Clinical trials: Neoplasm
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Early Detection of Cancer
A Questionnaire for Endoscopic Prediction Improvement of Gastrointestinal Cancer
Despite improvements in a range of chemo, radio and surgical therapies, the overall survival at 5 years from gastrointestinal cancer remains poor.
- Trial name
- NCT04071431
- Testing
- Result masking
- Where
- China
- Volunteers
- 34,906 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Prostate Cancer
Study of Docetaxel +153 Sm-EDTMP in Patients With Hormone-Refractory Prostate Cancer
The primary objective of the study is to determine a recommended phase II dose (RP2D). The secondary objective of the study are: 1.
- Trial name
- Tax-Sam (NCT00559429)
- Testing
- Docetaxel
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cancer
Hemodynamic Monitoring in Hepatopancreaticobiliary (HPB) Surgery
This is a pilot study with the primary objective to validate the use of advanced minimally invasive hemodynamic monitoring with the PreSep™ Central Venous Oximetry Catheter, the Vigileo™ monitor, and FloTrac™ sensor for…
- Trial name
- NCT03612687
- Testing
- Minimally invasive hemodynamic monitoring
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy
To Evaluate the Effects of Omega 3 Fatty Acids in the Context of Cancer Prevention
Previous studies have demonstrated, in an in vitro micro-tumour model (the spheroid) and in a mouse model, that long-chain omega-3 fatty acids, in particular docosahexaenoic acid (DHA), can inhibit tumour development.
- Trial name
- NCT05427604
- Testing
- Olive oil, DHA oil
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Metabolic Syndrome, Obesity Associated Disorder
Dedicated Breast CT for Quantitative Breast Density Measurements in Mexican-origin Women in Southern Arizona
The overall objective of this clinical study is to determine the feasibility of breast CT for breast density assessment and association of CT-derived density measures with metabolic syndrome in overweight/obese Mexican-origin…
- Trial name
- NCT04799665
- Testing
- Breast CT
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Hearing Loss, Cancer
Study to Evaluate the Safety and Pharmacokinetics of SPI-1005
A study to determine the safety, tolerability, and pharmacokinetics of SPI-1005 capsules in healthy adults.
- Trial name
- NCT01452607
- Testing
- SPI-1005
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sound Pharmaceuticals, Incorporated
Breast Cancer Female
High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women
The purpose of this second pilot study is to extend the feasibility demonstrated in NCT02963740 that the intervention achieves high levels of moderate to vigorous physical activity (MVI PA) and modulates risk biomarkers for…
- Trial name
- NCT03270111
- Testing
- Supervised Exercise, Home-based Exercise, Reduced Energy Diet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Anovulation, Hyperandrogenism
Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome
Background: Infertility affects up to 15% of married couples. About half are attributable to female factors, among which anovulation is the leading cause.
- Conditions
- Anovulation, Hyperandrogenism, Polycystic Ovary Syndrome, Single Nucleotide Polymorphism
- Trial name
- NCT00665171
- Where
- Israel
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Maaynei Hayesha Medical Center
Stage IV Gastric Cancer With Metastasis, Hyperthermic Intraperitoneal Chemotherapy
Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer With Peritoneal Metastatis
The incidence rate of gastric cancer is high in Southeast Asia, so is the mortality rate.Due to the lack of specific performance, about 5%-20% of patients have found peritoneal metastases at the time of first diagnosis.At…
- Conditions
- Stage IV Gastric Cancer With Metastasis, Hyperthermic Intraperitoneal Chemotherapy, Exploratory Behavior
- Trial name
- NCT03604614
- Testing
- Hyperthermic Intraperitoneal Chemotherapy, Without Hyperthermic Intraperitoneal Chemotherapy
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia
Donor-Derived Humoral Immunity, Hematopoietic Stem Cell Transplantation, TAR
This research study is for subjects that are receiving a bone marrow transplant. As part of the transplant subjects will receive stem cells from a donor who has agreed to donate stem cells for them.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome
- Trial name
- TAR (NCT01611298)
- Testing
- Tetanus
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Robert Krance
Cancer
Diagnosis of Cancer Using Breath Samples
The purpose of this study is to collect breath samples from healthy and cancer sick patients. The breath, collected to special bags, will be transferred to laboratories in the Technion and analyzed using an electronic nose system…
- Trial name
- NCT01234987
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
Obesity Prevention, Cancer Prevention
Effectiveness of the Croq'Santé Nutrition Education Program in Improving Food Literacy in Schoolchildren
Background: Nutritional factors including diet, physical activity, weight status and alcohol consumption are among the most important preventable risk factors for cancer.
- Trial name
- NCT06796244
- Testing
- Croq'Santé nutrition education program
- Where
- France
- Volunteers
- 1,205 people, healthy volunteers welcome
- Sponsor
- Marie HERR
Healthy Participants
A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants
This study will be conducted in order to determine the effect of repeated oral doses of camizestrant on the pharmacokinetics (PK) of midazolam and to determine the effect of repeated oral titrated doses of carbamazepine on the PK…
- Trial name
- NCT06547164
- Testing
- Midazolam, Camizestrant, Carbamazepine
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Actinic Keratosis, Natural Daylight Photodynamic Therapy
Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)
This study compares two photosensitizing creams' BF-200 ALA's (aminolevulinic acid, Ameluz®) and MAL's (methyl 5-aminolevulinate, Metvix®) efficacy on actinic keratoses in natural daylight photodynamic therapy (NDL-PDT).
- Trial name
- NCT02464709
- Testing
- Aminolevulinic Acid, Methyl 5-aminolevulinate
- Where
- 3 sites in Finland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
CRC, Advanced Neoplasia
Prospective Clinical Validation of a Novel Multitarget FIT in CRC Screening
The primary goal of the population-based colorectal (CRC) screening is early detection and interception of CRC and its precursors to decrease CRC-related morbidity and mortality.
- Trial name
- mtFIT (NCT05314309)
- Testing
- Comparison of two tests (FIT and mtFIT) in the same bowel movement
- Where
- Netherlands
- Volunteers
- 14,712 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Lichen Sclerosus
Genital Lichen Sclerosus - Epidemiology, Comorbidities and the Role of Vulvar and Penile Microbiome
In genital LSc, three pathological processes are implicated in disease development: inflammation, sclerosis/fibrosis and neoplasia. The role of genital microbiome is still to be investigated and explained.
- Trial name
- NCT05671263
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Region Jönköping County
Breast Cancer
Prospective Chart-Review: Impact of Combination - Digital Breast Tomosynthesis + Digital Mammography
Digital Breast Tomosynthesis (DBT) is a technology that has been developed to improve lesion detection in dense breasted women. Even though DBT has been regarded as a study for dense breasted women, it may also improve lesion…
- Trial name
- NCT01593384
- Volunteers
- healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Quality of Life, Pediatric Cancer
Intervention Development and Evaluation to Reduce Disparities in Quality of Life for Latino Families Impacted by Cancer
The purpose of this study is to determine if a culturally relevant caregiver intervention is effective in decreasing stress and improving quality of life in Spanish speaking Latino caregivers of children diagnosed with cancer…
- Conditions
- Quality of Life, Pediatric Cancer, Caregiver Burden
- Trial name
- NCT06622252
- Testing
- 13-week session program
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Testicular Cancer
The Effect of the Brochure on Testicular Self-Exam
This study aims to examine the effect of the educational brochure given to university students on testicular cancer and its early diagnosis on their health beliefs and self-examination; In non-randomized groups, pretest-posttest…
- Trial name
- NCT05073198
- Testing
- Education brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Selcuk University
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