Clinical trials: Nephrolithotomy
Nephrolithiasis, Kidney Stone
Mini-PNCL vs fURS in Management of Nephrolithiasis
The prevalence of nephrolithiasis is increasing over the last two decades, and kidney stones is a recurrent disorder, with lifetime recurrence risks reported to be as high as 50%.
- Trial name
- NCT04389853
- Testing
- Flexible ureteroscopy, Mini-percutaneous nephrolithotomy
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Kidney Stones
FANS-Assisted Mini-PCNL for Complex Renal Stones
This prospective pilot study aims to evaluate the feasibility, safety, and preliminary clinical outcomes of a novel mini-percutaneous nephrolithotomy (mini-PCNL) technique integrating a flexible mini-nephroscope with a flexible…
- Trial name
- FANS-MiniPerc (NCT07332286)
- Testing
- FANS-assisted mini-percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Calculi
Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis
Extracorporeal shock wave lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL) become the therapy of choice for renal stone.
- Trial name
- NCT01329042
- Testing
- Potassium-sodium citrate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ouiheng International Healthcare Co., Ltd
Percutaneous Nephrolithotomy (PCNL)
Intrathecal Fentanyl and Dexmedetomidine Added to Bupivacaine for Subarachnoid Anaesthesia for Percutaneous Nephrolithotomy
Regular bupivacaine dosages are linked to considerable sympathetic block, as well as persistent and severe sensory and motor block, which may not be desired for certain individuals.
- Trial name
- NCT06957301
- Testing
- Intrathecal Fentanyl Group (F), intrathecal dexmedetomidine group(D)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Renal Stones
Postoperative Outcomes of PCNL vs RIRS in Obese Patients With Pelvic 1.5:3 cm Renal Stones
This prospective randomized comparative study was done at Helwan University Hospital. It was conducted on 120 patients with unilateral pelvic renal stones from 1.5 to 3 cm in largest diameter who was admitted through duration to…
- Trial name
- PCNL VS RIRS (NCT06175910)
- Testing
- percutaneous nephrolithotomy, retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- bassem metwally
Urolithiasis, Kidney Calculi
IAU Percutaneous Nephrolithotripsy Study
During the past 10-15 years, important advancements have been witnessed in percutaneous nephrolithotomy (PCNL) techniques and instrumentation.
- Trial name
- IAUPCNL (NCT07622238)
- Testing
- Percutaneous nephrolithotomi (PCNL)
- Where
- 2 sites in Bulgaria
- Volunteers
- 4,000 people
- Sponsor
- Foundation Endourology
Anesthesia, Intraocular Pressure
Intraocular Pressure, Optic Nerve Sheath Diameter and Optic Perfusion Pressure of Minimal Low and High-Flow Anesthesia
The aim of this clinical trial is to determine the effect of minimal low-flow versus high-flow anesthesia on intraocular pressure (IOP) by non-contact tonometry, optic nerve sheath diameter (ONSD) by USG and optic perfusion…
- Conditions
- Anesthesia, Intraocular Pressure, Nephrolithiasis
- Trial name
- NCT06684704
- Testing
- minimal and high flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Percutaneous Nephrolithotomy
Erector Spinae Plane Block for Postoperative Pain in Percutaneous Nephrolithotomy Patients: a Retrospective Study
To evaluate the ability of Erector spina Plane block decrease postoperative pain and analgesia requirements in patients undergoing Percutaneous Nephrolithotomy.
- Trial name
- NCT03897933
- Testing
- Erector Spinae Plane block ( Group I), non- blocked Group (GROUP II)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Stone, Kidney
Ultra-Mini Versus Standard Percutaneous Nephrolithotomy For Management Of Renal Calculi. A Randomized Controlled Trial.
Renal stones are one of the most common urological problems and there are multiple methods for their management such as percutaneous nephrolithotomy, mini and ultra-mini percutaneous nephrolithotomy, flexible ureteroscopy and…
- Trial name
- NCT04764071
- Testing
- percutaneous nephrolithotomy, ultra-mini percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Nephrolithiasis, Pediatric Nephrolithiasis
Tubeless vs Tube PCNL in Pediatric Nephrolithiasis
This study is designed to compare two surgical techniques for removing kidney stones in children and adolescents (ages 6-18 years).
- Trial name
- TUBELESS (NCT07183930)
- Testing
- Tubeless Percutaneous Nephrolithotomy (PCNL), Standard Tube Percutaneous Nephrolithotomy (PCNL)
- Where
- Pakistan
- Volunteers
- 640 people
- Sponsor
- Lady Reading Hospital, Pakistan
Renal Stone Disease, Kidney Calculi
The LARC Robot Simplifies Renal Access In Percutaneous Nephrolithotomy
This study is being done to evaluate a new robotic system that helps urologists more precisely reach the kidney during surgery to remove large kidney stones.
- Conditions
- Renal Stone Disease, Kidney Calculi, Refractory Kidney Stones, Kidney Stones
- Trial name
- NCT07211555
- Testing
- LARC Robotic System (Micromate™ Version 3.0)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- AdventHealth
Renal Stones
Standard Versus Mini Percutaneous Nephrolithotomy for Renal Stones
Renal stone disease is a common urological condition associated with significant morbidity. Percutaneous nephrolithotomy (PCNL) is the standard treatment for renal stones larger than 2 cm.
- Trial name
- NCT07464717
- Testing
- Mini Percutaneous Nephrolithotomy, Standard Percutaneous Nephrolithotomy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Kidney Stones, Nephrolithiasis
Retrograde Intrarenal Surgery (RIRS) With High-Power Laser and Flexible, Navigable Suction Access Sheath (FANS) vs Mini-Percutaneous Nephrolithotomy (miniPCNL) for 2-3 cm Renal Stones
This prospective cohort study aims to compare the safety and efficacy of retrograde intrarenal surgery combined with a high-power Holmium:YAG laser and flexible navigable suction access sheath versus mini-percutaneous…
- Trial name
- NCT07349992
- Testing
- Retrograde Intrarenal Surgery, Mini Percutaneous Nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Pain, Postoperative; Anesthesia, Regional
Analgesic Efficacy of Ultrasound Guided Paravertebral Block in Percutaneous Nephrolithotomy Patients
The aim of this study is to investigate the analgesic effects of thoracal paravertebral block in the patients undergoing percutaneous nephrolitotomy. Paravertebral block was applied to the study group.
- Trial name
- NCT04406012
- Testing
- paravertebral block
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Calculi, Renal, PCNL
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
A randomized controlled trial comparing the use of preoperative prophylactic single dose fosfomycin trometamol versus levofloxacin in prevention of post-PCNL infectious complications and sepsis.
- Conditions
- Calculi, Renal, PCNL, Infectious Complications
- Trial name
- NCT07355907
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Tanta University
Kidney Stone
Effects of Abdominal Cushion on PCNL in Prone Position
Percutaneous nephrolithotomy (PCNL) is the first choice for the treatment of ≥ 2cm renal stones. The positions of PCNL includes supine, prone and lateral. PCNL has been performed in my center for nearly twenty years.
- Trial name
- NCT03797027
- Testing
- Percutaneous Nephrolithotomy without an abdominal cushion, Percutaneous Nephrolithotomy with an 5 cm abdominal cushion
- Where
- China
- Volunteers
- 180 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Stone;Renal
Flexible Ureteroscopy Versus Mini-Percutaneous Nephrolithotomy for Treatment of Renal Stones
Management of nephrolithiasis is evolving rapidly, and various minimally-invasive urological procedures are currently available for treating patients with renal stones, including extracorporeal shockwave lithotripsy (ESWL)…
- Trial name
- NCT03932370
- Testing
- Flexible ureteroscopy, mini-Percutaneus nephrolithotomy
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Upper Urinary Tract Stones
Role of Nephrolithometric Scoring Systems in Prediction of PCNL Outcomes in Adult
Prospective study is to compare between different nephrolithometric scoring systems in prediction of PCNL outcomes in terms of efficacy , success rate and safety in Adult patients with UUT stones unilateral or bilateral, single…
- Trial name
- NCT04158570
- Testing
- Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University