Clinical trials: Nerve Condition
Glaucoma, Tomography, Optical Coherence
The Diagnostic Performance of BMO-MRW and RNFL Thickness and Their Combinational Index Using Artificial Neural Network
This study evaluates the relationship between BMO-MRW and RNFL thickness measured by OCT. SD-OCT exam will be performed to all patients in this study.
- Trial name
- NCT03257020
- Testing
- SD-OCT
- Where
- South Korea
- Volunteers
- 402 people
- Sponsor
- Pusan National University Hospital
Lumbar Radiculopathy
Ultrasound Versus Fluoroscopy-guided Selective Lumbar Nerve Root Injection
The study is conducted to compare pain relief, accuracy and safety and radiation exposure of selective lumbar nerve root injection for lumbar radicular pain using ultrasound guidance versus fluoroscopy guidance
- Trial name
- NCT05290779
- Testing
- selective lumbar nerve root injection
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Minia University
Solid Tumor, TNBC - Triple-Negative Breast Cancer
TH1902 in Patients With Advanced Solid Tumors
Open label first-in-human study of TH1902 in solid cancer, with 4 sequential parts: Part 1 (dose escalation): patients with recurrent advanced solid tumors (all comers) that have relapsed or are refractory to standard…
- Conditions
- Solid Tumor, TNBC - Triple-Negative Breast Cancer, Hormone Receptor-positive Breast Cancer, Epithelial Ovarian Cancer
- Trial name
- NCT04706962
- Testing
- TH1902
- Where
- 6 sites in United States, Canada
- Volunteers
- 70 people
- Sponsor
- Theratechnologies
Recurrent Melanoma, Stage III Melanoma
Tanespimycin in Treating Patients With Stage III-IV Melanoma
This phase II trial is studying how well tanespimycin works in treating patients with stage III or stage IV melanoma. Antitumor antibiotics such as tanespimycin may stop the growth of melanoma by stopping blood flow to the tumor.
- Conditions
- Recurrent Melanoma, Stage III Melanoma, Stage IV Melanoma
- Trial name
- NCT00087386
- Testing
- tanespimycin, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Analgesia
Analgesia After Total Knee Arthroplasty
The recovery from knee replacement surgery often involves a significant amount of pain. The best way to prevent/treat this pain is unknown.
- Trial name
- NCT00869037
- Testing
- Periarticular Injection, CFNB + Posterior Capsular Injection
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
Carpal Tunnel Syndrome (CTS)
Reliability and Validity of Hand Function Tests in Carpal Tunnel Syndrome
Carpal tunnel syndrome is a condition that causes numbness, tingling, and weakness in the hand due to pressure on the median nerve in the wrist.
- Trial name
- NCT07706296
- Testing
- Standardized Hand Function and Dexterity Testing
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Bakircay University
Carpal Tunnel Syndrome, Pregnancy Related
The Effect of Splints in Pregnant Women With Carpal Tunnel Syndrome
It is aimed to compare the effect of two different splints on carpal tunnel syndrome in pregnant individuals after 4 weeks of use.
- Conditions
- Carpal Tunnel Syndrome, Pregnancy Related, Splints
- Trial name
- NCT06131996
- Testing
- Volar supported splint, elastic splint
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Mardin Artuklu University
Melanoma (Skin)
Patient-led Surveillance Compared to Clinician-led Surveillance in People Treated for Localised Melanoma.
The purpose of this pilot study is to evaluate digitally supported skin self-examination compared to usual care in people treated for localised melanoma.
- Trial name
- MEL-SELF (NCT03581188)
- Testing
- Patient-led surveillance, Clinician-led surveillance
- Where
- 3 sites in Australia
- Volunteers
- 100 people
- Sponsor
- University of Sydney
Solid Tumors
Expanded Access Program for Avapritinib
This record comprises the currently available Expanded Access Programs (EAP) for avapritinib (BLU-285): 1) A Post Trial Access (PTA) program to provide continued access to treatment with avapritinib to BLU-285-1107 participants…
- Trial name
- NCT04714086
- Testing
- Avapritinib
- Sponsor
- Blueprint Medicines Corporation
Piriformis Syndrome, Exercise Training
Telerehabilitation vs. Home Exercise in Piriformis Syndrome: A Comparative Study
The aim of this study is to compare the effects of asynchronous telerehabilitation and home exercise programs on pain, fear of pain, functionality, and performance in individuals with piriformis syndrome.
- Conditions
- Piriformis Syndrome, Exercise Training, Telerehabilitation
- Trial name
- PIRI-REHAB (NCT07502573)
- Testing
- Home exercise programme, telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Appendectomy, Laparoscopic, Pediatric Anesthesia
Rectus Sheath Block and Local Wound Infiltration in Pediatric Laparoscopic Appendectomies
Laparoscopic appendectomy surgeries are among the most commonly performed procedures in childhood. However, they are associated with moderate to severe postoperative pain.
- Conditions
- Appendectomy, Laparoscopic, Pediatric Anesthesia, Nerve Block/Methods, Regional Anesthesia
- Trial name
- NCT06913205
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Bursa City Hospital
Total Hip Replacement, Pericapsular Nerve Group Bloc
Effect of Pericapsular Nerve Group Block on Postoperative Cognitive Function
The aim of this study was to examine the effect of pericapsular nerve group (PENG) block, which is frequently applied for postoperative analgesia in total hip replacement surgeries performed under spinal anesthesia, on…
- Conditions
- Total Hip Replacement, Pericapsular Nerve Group Bloc, Postoperative Cognitive Dysfunction
- Trial name
- NCT06736405
- Testing
- Pericapsular nerve group block, No Pericapsular nerve group block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Melanoma (Skin)
Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma
RATIONALE: Vaccines made from a patient's dendritic cells and tumor cells may make the body build an immune response to kill tumor cells.
- Trial name
- NCT00085488
- Testing
- autologous tumor cell vaccine, therapeutic autologous dendritic cells
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Glaucoma
The Effectiveness Of Home-Based Circuit Training On Eye Pressure And Eye Nerve Structures In Patients With Glaucoma
The goal of this randomised control trial is to learn about the effect of home based circuit training on patients with primary glaucoma. The main questions to answer are: 1.
- Trial name
- NCT07733388
- Testing
- Home-Based Circuit Training
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- Universiti Sains Malaysia
Thoracic Outlet Syndrome
Electromyography in Thoracic Outlet Syndrome
Record the ENMG data carried out systematically in patients treated by rehabilitation for thoracic outlet syndrome in order to assess their characteristics and judge the relevance of these data in the context of the diagnosis and…
- Trial name
- ENMG-AFC (NCT05360303)
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Nantes University Hospital
Brain Neoplasms, Malignant, Brain Neoplasms, Benign
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
RATIONALE: Pioglitazone hydrochloride may be effective treatment for cognitive dysfunction caused by radiation therapy. PURPOSE: This phase I trial is studying the side effects and best dose of pioglitazone hydrochloride in…
- Conditions
- Brain Neoplasms, Malignant, Brain Neoplasms, Benign, Malignant Meningioma, Glioblastoma Multiforme
- Trial name
- NCT01151670
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
TURBT
Application of Pericapsular Nerve Group (PENG) Block
This study aims to determine the efficacy and safety of the Pericapsular Nerve Group (PENG) block in preventing obturator nerve reflex during transurethral resection of bladder tumors.
- Trial name
- NCT07078773
- Testing
- peng block, obturator nerve block
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Head and Neck Cancer, Islet Cell Tumor
Internal Radiation Therapy in Treating Patients With Liver Metastases From Neuroendocrine Tumors
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Conditions
- Head and Neck Cancer, Islet Cell Tumor, Metastatic Cancer, Pheochromocytoma
- Trial name
- NCT00466856
- Testing
- octreotide acetate, yttrium Y 90 resin microspheres
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Vagus Nerve Stimulation
Transauricular Vagus Nerve Stimulation Improves Postoperative Sleep Disorders in Elderly Patients.
Postoperative sleep disorder is one of the common complications after general anesthesia. Compared to patients of various ages, elderly patients have a much higher incidence of postoperative sleep disturbance.
- Trial name
- Vnstep (NCT06421051)
- Testing
- Transauricular Vagal Nerve Stimulation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Beijing Tiantan Hospital
Solid Tumors Harboring NTRK Fusion
A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
This research study is done to test how well different types of cancer respond to the drug called larotrectinib. The cancer must have a change in a particular gene (NTRK1, NTRK2 or NTRK3).
- Trial name
- NAVIGATE (NCT02576431)
- Testing
- BAY2757556 (Larotrectinib, Vitrakvi)
- Where
- 98 sites in United States, Argentina and 23 more
- Volunteers
- 215 people
- Sponsor
- Bayer
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