Clinical trials: Nephrolithotomy Percutaneous
Kidney Stones
Dual Approach External Oblique Fascial Plane Block Versus Erector Spinae Plane Block for Post Operative Analgesia in Percutaneous Nephrolithotomy
Here is a patient-friendly, ClinicalTrials.gov-compliant Brief Summary written in plain language, avoiding technical jargon as much as possible while remaining accurate.
- Trial name
- BLOCK-PCNL (NCT07359391)
- Testing
- Erector Spinae Plane Block, Dual External Oblique Fascial Plane Block, General Anesthesia
- Volunteers
- 90 people
- Sponsor
- Zagazig University
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Stones, Renal Calculi > 2 cm
Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones
The investigator will compare between holmium laser setting during miniPCNL for renal stones as regard safety \& efficacy
- Trial name
- miniPCNL (NCT07393178)
- Testing
- mini percutaneous nephrolithotomy
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Urolithiasis, Kidney Stone
Standard vs Mini-PCNL for the Treatment of Stone Disease
Randomized comparison of patient outcomes following standard PCNL versus mini-PCNL.
- Conditions
- Urolithiasis, Kidney Stone, Kidney Calculi, Ureteral Calculi
- Trial name
- NCT04069013
- Testing
- PCNL
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Cleveland Clinic
Urolithiasis, Kidney Stone
Flexible Ureteroscopy With Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Renal Stones
Background: Percutaneous nephrolithotomy (PCNL) is the first-line treatment for renal stones larger than 2 cm according to EAU and AUA guidelines.
- Trial name
- NCT06526390
- Testing
- f-URS, mini-PCNL
- Where
- China
- Volunteers
- 720 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Urinary Calculi, Percutaneous Nephrolithotomy
Tubeless Percutaneous Nephrolithotomy Without Reverse Insertion of a Ureteral Catheter
Percutaneous nephrolithotomy(PCNL) is a surgical method for upper urinary calculi. The advent of tubeless PCNL (without indwelling nephrostomy tube) has been proved to be safe and effective in reducing postoperative discomfort…
- Trial name
- NCT05574517
- Testing
- Without reverse insertion of a ureteral catheter
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital of University of South China
Percutaneous Nephrolithotomy
Gram Stain of the First Urine After Puncture in Percutaneous Nephrolithotomy
In this study, investigators compared the systemic inflammatory responses after percutaneous nephrolithotomy (PCNL) patients who were given an expanded empirical antibiotic regimen based on the prediction of the possibility of…
- Trial name
- NCT06393062
- Testing
- Gram staining of the first urine after intraoperative renal puncture to predict the systemic inflammatory response after percutaneous nephrolithotomy.
- Where
- Turkey (Türkiye)
- Volunteers
- 245 people
- Sponsor
- Adiyaman University
Pain
Peritubal Infiltration of Bupivacaine in PCNL
Patients may feel significant pain at the surgery site after they wake up from the surgery. Usually pain is managed in the ward by giving strong pain medication that may slow down your mobilization and recovery process.
- Trial name
- NCT02198027
- Testing
- Bupivacaine, Normal saline infiltration
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Indus Hospital and Health Network
Urolithiasis
The Feasibility, Safety, and Efficacy of Not Indwelling of Ureteral Stents in Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is currently the preferred treatment for upper urinary tract stones larger than 2cm. In the standard PCNL procedure, a nephrostomy tube and a ureteral stent are often placed before the end of…
- Trial name
- NCT06455618
- Testing
- not Indwelling the ureteral stent, Indwelling the ureteral stent
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Urosepsis, Kidney Stone
Effect of Emergency Urinary Drainage on Subsequent PCNL Outcomes in Obstructive Urosepsis
Obstructive urolithiasis complicated by urosepsis is a life-threatening medical emergency requiring urgent urinary tract decompression.
- Trial name
- NCT07826325
- Testing
- Retrograde Ureteral Stenting followed by PCNL, Percutaneous Nephrostomy followed by PCNL
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Renal Stone
The Efficacy of Peritubal Analgesic Infiltration in Postoperative Pain Following Percutaneous Nephrolithotomy
The investigators aim to investigate the effect of peritubal local anesthetic infiltration on pain scores and analgesic consumption in patients who underwent percutaneous nephrolithotomy.
- Trial name
- NCT04160936
- Testing
- Marcaine Injectable Product
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Saddam Al Demour
Kidney Stone
Robotic-assisted Percutaneous Access
This is a first-in-man (FIM) study to show feasibility and safety profile of the newly developed robotic device for percutaneous access in PCNL surgery.
- Trial name
- NCT04435132
- Testing
- PCL under fluoroscopy with the aid of the robotic device
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- NDR Medical Technology Pte Ltd
Urolithiasis
High Supracostal Versus Subcostal Puncture in Adult PCNL
as the supra eleventh puncture PCNL is not well investigated in the literature we will conduct that randomised trial in comparison to the subcostal one
- Trial name
- NCT06350045
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Calculi
SMP vs RIRS for Symptomatic Lower Pole Renal Calculi of 10-20 mm Size: a Randomized Controlled Trial
Shock wave lithotripsy (SWL) is recommended for kidney stones < 20 mm. However, the stone clearance of lower pole calculi after SWL is limited, thus leading to an extended indication for mini-percutaneous nephrolithotripsy (PCNL)…
- Trial name
- NCT02519634
- Testing
- Super-Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Urolithiasis
Do We Really Bleed in Percutaneous Nephrolithotomy? A Single-Surgeon, Single-Center Experience
Percutaneous nephrolithotomy (PCNL) is an effective and guideline-recommended surgical technique for the treatment of large and complex renal stones; however, perioperative bleeding remains one of its most significant…
- Trial name
- NCT07360795
- Testing
- Percutaneous Nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Postoperative Pain, Nephrolithiasis
A Randomized, Double-Blind, Placebo-Controlled Trial of Anrikefon for Postoperative Analgesia After Percutaneous Nephrolithotomy
This study evaluates whether a single dose of anrikefon, given intravenously shortly before the end of kidney stone removal surgery (PCNL), can reduce opioid-related side effects such as nausea, vomiting, itching, oversedation…
- Trial name
- ARK-PCNL (NCT07825142)
- Testing
- Anrikefon
- Volunteers
- 160 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Percutaneous Nephrolithotomy
Lower Thoracic Epidural vs Erector Spinae Block for PNL
compare the efficacy of Lower Thoracic Epidural with Erector spinae plane block (ESPB) for post-operative analgesia after Percutaneous Nephrolithotomy with a hypothesis that both Lower Thoracic Epidural and Erector spinae plane…
- Trial name
- NCT05725083
- Testing
- Lower thoracic epidural, Erector spinae plane block
- Volunteers
- 42 people
- Sponsor
- Assiut University
Kidney Stones, Complex Renal Calculi
Modified Mini-PCNL Versus Standard PCNL for Complex Kidney Stones
Kidney stones that are large or complex are often treated with percutaneous nephrolithotomy, also called PCNL. Standard PCNL uses a larger access tract and is effective for removing complex kidney stones, but it may be associated…
- Trial name
- MIMIC-PCNL (NCT07697677)
- Testing
- 20 Fr Modified Mini Percutaneous Nephrolithotomy, 24 Fr Standard Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,380 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone, Surgery
Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy
The purpose of this study is to determine if adding a spinal block (medicine that will numb parts of the body to block pain) along with standard pain control at the incision site will decrease the need for narcotics for pain…
- Trial name
- NCT04663269
- Testing
- 4mg PF Dexamethasone, Control Test
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Kidney Calculi
Initial Clinical Experience With the MONARCH Platform, Urology for the Treatment of Kidney Stones
The purpose of this study is to collect descriptive performance data using the MONARCH Platform, Urology (a novel robotic device) to perform mini-percutaneous nephrolithotomy (kidney stone removal) procedures.
- Trial name
- NCT05835323
- Testing
- Robotic-assisted mini-PCNL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Auris Health, Inc.