Clinical trials: Nerve Condition
Breast Cancer, Lung Cancer
Study for the Multidimensional Analyses of Resistance and Toxicity to Immune- and Targeted-therapies.
Novel treatment modalities like targeted therapies and Immune checkpoint inhibitors have revolutionised the therapeutic landscape in oncology and hematology, significantly improving outcomes even in clinical contexts in which…
- Conditions
- Breast Cancer, Lung Cancer, Melanoma, Head and Neck Cancer
- Trial name
- POSITive (NCT06321640)
- Testing
- Cohort A: primarily operable disease, candidate to adjuvant, Cohort B: locally advanced disease, Cohort C: metastatic disease
- Where
- Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Coronary Artery Disease (CAD), Obstructive Sleep Apnea (OSA)
Chemoreflex Control of Sympathetic Activity in Patients With Coronary Artery Disease
The investigators hypothesize that chemoreflex response of muscle sympathetic nerve activity (MSNA) during hypoxia and hypercapnia will be increased in coronary artery disease (CAD) patients and that the presence of obstructive…
- Trial name
- NCT02624297
- Testing
- Aerobic exercise training
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Paralysis, Unilateral, Vocal Cord
APrevent-VOIS-Implant-002 - a Two-Part, Open-Label, Non-Randomized Multicenter Study
This is a prospective, 2-part, multi-center, open-label, non-randomized clinical trial to assess safety and effectiveness of APrevent® VOIS Implants for the treatment of patients with Unilateral Vocal Fold Paralysis (UVFP).
- Trial name
- NCT05119842
- Testing
- APrevent® VOIS-Implant
- Where
- 7 sites in United States, Austria and 1 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- APrevent Biotech GmbH
Parkinson Disease (PD), MSA - Multiple System Atrophy
Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot Phase
This is an open-label, single-center Phase 1 study evaluating the safety, tolerability, and test-retest characteristics of [11C]MODAG-005, an investigational positron emission tomography/computed tomography (PET/CT) radioligand…
- Conditions
- Parkinson Disease (PD), MSA - Multiple System Atrophy, Healthy Adult Participants
- Trial name
- PIOSA (NCT07640542)
- Testing
- [11C]MODAG-005
- Where
- Germany
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- MODAG GmbH
Carpal Tunnel Syndrome, Psoriatic Arthritis
Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis; Ultrasonography and Magnetic Resonance Imaging Findings
This study aimed to investigate relationship between CTS diagnosis with electrodiagnostic studies and median nerve's cross-sectional area measered by US and MRI in PsA patients.
- Trial name
- NCT05086042
- Testing
- Ultrasonography, Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Nerve Disorders
The Use of i/t Curve in Assessment of Phototherapy Effects
Conventional electrodiagnostic examination is useful in daily physiotherapeutic practice. Nevertheless, the subjective assessment of muscle contraction and perceived current vibrations carries the risk of error and thus is a…
- Trial name
- NCT02618642
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Carpal Tunnel Syndrome
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02696161
- Testing
- platelet rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Normal Tension Glaucoma
Autonomic Nervous System Activity and Normal Tension Glaucoma
Evidence has accumulated that systemic and ocular mechanisms, responsible for regulating blood flow in the area of the optic disc, such as reduced ocular perfusion pressure, abnormal autoregulation and vascular dysregulation may…
- Trial name
- ANS (NCT01192061)
- Where
- Poland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Melanoma
The Impact of a Prevention Program on Sun Risks in Primary School in Tropical French Region
Sun exposure during childhood can cause the development of skin cancer in later years, in particular melanoma, which is the most lethal.The worldwide incidence of melanoma is on the rise, with nearly 290,000 new cases diagnosed…
- Trial name
- PRESOLRE (NCT05367180)
- Testing
- MISOLRE prevention program on sun risks, "Vivre avec le Soleil" prevention program on sun risks, Sun protection equipment
- Where
- Reunion
- Volunteers
- 1,452 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pulpitis
Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis
Ninety patients with irreversible pulpitis diagnostic will participate in this clinical study. The participants will be divided into 2 groups of 45 patients, who will receive the inferior alveolar nerve block injections of 1.8 mL…
- Trial name
- Volumes (NCT02422823)
- Testing
- Articaine, Epinephrine
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isabel Peixoto Tortamano
Cutaneous Melanoma, Melanocytic Nevus
MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma
This trial studies how well MoleMapper, Visiomed, and confocal microscopy work in screening participants for melanoma. Analyzing images (photographs) made with three different portable imaging systems may be as good as a visit to…
- Conditions
- Cutaneous Melanoma, Melanocytic Nevus, Skin Carcinoma
- Trial name
- NCT03699995
- Testing
- Confocal Microscopy, Dermoscopy, Imaging Procedure
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Fatigue, Walking, Difficulty
Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS
Transcutaneous Electrical Nerve Stimulation (TENS) is a treatment that could potentially reduce walking problems and fatigue in persons with Multiple Sclerosis.
- Conditions
- Fatigue, Walking, Difficulty, Multiple Sclerosis
- Trial name
- NCT06432686
- Testing
- Transcutaneous Electrical Nerve Stimulation, Movement
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Melanoma
Skin Self-Examination Education During Mammography
The skin self-examination for melanoma (SSE) educational materials were developed with the input provided by women undergoing screening mammograms.
- Trial name
- SSE (NCT03512457)
- Testing
- Minimal Intervention, Intensive Intervention
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Melanoma
Evaluation of Pigmented Skin Lesions With MelaFind(R) System
The purpose of this clinical trial is to demonstrate that MelaFind®, a new instrument that uses machine vision for non-invasive early detection of cutaneous pigmented malignant melanoma, is safe and effective.
- Trial name
- NCT00434057
- Testing
- MelaFind(R)
- Where
- 2 sites in United States
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- MELA Sciences, Inc.
Glaucoma
Barcelona Esquerra Glaucoma Artificial Intelligence-based Screening Program (BEGAS)
Two primary care-based screening systems will be tested to identify subjects with referrable glaucoma to hospital care. Subjects between 45 to 64 years old living in the metropolitan area of Barcelona will be invited to…
- Trial name
- BEGAS (NCT06353542)
- Testing
- Software analysis, Ophthalmologist examination
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Parkinson Disease Dementia, Parkinson Disease
Community Outreach for Palliative Engagement -- Parkinson Disease
The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartners with Parkinson's disease and Lewy Body…
- Conditions
- Parkinson Disease Dementia, Parkinson Disease, Parkinson's Disease and Parkinsonism, Lewy Body Parkinsonism
- Trial name
- COPE-PD (NCT05222386)
- Testing
- Parkinson Disease Standard Care, Online Community-Supported Palliative Care
- Where
- United States
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Postoperative Cognitive Impairment, Optic Nerve Sheath Edema
Effect of Different Ventilation Modes on POCD in Elderly Patients with Abdominal Wall Hernia
The purpose of this clinical trial is to understand the effect of different ventilation patterns during surgery on postoperative cognitive impairment in elderly patients with abdominal wall hernias.
- Trial name
- NCT06764745
- Testing
- PC Ventilation Modes, VC Ventilation Modes, PRVC Ventilation Modes
- Where
- China
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia University of Science and Technology
Spinocerebellar Ataxia
Neuromuscular Electrical Stimulation on Median Nerve Facilitates Low Motor Cortex Excitability in Human With Spinocerebellar Ataxia
Spinocerebellar ataxia (SCA) is a hereditary disorder with movement incoordination. The ataxia performed low intra-cortical facilitation mainly due to the degenerative cerebellum.
- Trial name
- NCT02103075
- Testing
- Neuromuscular electrical stimulation
- Where
- Taiwan
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Carpal Tunnel Syndrome
Role of Ultrasonography in the Diagnosis of Carpal Tunnel Syndrome
This prospective study aims to evaluate the median nerve in Carpal Tunnel Syndrome by high-frequency ultrasound and color Doppler in comparison with clinical and Nerve conduction studies.
- Trial name
- NCT04976998
- Testing
- imaging
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Carpal Tunnel Syndrome
Correlation Between Palmaris Longus Muscle and Carpel Tunnel Syndrome
The Palmaris longus (PL) muscle is a long, adaptable muscle that lies between the Flexor Carpi Ulnaris and Flexor Carpi Radialis muscles in the shallow volar segment of the lower arm.
- Trial name
- NCT05578963
- Testing
- Schaeffer's Test for palmaris tendon
- Where
- Pakistan
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Bahria University
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