Clinical trials: Neonatal Surgery
Glaucoma Open-Angle, Glaucoma Eye
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in…
- Conditions
- Glaucoma Open-Angle, Glaucoma Eye, Glaucoma; Drugs, Glaucoma, Angle-Closure
- Trial name
- NCT04381611
- Where
- Switzerland
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Dr. Kaweh Mansouri
Circumcision, Male
Gomco Versus Mogen: Which is Best? A Randomized Controlled Trial
The purpose of this study is to compare two commonly used circumcision clamps (Gomco and Mogen) to see which results in less neonatal pain.
- Trial name
- GMRT (NCT01726036)
- Testing
- Gomco Circumcision Clamp, Mogen Circumcision Clamp
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Obesity, Hypoglycemia Post Gastric Bypass Surgery
GLP1R-imaging in Post-RYGB Hypoglycemia
In order to evaluate the difference in beta cell mass in patients with and without hyperinsulinemic hypoglycemia after Roux en Y gastric bypass (RYGB) investigators aim to compare quantitative PET imaging of the pancreas between…
- Conditions
- Obesity, Hypoglycemia Post Gastric Bypass Surgery, Hyperinsulinemic Hypoglycemia
- Trial name
- NCT05597475
- Testing
- GLP-1R PET
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Pain Insensitivity, Congenital
Comparison of Levobupivacaine, Ropivacaine and Bupivacaine in Epidural Anaesthesia
This study compares the clinical efficacy of newer local anaesthetic drugs Levobupivacaine and Ropivacaine with Bupivacaine in lumbar epidural anaesthesia for hip surgeries.
- Trial name
- NCT02513433
- Testing
- Bupivacaine, Levobupivacaine, Ropivacaine
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Cardiac Valve Disease
Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Cardiac Surgery
The primary endpoint of this study is the completion time of hemostasis treatment when administered Fresh frozen plasma (FFP) and frozen powder coagulation factor concentrate (PCC) in goal-directed bleeding management for cardiac…
- Trial name
- NCT06144125
- Testing
- fresh frozen plasma, prothrombin complex concentrate
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Laryngomalacia, Sleep Apnea, Obstructive
Laryngomalacia, Examinations and Quality of Life in Children Before and After Treatment With Follow-up After 1 Year
Laryngomalacia is the most frequent cause of stridor in children under 1 year. The airway obstruction generates turbulent airway flow and creates the characteristic high-frequency stridor sound.
- Conditions
- Laryngomalacia, Sleep Apnea, Obstructive, Sleep Apnea, Ear, Nose and Throat Disorder
- Trial name
- NCT06464757
- Where
- 2 sites in Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Postoperative Neurogenic Lower Urinary Tract Dysfunction Secondary to Tethered Cord Syndrome
Effectiveness of Electrical Pudendal Nerve Stimulation for Neurogenic Lower Urinary Tract Dysfunction in Pediatric Tethered Cord Syndrome Post-Surgery
The goal of this prospective observational study is to evaluate whether the addition of electrical pudendal nerve stimulation (EPNS) to standard conservative treatment can improve bladder function in pediatric patients with…
- Trial name
- NCT07062133
- Testing
- Electrical pudendal nerve stimulation, Conventional conservative treatment
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Hemophilia A and B, Periodontitis
Effect of Non-Surgical Periodontal Treatment on Oral Health in Hemophilia Patients
This study aimed to evaluate the effect of non-surgical periodontal treatment (NSPT) on oral health-related quality of life in patients with hemophilia using the Oral Health Impact Profile-14 (OHIP-14) questionnaire.
- Conditions
- Hemophilia A and B, Periodontitis, Hemophilia
- Trial name
- NCT07691437
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Cesarean Section, Pregnancy Related
Brain Oxygenation in Newborns Due to Neuroaksial Methods
Epidural and spinal anesthesia techniques are frequently used all over the world in elective cesarean section operations. To evaluate the effects of epidural and spinal anesthesia techniques applied in cesarean section surgery on…
- Conditions
- Cesarean Section, Pregnancy Related, Cerebral Hypoxia, Anesthesia, Regional
- Trial name
- oxygenation (NCT06316596)
- Testing
- Spinal Anesthesia, Epidural Anesthesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Ankyloglossia, Oral Mucoceles
The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day Surgeries
The aim of this double-blinded, randomized, controlled trial was to test whether pre-emptive analgesia with ibuprofen suppository is effective for children undergoing pediatric stomatology day surgeries in the postoperative…
- Conditions
- Ankyloglossia, Oral Mucoceles, Supernumerary Teeth
- Trial name
- NCT05878262
- Testing
- ibuprofen suppository
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Hypospadias, Surgery Non Hypospadias
Glans Size in Hypospadias Compared to Normal
The investigator will collect data on penile and glans size by age, weight and ethnicity in both patients undergoing routine urological surgery and hypospadias surgery.
- Trial name
- NCT03593720
- Testing
- Measurement in Office, Measurement in OR
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Developmental Dysplasia of the Hip
Arthroscopically Assisted Versus Open Surgical Reduction of the Hip in Patients With Irreducible DDH Before the Walking Age
To determine the role of arthroscopy in treatment of the DDH.
- Trial name
- NCT06408987
- Testing
- arthroscopically assisted, open surgical reduction
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Assiut University
Skin Barrier to Water Loss, Skin Health
Apple Peptide Complex for Post-Surgical and Aesthetic Skin Recovery
This clinical study evaluates a topical botanical formulation for supporting skin recovery following invasive and non-invasive aesthetic procedures.
- Conditions
- Skin Barrier to Water Loss, Skin Health, Skin Discoloration, Skin Irritation
- Trial name
- APC-SKIN (NCT07807085)
- Testing
- Apple Peptide Complex Post-Aesthetic Care Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Grow Out Oils Clinical Aromatherapy Company
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Transposition of Great Vessels
Comprehensive Long-term Follow up of Adults With Arterial Switch Operation
Background: Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively…
- Trial name
- EPOCH-ASO (NCT04335448)
- Testing
- No intervention is planed
- Where
- 11 sites in Austria, France and 3 more
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Dysphagia of Newborn
Evaluating Dysphagia in Neonates With CHD
The overall goal of this study is to describe the oral motor skills of neonates born with congenital heart defects, both before and after cardiac surgery, and to evaluate current measures of feeding motor skills and feeding…
- Trial name
- NCT03045757
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Meningomyelocele
Stress-associated Epigenetic Alterations in Newborns After Fetal Surgery
Open spina bifida or myelomeningocele (MMC) is a devastating congenital defect of the central nervous system for which there is no cure. The etiology of MMC remains poorly understood.
- Trial name
- NCT04027374
- Testing
- Fetal surgery for MMC repair
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Vaginal Delivery, Surgical Site Infection
Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with…
- Trial name
- NCT05122169
- Testing
- Povidone-Iodine, Chlorhexidine
- Volunteers
- 4,140 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dentofacial Deformities
Stability of Two Designs of Patient Specific Osteosynthesis For Fixation of LeFort 1 Osteotomy in Orthognathic Surgery
A comparison of the stability of two different designs of patient specific fixation devices for the performance of splintless computer guided le fort 1 osteotomy in orthognathic surgery workflow for the correction of a variety of…
- Trial name
- NCT05522348
- Testing
- Stability of a two piece PSI deign in splintless maxillary orthognathic surgery, Stability of a one piece PSI deign in splintless maxillary orthognathic surgery
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cavernous Malformation, Cerebral, Cavernous Angioma
Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy
Cerebral cavernous malformation (CCM)-related epilepsy (CRE) impairs the quality of life in patients with CCM. Patients could not always achieve seizure freedom after surgical resection of the lesion, suggesting an inadequate…
- Conditions
- Cavernous Malformation, Cerebral, Cavernous Angioma, Cavernous Hemangioma, Cavernous Hemangioma of Brain
- Trial name
- CRESS (NCT04076449)
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- yuanli Zhao