Clinical trials: Nephrolithotomy
Renal Calculi
The Influence of SMP on Renal Pelvic Pressure In Vivo
Percutaneous nephrolithotomy (PCNL) is a well-established treatment modality for renal stones. It offers a high stone free rates and less invasive than open surgery.
- Trial name
- NCT02760134
- Testing
- Super-Mini Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Quadratus Lumborum Block, Percutaneous Nephrolithotomy
Quadratus Lumborum Block as an Anesthetic Method for Percutaneous Nephrolithotomy
The study aims to investigate the efficacy and safety of QLB, as an anaesthetic method, for patients undergoing PCNL. Adult patients who agree to participate in the study will be included.
- Conditions
- Quadratus Lumborum Block, Percutaneous Nephrolithotomy, Local Anesthesia
- Trial name
- NCT04852874
- Testing
- Ultrasound-guided Quadratus Lumborum Block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Erector Spinae Plane Block, Nephrolithotomy, Hyaluronidase
Efficacy of Hyaluronidase Added to Bupivacaine in Ultrasound-guided Erector Spinae Plane Block in Percutaneous Nephrolithotomy.
Evaluation of the postoperative pain via numeric rating scale (NRS) through erector spinae plane block (ESPB) by adding hyaluronidase as an adjuvant to bupivacaine on the postoperative analgesia in erector spinae plane block.
- Trial name
- NCT07102771
- Testing
- Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Kidney Stones
Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy
The investigators main hypothesis is that the stone free rate will be much higher (95%) in patients treated with PCNL than patients treated with ESWL where stone free rate is (60%) to determine which treatment is safe and prevent…
- Trial name
- NCT00873054
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Kidney Stones
Occlusion Balloon vs. 5FR Ureteral Catheter
Occlusion Balloon catheter provides the ability to occlude the exit of the kidney pelvis during percutaneous nephrolithotomy (PCNL) and potentially prevents the migration of stone fragments into the ureter.
- Trial name
- NCT06798753
- Testing
- Occlusion Balloon Catheter, 5FR Ureteral Catheter
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Kidney Stone
RIRS With Tip Flexible Pressure-controlling Ureteral Access Sheath Versus Mini PCNLfor Kidney Stones
The goal of this observational study is to compare the safety and efficacy between RIRS with tip flexible pressure-controlling ureteral access sheath and mini percutaneous nephrolithotripsy（PCNL） for the treatment of 2-3-cm…
- Trial name
- NCT06209931
- Testing
- RIRS
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Pleural Effusion
Tubeless Versus Standard Upper Pole Percutaneous Nephrolithotomy
Comparison of complications between standard upper pole percutaneous nephrolithotomy (PCNL) with nephrostomy placement and double J stent and PCNL with double J placement only without nephrostomy.
- Trial name
- NCT02036398
- Testing
- Double J stent without nephrostomy, nephrostomy tube and double J stent
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Rabin Medical Center
Kidney Stones
Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL
The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be…
- Trial name
- NCT00784472
- Testing
- oxycodone, morphine
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Katja venborg Pedersen
Renal Stone, Percutaneous Nephrolithotomy
Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones
The optimal management of medium-sized renal stones remains quite challenging and continues to be contested. In the present study, the investigators will compare mini-PNL, RIRS and SWL in the treatment of non- lower pole, medium…
- Conditions
- Renal Stone, Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Extracorporeal Shockwave Lithotripsy
- Trial name
- NCT04856722
- Testing
- mini-PNL, RIRS, SWL
- Where
- Egypt
- Volunteers
- 253 people
- Sponsor
- Al-Azhar University
Kidney Stones
Ho:YAG Laser Versus Thulium Laser for the Management of 2-4cm Kidney Stones During SMP
With the rapid development of medical equipment and the increasing experience, minimally invasive percutaneous nephrolithotomy (mini-PCNL) has been a well established modality for the management of upper urinary tract stones.
- Trial name
- NCT05190536
- Testing
- Ho:YAG lasers, TFL
- Where
- China
- Volunteers
- 682 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Stone
Comparison of Surgical Outcomes Between MPCNL and RIRS
The objective of this research is to investigate the surgical outcomes of minimally invasive percutaneous nephrolithotomy(MPCNL) and retrograde intrarenal surgery (RIRS)for patients with renal stone larger than 1cm.
- Trial name
- NCT02067221
- Testing
- RIRS, MPCNL
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Renal Stone, Extracorporeal Shockwave Lithotripsy
Mini- Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy for High Density Renal Stones
Several studies were conducted to compare extracorporeal shockwave lithotripsy (SWL) and percutaneous nephrolithotomy (PNL) as treatment options for medium size lower caliceal high dense stones.
- Conditions
- Renal Stone, Extracorporeal Shockwave Lithotripsy, Percutaneous Nephrolithotomy
- Trial name
- NCT04346134
- Testing
- mini-PNL, SWL
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Al-Azhar University
Urolithiasis
A Prospective Comparison of Fluoroscopic, Sonographic or Combined Approach for Renal Access in Percutaneous Nephrolithotomy
Purpose: The aim of this present study is to compare the result of fluoroscopy, ultrasonography (US) and US combined with fluoroscopy in the guidance of minimally invasive percutaneous nephrolithotomy (MPCNL).
- Trial name
- NCT02266381
- Testing
- US-guided renal access, Fluoroscopy-guided renal access, US combined with fluoroscopy-guided renal access
- Where
- China
- Volunteers
- 450 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Percutaneous Nephrolithotomy (PCNL), Postoperative Pain
The Effect of NSAID Steroid Therapy for PGE2 Level and Analgesia After Percutaneous Nephrolithotomy Surgery
The goal of this clinical trial is to learn if combination of NSAID-steroid can decrease the PGE2 level and postoperative pain after percutaneous nephrolithotomy surgery.
- Trial name
- BUPARDEX (NCT06604598)
- Testing
- IBU-PCT-DEX
- Where
- Indonesia
- Volunteers
- 45 people
- Sponsor
- Universitas Jenderal Soedirman
Pain, Postoperative Pain
Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt…
- Trial name
- NCT04835116
- Testing
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg., paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Percutaneous Nephrolithotomy
Flexible Nephroscopy-Assisted Single-Tract Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones
This randomized, parallel-group, non-inferiority trial will compare flexible nephroscopy-assisted single-tract percutaneous nephrolithotomy with conventional multi-tract percutaneous nephrolithotomy in patients with complex…
- Trial name
- NCT07753733
- Testing
- Flexible Nephroscopy-Assisted Single-Tract PCNL, Conventional Multi-Tract PCNL
- Where
- Egypt
- Volunteers
- 470 people
- Sponsor
- Al-Azhar University
Urinary Calculi, Percutaneous Nephrolithotomy
Tubeless Percutaneous Nephrolithotomy Without Reverse Insertion of a Ureteral Catheter
Percutaneous nephrolithotomy(PCNL) is a surgical method for upper urinary calculi. The advent of tubeless PCNL (without indwelling nephrostomy tube) has been proved to be safe and effective in reducing postoperative discomfort…
- Trial name
- NCT05574517
- Testing
- Without reverse insertion of a ureteral catheter
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of University of South China
Nephrolithiasis, Postoperative Inflammation
Inflammatory Response Under Spinal vs General Anesthesia in PCNL: NLR, RDW, LAR.
This observational study compares the effects of spinal versus general anesthesia on the perioperative systemic inflammatory response in adults undergoing PCNL.
- Trial name
- SAGEPCNL (NCT07205224)
- Testing
- Anesthesia Type
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sevim Şenol Karataş
Stone, Kidney, Stone, Urinary
FANS-FURS vs Suction Mini-PCNL for 2-3 cm Renal Stones: A Multicenter Randomized Trial
This multicenter, prospective, randomized clinical trial compares FANS-assisted flexible ureteroscopy (FURS) with suction-assisted mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of renal stones measuring 2-3 cm.
- Trial name
- NILE (NCT07295860)
- Testing
- FANS-Based Flexible Ureteroscopy (FURS), Suction-Assisted Mini-PCNL
- Where
- 9 sites in Egypt
- Volunteers
- 254 people
- Sponsor
- Mansoura University