays…
- Trial name
- NCT05640063
- Testing
- Enhanced Delivery and Newborn kit
- Where
- Pakistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Perinatal Mortality, Neonatal Morbidities
Machine Learning From Fetal Flow Waveforms to Predict Adverse Perinatal Outcomes
The aim of this study is to get a proof of concept for using a computational model of fetal haemodynamics, combined with machine learning based on Doppler patterns of the fetal cardiovascular, cerebral and placental flows, to…
- Trial name
- NCT03398551
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Stillbirth, Infant Mortality
Impact of Smoke-free Legislation on Early-life Mortality and Low Birth Weight in England
The purpose of this study is to investigate whether there has been a change in low birth weight and perinatal and infant mortality following the July 2007 introduction of a ban on smoking in public places and workplaces in…
- Conditions
- Stillbirth, Infant Mortality, Sudden Infant Death, Infant, Low Birth Weight
- Trial name
- NCT02039583
- Testing
- Smoke-free legislation
- Where
- United Kingdom
- Volunteers
- 10,291,118 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Neonatal Pneumonia
Risk Factors of Mortality in Neonatal Pneumonia
Neonatal pneumonia, a lower chest infectious disease, is one of the most serious and fatal diseases in young infants.(1) Neonates may catch pneumonia vertically from mother or horizontally from the environment at birth time.
- Trial name
- NCT06599125
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Vitamin A Deficiency
Newborn Vitamin A (VA) Supplementation Pilot Project, Pakistan
Vitamin A is an essential micronutrient for the normal functioning of the visual system, growth and development, immunity and reproduction. Its deficiency causes anemia, growth retardation and xerophthalmia.
- Trial name
- VA (NCT00674089)
- Testing
- Vitamin A
- Where
- Pakistan
- Volunteers
- 7,400 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
High Perinatal Mortality, High Neonatal Mortality
Measuring the Impact of a Mobile Health System to Support Healthy Pregnancies and Improve Newborn Survival
The purpose of this community-based randomized controlled trial is to test whether the mCARE-II intervention package, delivered by the existing Government of Bangladesh community health workforce, will improve neonatal and…
- Conditions
- High Perinatal Mortality, High Neonatal Mortality, Low Antenatal Care Service Utilization, Low Postnatal Care Service Utilization
- Trial name
- mCARE-II (NCT02909179)
- Testing
- mCARE-II
- Where
- Bangladesh
- Volunteers
- 113,539 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sepsis
Zambia Chlorhexidine Application Trial
This will be a cluster-randomized controlled trial to assess whether washing the umbilical cord with a disinfectant (4% chlorhexidine) helps to reduce neonatal deaths in Zambia when compared to the current standard of care, dry…
- Trial name
- ZamCAT (NCT01241318)
- Testing
- Chlorhexidine gluconate (4%), Dry cord care
- Where
- Zambia
- Volunteers
- 77,535 people, healthy volunteers welcome
- Sponsor
- Boston University
Maternal Death, Maternal Morbidity
BetterBirth: A Trial of the WHO Safe Childbirth Checklist Program
The purpose of this study is to measure the impact of a checklist-based childbirth safety program (the WHO Safe Childbirth Checklist Program) on reduction of severe maternal, fetal, and newborn harm in institutional deliveries in…
- Conditions
- Maternal Death, Maternal Morbidity, Stillbirth, Neonatal Death
- Trial name
- BetterBirth (NCT02148952)
- Testing
- WHO Safe Childbirth Checklist Program
- Where
- India
- Volunteers
- 157,689 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Asphyxia Neonatorum
First Breath: Neonatal Resuscitation in Developing Countries
In developing countries, neonatal death from birth asphyxia is a major problem. This study will be conducted in several countries to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared…
- Trial name
- NCT00136708
- Testing
- Neonatal Resuscitation
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 120,009 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Maternal Mortality
Community Based Strategies to Reduce Maternal Mortality in Northern Nigeria
The objective of this cluster randomized controlled trial is to assess the impact of several community-based interventions that address the key factors underlying the high maternal mortality, as well as neonatal mortality and…
- Trial name
- NCT01487707
- Testing
- Voluntary Health Worker (VHW) Program, Safe Birth Kit, Community Folk Media Campaigns
- Where
- Nigeria
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
External Causes of Morbidity and Mortality, Stillbirth
Linking Facility-based Mortality Audits With Community Engagement in Gilgit-Baltistan, Pakistan
Pakistan is one of the countries in South Asia where neonatal mortality rates remain stagnant. Babies born in Pakistan encounter the highest risk of dying; of every 1,000 babies born, 46 die before the end of their first month…
- Conditions
- External Causes of Morbidity and Mortality, Stillbirth, Neonatal Death
- Trial name
- NCT03904706
- Testing
- Audits only, Audits with community feedback
- Where
- Pakistan
- Volunteers
- 1,871 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pregnancy Complications
Operations Research to Improve Newborn Health
This study is designed to look at how operations are carried out in relation to improving the health and survival of newborn babies in India.
- Trial name
- NCT00198887
- Testing
- Operations research
- Where
- India
- Volunteers
- 59,651 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cause of Mortality, Cause of Neonatal Death
Defining Causes of Deaths in South and Southeast Asia
Brief Summary: Mortality data are important in low and middle-income countries to assess the population health status and trends.
- Conditions
- Cause of Mortality, Cause of Neonatal Death, Cause of Child Death, Cause of Maternal Death
- Trial name
- SEACTN-VA (NCT04595656)
- Testing
- verbal autopsy interview
- Where
- 5 sites in Bangladesh, Burma and 3 more
- Volunteers
- 3,413 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Maternal Mortality, Access to Health Care
Project to Use Community Health Workers to Reduce Maternal Deaths
The purpose of this trial is to establish if several interventions will help women in rural Tanzania access health care services during pregnancy and at the time of delivery.
- Trial name
- EWH (NCT03024905)
- Testing
- Village meeting and travel vouchers, Birth kit with misoprostol
- Where
- Tanzania
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
Asphyxia Neonatorum, Neonatal Mortality
Neonatal Resuscitation in Zambia
Asphyxia is a leading cause of neonatal death in Zambia. This study will be conducted in two cities in Zambia to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared to the new World…
- Conditions
- Asphyxia Neonatorum, Neonatal Mortality, Hypoxic Ischemic Encephalopathy
- Trial name
- NCT00097097
- Testing
- Neonatal Resuscitation
- Where
- Zambia
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Sepsis, Pregnancy
Chlorhexidine Vaginal and Infant Wash in Pakistan
Infection is a major health problem during birth in Pakistan. This study will look at the possibility of using a septic wash to help improve health during birth in Karachi, Pakistan.
- Trial name
- NCT00121394
- Testing
- Chlorhexidine vaginal and infant wash
- Where
- Pakistan
- Volunteers
- 5,008 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Child Growth, Diversity of Microbiome
MORDOR II Burkina Faso: Longitudinal Trial
Globally, childhood mortality has shown a promising downward trend in recent years, however, many sub-Saharan countries still have relatively high child mortality rates.
- Conditions
- Child Growth, Diversity of Microbiome, Child Mortality, Resistance Bacterial
- Trial name
- GAMIN (NCT03676751)
- Testing
- Azithromycin
- Where
- Burkina Faso
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy, Neonatal Mortality
Scalable Public Health Empowerment, Research, and Education Sites (SPHERES)
SPHERES is a health service research trial in the Indonesian primary care system designed to improve health system performance using a structured data-driven action model.
- Conditions
- Pregnancy, Neonatal Mortality, Tuberculosis, Hepatitis B
- Trial name
- SPHERES (NCT07126041)
- Testing
- Prescription for Action (SPHERES Model)
- Where
- 2 sites in Indonesia
- Volunteers
- 1,750,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Clinical Research Unit Indonesia
Very Low Birth Weight Infant
Emollient Therapy for Premature Infants in Zimbabwe
The purpose of this study is to assess the efficacy of topical emollient treatments in improving neonatal growth and mortality rates.
- Trial name
- NCT05461404
- Testing
- Topical Emollient Therapy
- Where
- Zimbabwe
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Stanford University