Clinical trials: Nerve Block/Methods
Tooth Extraction Status Nos, Anesthesia, Local
Efficacy and Safety of Administration of Different Doses of 4% Articaine.
The goal of this triple-blind randomized clinical trial is to compare the efficacy and safety of administering one cartridge (1.8 mL) versus two cartridges of articaine 4% with epinephrine 1:100,000 for lower third molar…
- Trial name
- NCT06644950
- Testing
- Efficacy and safety of administering 1 or two cartridges of anesthesia
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Pain, Postoperative
Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty
Total shoulder arthroplasty (TSA) is considered to be a major surgical procedure resulting in severe postoperative pain, especially in the first 48 hours after surgery.
- Trial name
- NCT02876055
- Testing
- Single shot interscalene nerve block, Continuous interscalene nerve block, Local Infiltration Analgesia (LIA)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dental Caries
Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treatment
Objective: To compare the effectiveness and complications of intraligamentary anesthesia (ILA) with conventional inferior alveolar nerve block (IANB) during injection and dental treatment of mandibular posterior teeth.
- Trial name
- NCT04563351
- Testing
- local anaesthetic techniques
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Foot Surgery, Ankle Surgery
Liposomal Bupivacaine With Dexamethasone for Foot Surgery
This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures.
- Conditions
- Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
- Trial name
- NCT06465992
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Pain Management, Anesthesia , Analgesia
Comparison Between External Oblique Intercostal Plane Block and Rectus Sheath Block Combined With Transversus Abdominis Plane Block
Effective perioperative pain management remains a cornerstone in enhancing recovery and improving patient outcomes in laparoscopic cholecystectomy.
- Conditions
- Pain Management, Anesthesia , Analgesia, Nerve Block
- Trial name
- NCT07384000
- Testing
- External intercostal plane puncture, control group (nalbuphine), the single-puncture technique of (rectus sheath block) combined with (Transversus abdominis plane block)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Foot Surgery, Ankle Surgery
Pre-post Spinal Popliteal Block
This is a retrospective chart review to determine the non-inferiority of performing lower extremity peripheral nerve block placement under spinal anesthesia compared to its pre-spinal counterpart.
- Trial name
- NCT05354791
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Dental Anaesthesia
Intraosseous Anesthesia Versus Mandibular Nerve Block in Children
The aim of the current study is to compare a new computerized intra-osseous injection system to the conventional inferior alveolar nerve block in children
- Trial name
- NCT05193487
- Testing
- inferior alveolar nerve block, intra-osseous mandibular anaesthesia
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hernia Inguinal
Pilot Study on the Effectiveness of a TAP-block for Inguinal Hernia Repair
An prospective double blinded randomised trial,whether the use of an perioperative echoguided unilateral TAP block has an superior effect on postoperative pain after open hernia inguinal repair compared to wound infiltration with…
- Trial name
- NCT01793571
- Testing
- TAP block
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dijklander Ziekenhuis
Anesthesia, Local, Nerve Block
Lateral Sagittal vs Costoclavicular Approach for Ultrasound-Guided Infraclavicular Block
An ultrasound-guided infraclavicular block performed with the costoclavicular (CC) approach and the lateral sagittal (LS) approach will be compared in patients scheduled for forearm and hand surgery.
- Conditions
- Anesthesia, Local, Nerve Block, Brachial Plexus Block
- Trial name
- NCT04356521
- Testing
- Lateral Sagittal Approach, Costoclavicular Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pain, Postoperative, Hip Arthroplasty
CMP vs Fascia Iliaca Block
Complete motorsparing protocol (CMP) has been developed to try to minimize the motor nerve block that is created when using Facia iliaca nerve block.
- Trial name
- NCT04426058
- Testing
- CMP, Fascia Illica
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loyola University
Thoracic Surgical Procedures
Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery
Continuous paravertebral analgesia and erector spinae plane blockade (ESP) are accepted techniques at University of Pittsburgh Medical Center (UPMC) for the management of thoracic pain following surgery and trauma.
- Trial name
- NCT03758261
- Testing
- Paravertebral nerve block, Erector Spinae nerve block
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Charles Luke
Pain, Postoperative, Total Knee Arthroplasty (TKA)
Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty
Recently, several articles have suggested or reported that Adductor Canal Blocks (ACBs) offer adequate or equal analgesia and may promote better performance in early rehabilitation following Total Knee Arthroplasty (TKA) when…
- Trial name
- FemVsACB (NCT02453321)
- Testing
- Continuous Femoral Nerve Block, Nerve Block, Continuous Adductor Canal, Continuous Sciatic Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Kevin King, DO
Upper Limb Surgery
Ultrasound-guided Versus Blind Technique in Medial Brachial Cutaneous Nerve and Intercostobrachial Nerve Blocks
The axillary brachial plexus block is a technique of locoregional anesthesia indicated in the distal upper limb surgery : hand, forearm, the lower third of the arm including the elbow.
- Trial name
- ECHO_NCMB (NCT02940847)
- Testing
- medial brachial cutaneous nerve block and intercostobrachial nerve block with blind technique, medial brachial cutaneous nerve block and intercostobrachial nerve block with ultrasound-guided technique
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Transrectal Systematic Prostate Biopsy Related Pain
A Study on the Pain Control Effect of the Anesthetic Method During Prostate Biopsy: Comparison Between Pelvic Plexus Block and Periprosthetic Nerve Block
This study assesses differences in the effects of pelvic plexus block and periprostatic nerve block among various anesthetic methods that reduce the pain caused by prostate biopsy.
- Trial name
- NCT03681522
- Testing
- Pelvic plexus block, Periprostatic nerve block
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Other Acute Postoperative Pain, Pain, Postoperative
Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration
This trial is a part of the project: 'A novel technique for reliable, precise and safe postoperative pain management' (project no. 65-2014-3).
- Conditions
- Other Acute Postoperative Pain, Pain, Postoperative, Anaesthesia
- Trial name
- NCT02801799
- Testing
- Varying infusion rates of Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Anesthesia, Analgesia
Near Remote Method to Guide Performance of Regional Anesthesia
Ultrasound-guided regional anesthesia/analgesia techniques (or simply, 'regional blocks') have gained popularity as they can reduce, and sometimes even eliminate, the need for opiate analgesics (and, consequently, their side…
- Conditions
- Anesthesia, Analgesia, Nerve Block, Delivery of Healthcare
- Trial name
- NCT05968261
- Testing
- Real time 'near remote' guidance of regional blocks
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Crohn's Disease, Inflammatory Bowel Disease
A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques
Postoperative pain can pose significant challenges in the postoperative recovery of patients undergoing major colorectal surgery. Traditionally, opioids have played an important role in treating postoperative pain.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Postoperative Pain
- Trial name
- NCT02538679
- Testing
- US TAP Bupivacaine/Epinephrine, Lap TAP Bupivacaine/Epinephrine
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center