Clinical trials: Neoplasm
T-Cell and NK-Cell Neoplasm
A Global Study of the PETAL Consortium
The goal of this observational study is to correlate molecular alterations with outcomes including overall survival (OS), progression-free survival (PFS), response rates for patients with a new diagnosis, primary refractory or…
- Trial name
- PETAL (NCT06067347)
- Where
- 14 sites in United States, Australia and 2 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Nurse-led Supportive Care
Effect of Nurse-led Supportive Care on Caregiver Burden and Well-being
Breast cancer is the most common type of cancer in women with a high mortality rate in the world. Women may experience many different physiological and psychological symptoms (such as pain, nausea-vomiting, fatigue, stress…
- Trial name
- NCT05470543
- Testing
- Nurse-led supportive care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Neoplastic Cells, Circulating
The Detection of Circulating Tumor Cells (CTCs) in Patients With Renal Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Circulating tumor cells (CTCs) have the potential to provide a surrogate for'real-time biopsy' of tumor biological activity. Enumeration and molecular characterization of CTCs in renal cancer could play an important role in…
- Trial name
- NCT02450448
- Testing
- Flow cytometry (FCM), RT-PCR
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Cervical Cancer
Faster Elimination of HPV Infection and Cervical Cancer Using Concomitant HPV Vaccination and HPV Screening: A Demonstration Project in Rwanda
Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women, with an estimated 604,000 new cases and 342,000 deaths worldwide in 2020.
- Trial name
- NCT06536855
- Testing
- Gardasil 9
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Rwanda Biomedical Centre
Liver Cancer
Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention
To develop and test liver cancer prevention educational material.
- Trial name
- NCT07010315
- Testing
- Cognitive Testing, Usability Testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Nursing, Gynecological Cancers
Effects of a Self-Regulation Based E-MOTE Program Delivered Via an AI-Assisted Robot and Supported by Mobile Platforms for Newly Diagnosed Gynecologic Cancer Patients
To evaluate the effectiveness of the E-MOTE Emotional Care Program, delivered through the Kebbi robot and the LINE Official Account, for patients newly diagnosed with gynecologic cancer undergoing surgery.
- Conditions
- Nursing, Gynecological Cancers, Psycho-Oncology
- Trial name
- NCT07745478
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Leukemia, Lymphoma
Pharmacokinetic Evaluation of Rasburicase in Patients With Leukemia and/or Lymphoma at High Risk of TLS
Primary 1. To determine the pharmacokinetic (PK) parameters of rasburicase in adult patients with leukemia and/or lymphoma at high risk or potential risk of tumor lysis syndrome (TLS) Secondary 1.
- Conditions
- Leukemia, Lymphoma, Tumor Lysis Syndrome
- Trial name
- NCT00360438
- Testing
- Rasburicase
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Nutrition Aspect of Cancer
Testing the Effectiveness of Coping With Cancer in the Kitchen
The study was a two-arm, randomized controlled trial in which cancer survivors were evenly assigned to either receive the 8-week CCK in-person nutrition intervention immediately or to become the control group that received a…
- Trial name
- CCK (NCT04528615)
- Testing
- CCK In-Person Sessions, CCK Printed Materials
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- American Institute for Cancer Research
Uterine Cervical Neoplasms
Imaging the Uterine Cervix - UltraSightHD™
The purpose of this study is to investigate the performance ability of the UltraSightHD™. The instrument will be assessed on characteristics such as focus quality, ability to image the entire cervix, and illumination.
- Trial name
- NCT01090635
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- STI-Medical Systems
Seborrheic Keratosis (SK), Oxidative Stress
Relationship Between Serum Xanthine Oxidase Levels and Seborrheic Keratosis
This observational study aims to examine the relationship between serum xanthine oxidase (XO) levels and seborrheic keratosis (SK), a common benign skin tumor, especially in middle-aged and older adults.
- Conditions
- Seborrheic Keratosis (SK), Oxidative Stress, Skin Aging
- Trial name
- SK-XO (NCT07095348)
- Testing
- Serum Xanthine Oxidase Level Assessment
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sri Nauli Dewi Lubis
Carcinoma, Basal Cell
Debulking Effect of Curretage on Basal Cell Carcinomas - a Histological Assessment.
The aim of this study was to compare histologically observed tumour infitration of basal cell carcinoma (bcc) lesions before and after curretage.A significant reduction of tumour depth would enable further bcc's included for…
- Trial name
- NCT00237107
- Testing
- Curretage
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Neoadjuvant Chemoradiotherapy, Rectal Tumor
Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery
Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal…
- Conditions
- Neoadjuvant Chemoradiotherapy, Rectal Tumor, Surgery, Surgery--Complications
- Trial name
- NCT04013347
- Testing
- Rectal Resection
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Ovarian Neoplasm, Cancer Genetics
Family Communication of Hereditary Breast and Ovarian Cancer Risk Among African Americans
Background: Certain genetic mutations are linked to higher rates of cancer. It is important for people with these mutations to tell their families about it.
- Conditions
- Ovarian Neoplasm, Cancer Genetics, Breast Cancer
- Trial name
- NCT01374685
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Renal Cell Carcinoma, Hepatocellular Carcinoma
A Social Support Intervention to Improve Treatment Among Hispanic Kidney and Liver Cancer Patients in Arizona
This project will develop and pilot test social support intervention for an underserved population, Hispanics in Arizona, who have high rates of kidney and liver cancer to improve health equity.
- Trial name
- NCT05418387
- Testing
- Social Support Network Intervention, Control (Patient Navigation Service)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer
A Survivorship Care Plan for Gynaecological Cancer Patients
After treatment women surviving gynaecological cancer may experience lateeffects and longterm challenges specific to their disease and treatment resulting in functional deficits and a reduction in societal integration (Yabroff et…
- Conditions
- Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer, Endometrial Cancer, Esophageal Cancer
- Trial name
- NCT01582906
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Health Status Unknown, Lung Cancer
Liverpool Lung Project: Risk Factors and Genetic Markers in Healthy Participants and Patients With Lung Cancer
RATIONALE: Environmental exposure and genetic predisposition may affect the risk of developing cancer later in life. Learning about genetic markers and the long-term effects of environmental exposure may help the study of lung…
- Trial name
- NCT00503958
- Testing
- DNA methylation analysis, DNA stability analysis, gene expression analysis
- Where
- 5 sites in United Kingdom
- Volunteers
- 8,300 people, healthy volunteers welcome
- Sponsor
- University of Liverpool Cancer Research Centre
Pulmonary Nodules, Multiple
Detection and Volumetry of Pulmonary Nodules on Ultra-low Dose Chest CT Scan With Deeplearning Image Reconstruction Algorithm (DLIR)
evaluate the diagnostic performance of ultra-low dose CT using deep learning-based reconstruction in the detection of pulmonary nodules.
- Trial name
- DLIRTHORAX (NCT04482114)
- Testing
- ULD CT
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Kidney Neoplasm, Renal Cancer
Stereotactic Body Radiotherapy (SBRT) for Medically Inoperable Localised Renal Tumors (SABINA Trial)
Study evaluating the activity and efficacy of Stereotactic Body Radiotherapy for the treatment of medically inoperable localized renal cancer
- Conditions
- Kidney Neoplasm, Renal Cancer, Inoperable Disease, SBRT
- Trial name
- SABINA (NCT05817604)
- Testing
- SBRT
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Genital Diseases, Female, Ovarian Neoplasms
Pharmacokinetic Study on the Administration of Nadroparin Dosing Serum HGF in Gynecological Patients
The purpose of this study is to determine whether HGF serum concentration might be raised in vivo by administering nadroparin given with prophylactic purpose to gynecological patients.
- Conditions
- Genital Diseases, Female, Ovarian Neoplasms, Urogenital Neoplasms
- Trial name
- NCT01523652
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
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