Clinical trials: Nephrolithotomy, Percutaneous
Percutaneous Nephrolithotomy, Infection
Conventional Antibiotic Prophylaxis Versus Add-On 5 Days Levofloxacin Before Percutaneous Nephrolithotomy
To evaluate whether 5 days of levofloxacin before percutaneous nephrolithotomy (PCNL) in reducing upper urinary tract infection and urosepsis after PCNL.
- Conditions
- Percutaneous Nephrolithotomy, Infection, Sepsis, Antibiotics
- Trial name
- NCT03178292
- Testing
- Levofloxacin
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Kidney Stone
Robotic-assisted Percutaneous Access
This is a first-in-man (FIM) study to show feasibility and safety profile of the newly developed robotic device for percutaneous access in PCNL surgery.
- Trial name
- NCT04435132
- Testing
- PCL under fluoroscopy with the aid of the robotic device
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- NDR Medical Technology Pte Ltd
Percutaneous Nephrolithotomy (PCNL), Perioperative Analgesia
Anterior QLB for PCNL
Aim: In this study, we primarily aimed to determine the effect of anterior Quadratus Lumborum Block (QLB) on intraoperative and postoperative opioid consumption in patients undergoing percutaneous nephrolithotomy (PCNL) surgery…
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Perioperative Analgesia, Quadratus Lumborum Block, Opioid Consumption
- Trial name
- NCT07487415
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK ( anterior QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Zonguldak Bulent Ecevit University
Kidney Calculi, Postoperative Pain
Is it Really Necessary to Insert a Nephrostomy Tube or Double J Stent in Percutaneous Nephrolithotomy?
In this study, investigators aimed to compare the postoperative pain status and comfort situations depending on instruments used in the percutaneous nephrolithotomy operation
- Trial name
- NCT06062849
- Testing
- nephrostomy tube, double J stent, totally tubless
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Nephrolithiasis
Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment
Extensive literature exists on the use of alpha-blocker medications for the removal of kidney stones. Alpha blockers relax certain muscles and help small blood vessels remain open.
- Trial name
- NCT03229889
- Testing
- Cialis 5Mg Tablet, Flomax 0.4Mg Capsule, Cialis + Flomax
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of California, Irvine
Renal Stones, Postoperative Pain
Comparison of Tubeless Versus Standard Percutaneous Nephrolithotomy (PCNL) for Renal Stones
Percutaneous nephrolithotomy (PCNL) is the surgery usually done to break down kidney stones that are larger than 1.5 cm. Placing a nephrostomy tube after the surgery to drain urine is a common aspect of traditional PCNL.
- Trial name
- TPCNL (NCT07522619)
- Testing
- Standard Percutaneous Nephrolithotomy (Standard PCNL), Tubeless Percutaneous Nephrolithotomy (Tubeless PCNL)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Indus Hospital and Health Network
Erector Spinae Plane Block, Nephrolithotomy, Hyaluronidase
Efficacy of Hyaluronidase Added to Bupivacaine in Ultrasound-guided Erector Spinae Plane Block in Percutaneous Nephrolithotomy.
Evaluation of the postoperative pain via numeric rating scale (NRS) through erector spinae plane block (ESPB) by adding hyaluronidase as an adjuvant to bupivacaine on the postoperative analgesia in erector spinae plane block.
- Trial name
- NCT07102771
- Testing
- Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Safety, Efficacy
Safety and Efficacy of Papillary Versus NonPapillary Access During Percutaneous Nephrolithotomy
This study aims to evaluate and compare the safety, efficacy, and clinical outcomes of papillary and non-papillary renal access during percutaneous nephrolithotomy (PCNL), and to determine whether non-papillary puncture can be…
- Conditions
- Safety, Efficacy, Papillary, NonPapillary
- Trial name
- NCT07855354
- Testing
- Papillary access puncture, Non-papillary access puncture
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Percutaneous Nephrolithotomy
Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is the surgical standard for treating large or complex renal stones. The stones are removed by passing a small telescope through the side of the patient directly into the kidney, so the stone…
- Trial name
- NCT04891484
- Testing
- Ondansetron group, Saline group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Surgery, Nurse's Role
Effects of Aromatic Solution Applied After Surgery
Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required.
- Conditions
- Surgery, Nurse's Role, Throat, Sore, Thirst
- Trial name
- NCT05522023
- Testing
- group treated with aromatic solution, group treated with drinking water
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Renal Calculi, Postoperative Pain
Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy
Percutaneous nephrostolithotomy (PCNL) is a common endoscopic procedure performed for upper urinary tract calculus disease. Despite being minimally invasive, it is associated with significant postoperative pain, often…
- Trial name
- NCT03043027
- Testing
- liposomal bupivicaine, Bupivacaine, Saline Solution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Kidney Stones
FANS-Assisted Mini-PCNL for Complex Renal Stones
This prospective pilot study aims to evaluate the feasibility, safety, and preliminary clinical outcomes of a novel mini-percutaneous nephrolithotomy (mini-PCNL) technique integrating a flexible mini-nephroscope with a flexible…
- Trial name
- FANS-MiniPerc (NCT07332286)
- Testing
- FANS-assisted mini-percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Stone, Kidney, Urolithiasis
Staged Bilateral Percutaneous Nephrolithotomy
To determine the optimal time between the first and second operations in patients with bilateral kidney stones and scheduled percutaneous nephrolithotomy for the contralateral kidney.
- Trial name
- NCT05340075
- Testing
- Patients who underwent percutaneous nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Training and Research Hospital
Analgesia, Surgery
U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is considered to be the first choice and a more conservative procedure than open stone surgery.
- Conditions
- Analgesia, Surgery, Renal Stone
- Trial name
- NCT04800302
- Testing
- Continous Quadratum Lumborum Block III, Single dose Quadratum Lumborum Block III, Intra-venous Morphine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nazmy Edward Seif
Kidney Stones, Complex Renal Calculi
Modified Mini-PCNL Versus Standard PCNL for Complex Kidney Stones
Kidney stones that are large or complex are often treated with percutaneous nephrolithotomy, also called PCNL. Standard PCNL uses a larger access tract and is effective for removing complex kidney stones, but it may be associated…
- Trial name
- MIMIC-PCNL (NCT07697677)
- Testing
- 20 Fr Modified Mini Percutaneous Nephrolithotomy, 24 Fr Standard Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,380 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Nephrolithiasis
Early vs Delayed Extracorporeal Shock Wave Lithotripsy for Residual Stones After Percutaneous Nephrolithotomy
Residual renal stone fragments remain a common clinical issue following percutaneous nephrolithotomy (PCNL), with reported incidence ranging from 10% to 30%.
- Trial name
- NCT07523074
- Testing
- Extracorporeal shock wave lithotripsy (ESWL)
- Where
- Egypt
- Volunteers
- 476 people
- Sponsor
- Beni-Suef University
Nephrolithiasis
Trial Comparing the Effect of a Paravertebral Block on Pain Post Percutaneous Nephrolithotomy
This is a randomized control trial (meaning the selection is random as when flipping a coin) to assess the benefit of paravertebral blockade (PVB) in Percutaneous nephrolithotomy/nephrolithotripsy (PCNL) surgery.
- Trial name
- NCT01371422
- Testing
- Paravertebral Block (PVB), Saline
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Nephrolithotomy, Percutaneous, Kidney Stone
The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL
To analyze and compare the puncture success rate, puncture fluoroscopy time and intraoperative puncture complications of two different puncture techniques; fluoroscopic bi-planar (0-30º) versus newly reported bi-planar (0-90º)…
- Conditions
- Nephrolithotomy, Percutaneous, Kidney Stone, PCNL
- Trial name
- NCT04557722
- Testing
- 0-30° Biplanar Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy, New 0-90° Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Nephrolithiasis of Both Kidneys
Bilateral Percutaneous Nephrolithomy
The purpose of this study is to determine the effective regimen for definitive surgical therapy of bilateral kidney stones. It is unknown whether patients who undergo simultaneous bilateral percutaneous nephrolithotomy (PCNL)…
- Trial name
- NCT03924362
- Testing
- PCNL
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Kidney Stones
Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
- Trial name
- NCT01922414
- Testing
- Laser, Ultrasonic
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University