Clinical trials: Nephrolithotomy
Renal Stone Disease
Intrarenal Pressure Monitoring During Pediatric Percutaneous Nephrolithotomy, and Its Impact on Post Operative Infectious Complications.
Monitoring of intrarenal pressure during pediatric percutaneous nephrolithotomy and its impact on post operative infectious complications.
- Trial name
- NCT07800546
- Testing
- Intrarenal pressure
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Percutaneous Nephrolithotomy
Application of 3DSlicer Technology in Percutaneous Nephrolithotomy Surgery.
Objectives: Percutaneous nephrolithotomy (PCNL) has become a widely used technique for managing renal calculi. However, the rate of residual stones remains high.
- Trial name
- NCT07299643
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ting Huang
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
The goal of this observational study is to investigate the feasibility of ultrasound-guided percutaneus nephrolithotomy in patients with kidney stones.
- Trial name
- PCNL (NCT06922006)
- Testing
- Percutaneus nephrolithotomy (PCNL)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Nephrolithiasis
The Success of Pediatric Percutaneous Nephrolithotomy
Between June 1997-June 2018, 573 pediatric patients underwent PCNL for renal stone disease by senior surgeons. Data was disunited into 2 groups.
- Trial name
- NCT04299204
- Testing
- Percutaneous nephrolitotomy
- Volunteers
- 553 people
- Sponsor
- Osmaniye Government Hospital
Renal Stones, Nephrolithiasis
Efficacy of Tranexamic Acid on Blood Loss During Percutaneous Nephrolithotomy.
Efficacy of tranexamic acid on blood loss during percutaneous nephrolithotomy. a double-blind, placebo-controlled randomized clinical trial.
- Trial name
- NCT04367155
- Testing
- Tranexamic acid injection
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Spinal Anesthesia, Percutaneous Nephrolithotomy
Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation
The aim of this study is to evaluate the efficacy of spinal anesthesia as an alternative to general anesthesia in PCNL operation in supine position.
- Conditions
- Spinal Anesthesia, Percutaneous Nephrolithotomy, General Anesthesia
- Trial name
- NCT07114250
- Testing
- spinal anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Kidney Calculi
Mini-PCNL Versus Standard-PCNL For The Management of 20-40 mm Size Kidney Stones
Percutaneous nephrolithotomy (PCNL) has been considered as the first-line choice for the management of >20mm kidney stones. The traditional nephrostomy tract of PNL was dilated to 24-30F, which is referred to as "Standard-PCNL".
- Trial name
- NCT02635048
- Testing
- Mini Percutaneous Nephrolithotomy, Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,980 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Stones, Kidney, Stones Ureter
Flexible Ureteroscopy Versus Percutaneous Nephrolithotomy As Primary Treatment in Renal Stones 2-3 Cm
Flexible Ureteroscopy versus Percutaneous Nephrolithotomy as Primary Treatment in Renal Stones 2-3 Cm
- Conditions
- Stones, Kidney, Stones Ureter, Urolithiasis
- Trial name
- NCT06892626
- Testing
- RIRS, PNL
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Analgesia, Surgery
U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is considered to be the first choice and a more conservative procedure than open stone surgery.
- Conditions
- Analgesia, Surgery, Renal Stone
- Trial name
- NCT04800302
- Testing
- Continous Quadratum Lumborum Block III, Single dose Quadratum Lumborum Block III, Intra-venous Morphine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nazmy Edward Seif
Nephrolithiasis
Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment
Extensive literature exists on the use of alpha-blocker medications for the removal of kidney stones. Alpha blockers relax certain muscles and help small blood vessels remain open.
- Trial name
- NCT03229889
- Testing
- Cialis 5Mg Tablet, Flomax 0.4Mg Capsule, Cialis + Flomax
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of California, Irvine
MINS, Myocardial Injury After Noncardiac Surgery
Comparison of Myocardial Injury After Noncardiac Surgery (MINS) Incidence in Supine vs. Prone Positioning During Percutaneous Nephrolithotomy (PNL)
This prospective cohort study aims to compare the incidence of Myocardial Injury after Noncardiac Surgery (MINS) in patients undergoing percutaneous nephrolithotomy (PNL) for kidney stones in supine versus prone positioning.
- Conditions
- MINS, Myocardial Injury After Noncardiac Surgery, Myocardial Injury After Noncardiac Surgery (MINS), Renal Calculi
- Trial name
- NCT06944301
- Testing
- blood sampling
- Volunteers
- 400 people
- Sponsor
- Medipol University
Nephrolithiasis, Postoperative Pain
Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure used to remove large or complex kidney stones. Although effective, dilation of the surgical tract and the placement of a nephrostomy tube cause…
- Conditions
- Nephrolithiasis, Postoperative Pain, Quality of Recovery
- Trial name
- NCT07855068
- Testing
- Ketamine and Dexmedetomidine, Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
Renal Calculi
SMP vs RIRS for Symptomatic Lower Pole Renal Calculi of 10-20 mm Size: a Randomized Controlled Trial
Shock wave lithotripsy (SWL) is recommended for kidney stones < 20 mm. However, the stone clearance of lower pole calculi after SWL is limited, thus leading to an extended indication for mini-percutaneous nephrolithotripsy (PCNL)…
- Trial name
- NCT02519634
- Testing
- Super-Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Stone
The Efficacy of Peritubal Analgesic Infiltration in Postoperative Pain Following Percutaneous Nephrolithotomy
The investigators aim to investigate the effect of peritubal local anesthetic infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy.
- Trial name
- NCT04160936
- Testing
- Marcaine Injectable Product
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Saddam Al Demour
Kidney Stone
MIP Versus PCNL for Kidney Stone Disease
The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community.
- Trial name
- NCT04767919
- Testing
- Standard Percutaneous Nephrolithotomy (sPCNL), Minimally Invasive Percutaneous Nephrolithotomy (MIP)
- Where
- 6 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- University of California, San Diego
Renal Stone
Flexible Mini Percutaneous Nephrolithotomy Vs Retrograde Intra-renal Surgery
The use of flexible ureteroscopy and minimally-invasive percutaneous techniques, which utilize smaller tract sizes, has been established as a way to decrease the invasiveness of procedures and improve patient outcomes compared to…
- Trial name
- NCT06249100
- Testing
- flexible mini percutaneous nephrolithotomy, Retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Postoperative Pain, Nephrolithiasis
A Randomized, Double-Blind, Placebo-Controlled Trial of Anrikefon for Postoperative Analgesia After Percutaneous Nephrolithotomy
This study evaluates whether a single dose of anrikefon, given intravenously shortly before the end of kidney stone removal surgery (PCNL), can reduce opioid-related side effects such as nausea, vomiting, itching, oversedation…
- Trial name
- ARK-PCNL (NCT07825142)
- Testing
- Anrikefon
- Volunteers
- 160 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Nephrolithiasis, Urosepsis
Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy.
The aim of the study is to establish an infectious risk stratification system based on pre-and post-operative blood endotoxin profile.
- Trial name
- NCT04669886
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Nephrolithiasis
Efficacy of Ciprofloxacin Therapy in Avoidance of Sepsis in Patient Undergoing Percutanous Nephrolithotomy
Efficacy of ciprofloxacin therapy in avoidance of sepsis in patient undergoing percutanous nephrolithotomy. A randomized controlled trial.
- Trial name
- NCT04374188
- Testing
- Ciprofloxacin, Levofloxacin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Diaa Eldin Taha Ramadan Mohamed