Clinical trials: Neonatal Outcome
Cystic Fibrosis
Improving Adherence and Clinical Outcome in Cystic Fibrosis (CF) Patients
The purpose of this study is to assess the impact of a collaborative active intervention program of a multi-disciplinary team on improving adherence to chronic medications and improve clinical outcomes in CF patients.
- Trial name
- NCT01025258
- Testing
- Frequent Scheduled CF clinic visits, frequent telephone calls to patients pre and post visits to the clinic
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Sheba Medical Center
Nutritional Deficiencies, Phenylketonuria
Follow-up of Adult Phenylketonuria (PKU) Patients
Adult patients with phenylketonuria (PKU) at the age around 40 years belong to the first patients generation with early treatment of the disease.
- Trial name
- NCT01096758
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Friedreich Ataxia, Rare Diseases
Understanding the Natural History Early in the Course or Presentation of Friedreich Ataxia
Multicenter, prospective, observational natural history and outcome measure study of children and young adults with Friedreich ataxia.
- Trial name
- EARLY-FA (NCT06560346)
- Testing
- Geneticlly confirmed disease causing FXN mutatuion, Healthy Control
- Where
- 7 sites in United States, Australia and 3 more
- Volunteers
- healthy volunteers welcome
- Sponsor
- Friedreich's Ataxia Research Alliance
Respiratory Insufficiency Syndrome of Newborn, Breastfeeding Status
Oxytocin Administration Prior Planned Caesarean Section
Spontaneous vaginal delivery of a healthy infant provokes a unique surge in stress hormone concentrations (e.g. AVP (arginine vasopressin) /copeptin) incommensurable with child or adult levels measured in any other situation.
- Trial name
- NCT03693885
- Testing
- Oxytocin challenge test (OCT)
- Where
- 5 sites in Switzerland
- Volunteers
- 1,450 people
- Sponsor
- University of Zurich
Cystic Fibrosis, Diabetes Mellitus Type I
Social Determinants in Chronic Disease in British Columbia
Anyone who practices clinical medicine will understand that socially disadvantaged children will have worse health outcomes, no matter what the underlying condition might be.
- Conditions
- Cystic Fibrosis, Diabetes Mellitus Type I, Chronic Renal Insufficiency
- Trial name
- NCT02203084
- Testing
- Social Determinants Questionnaire
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)
Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes
The thymus gland is a specialized organ in the chest that plays a central role in the adaptive immune system throughout development until puberty. In response to stress, the fetal thymus gland may shrink, or involute.
- Trial name
- TIPS (NCT01975792)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Neonatal Congenital Heart Disease
Magnetic Resonance Imaging (MRI) to Evaluate Brain Injury in Congenital Heart Disease
Infants with congenital heart disease (CHD) requiring surgery frequently have brain injury seen on magnetic resonance imaging (MRI).
- Trial name
- CHD Brain (NCT00932633)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Emory University
Orthognathic Surgical Procedures
Facial Conformation Meshes for Orthognathic Surgery
This study is a retrospective analysis that evaluates the accuracy of 3D soft tissue simulation in bimaxillary orthognathic surgery for Class III dentofacial deformities.
- Trial name
- FEU (NCT06893614)
- Where
- 2 sites in Egypt
- Volunteers
- 13 people
- Sponsor
- Ain Shams University
Neurofibromatosis 2
Reliability of Functional Outcome Measures in Neurofibromatosis 2
Neurofibromatosis 2 (NF2) is a rare inherited condition. Those with NF2 usually present with tumours (schwannomas) in their inner ear, or vestibular organ, with common symptoms including problems with hearing, balance, dizziness…
- Trial name
- NCT03617276
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Infant, Newborn, Maternal Outcome
The Half Swaddling Application on Infant Sleep Routine, Maternal Sleep Quality, Depression
In this prospective controlled study, it was aimed to examine the effects of half swaddling in term infants on infant sleep routine, maternal sleep quality and postpartum depression.
- Trial name
- Half swaddling (NCT06750796)
- Testing
- The Half Swaddling Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tanta University
Angelman Syndrome
Angelman Syndrome Natural History Study-FAST UK
The goal of this study is to conduct a prospective, longitudinal assessment of the natural clinical progression of Angelman syndrome (AS) in children and adults.
- Trial name
- NCT05100810
- Testing
- Natural History Study
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Oxford
Pregnancy Outcome, Gestational Weight Gain
The Effect of Individualized Exercise Guidance on Pregnancy Outcome
A single center, randomized controlled trial was conducted to investigate whether individualized exercise guidance was more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Pregnancy Outcome, Gestational Weight Gain, Mediation, Macrosomia, Fetal
- Trial name
- NCT05760768
- Testing
- Individualized exercise guidance
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Primary Maternal and Neonatal Outcomes; Assisted Reproductive Technology
Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.
The investigators retrospectively analysed the maternal and neonatal outcomes following a single fresh blastocyst transfer and a single warmed blastocyst transfer from procedures performed between 2014 and 2018 in a tertiary…
- Trial name
- NCT04310761
- Testing
- one single blastocyst transfer, both fresh and warmed
- Volunteers
- 4,613 people
- Sponsor
- Istituto Clinico Humanitas
Limb-Girdle Muscular Dystrophy ; Subtypes 2A, 2B, and 2I
Limb-Girdle Video Assessment
The purpose of this study is to develop a new remote-based video assessment outcome measure for Limb-Girdle Muscular Dystrophy (LGMD) trials. The overall objectives for this study are: 1.
- Trial name
- NCT05528757
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Emmes Company, LLC
Psoriatic Arthritis, Psoriasis
Apremilast Pregnancy Exposure Registry
The purpose of the Apremilast Pregnancy Exposure Registry is to monitor planned and unplanned pregnancies exposed to apremilast and to evaluate the safety of this medication relative to specified pregnancy outcomes, and to…
- Trial name
- NCT02775500
- Testing
- apremilast
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Patent Ductus Arteriosus (PDA)
Outcome of Transcatheter Closure of Patent Ductus Arteriosus in Pediatric Cardiology Unit in 3 Years Duration
Transcatheter Closure of Patent Ductus Arteriosus to evaluate the outcome of percutaneous transcatheter closure of patent ductus arteriosus in children
- Trial name
- NCT06634407
- Testing
- transcatheter closure
- Volunteers
- 90 people
- Sponsor
- Assiut University
Delayed Cord Clamping, Hemoglobin
The Effect of Time Window for Umbilical Cord Clamping During Cesareans on Offspring Hemoglobin and Maternal Blood Loss
This is a randomized controlled trial, aiming to evaluate the effects of time window for umbilical cord clamping during cesarean section on the health outcomes of offspring hemoglobin，maternal blood loss，and children's growth and…
- Conditions
- Delayed Cord Clamping, Hemoglobin, Blood Loss
- Trial name
- NCT05492214
- Testing
- Delayed cord clamping (30s), Delayed cord clamping (60s), Delayed cord clamping (90s)
- Where
- 2 sites in China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Peking University
Preterm, General Movements
Fidgety Movements of Preterm Neonates Included in COSGOD III
The evidence on the effects of clinical care with cerebral NIRS (Near-infrared spectroscopy) monitoring on short term neurological outcome, displayed by fidgety movements between six to 20 weeks post term, are still uncertain.
- Conditions
- Preterm, General Movements, Fidgety Movements, Near Infrared Spectroscopy
- Trial name
- Figdety_Ms (NCT06105333)
- Testing
- standard care plus cerebral oxygen saturation monitoring with a dedicated treatment guideline
- Where
- 2 sites in Austria
- Volunteers
- 183 people
- Sponsor
- Medical University of Graz
Neonates Premature
Longterm Outcome of Children With Neonatal Intra-Ventricular or Intra-Cranial Hemorrhage
Intraventricular hemorrhage (IVH) is the most commonly recognized cerebral lesion on ultrasound in extremely preterm infants. Papile classification is commonly used to grade the severity of IVH.
- Trial name
- NEONATAL ICH (NCT03019692)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Laniado Hospital
Morbidity;Newborn, Morality
Improving Outcome of Very Preterm Infants Using Collaborative Quality Improvement
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants in six neonatal centers in Shanghai
- Trial name
- NCT04531839
- Testing
- Evidence-based collaborative quality improvement
- Where
- 6 sites in China
- Sponsor
- Children's Hospital of Fudan University