Clinical trials: Nerve Condition
Vagus Nerve Autonomic Disorder, Heart Rate
Balance, Autonomic Response, and Sensory Modulation to Dosage of Mechanical Vagal Stimulation in Healthy Adults
The vagus nerve (VN) plays a crucial role in regulating vital functions (heart rate, blood pressure, digestion, and immune response) and maintaining communication between internal organs and the brain.
- Conditions
- Vagus Nerve Autonomic Disorder, Heart Rate, Pain, Equilibrium; Disorder, Labyrinth
- Trial name
- BARVANS (NCT06541808)
- Testing
- mechanical Vagus Nerve Stimulation (Low Intensity), mechanical Vagus Nerve Stimulation (Intermediate Intensity), mechanical Vagus Nerve Stimulation (High Intensity)
- Where
- Austria
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Non-Small Cell Lung Cancer, Metastatic Melanoma
A Study to Investigate 14C-bemcentinib in Healthy Male Subjects
The aims of this Study were to determine: How much of the Study Drug (bemcentinib) ends up in urine and faeces How much of the Study Drug and its breakdown products get into the bloodstream The breakdown products (metabolites) of…
- Conditions
- Non-Small Cell Lung Cancer, Metastatic Melanoma, Acute Myeloid Leukemia, Myelodysplastic Syndromes
- Trial name
- 8479217 (NCT06469138)
- Testing
- Bemcentinib
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- BerGenBio ASA
Pain
Exparel Infiltration in Anterior Cruciate Ligament Reconstruction
This is a randomized, single blinded, standard of care controlled clinical trial. All adult patients over sixteen desiring anterior cruciate ligament reconstruction will be eligible.
- Trial name
- NCT02606448
- Testing
- Liposomal bupivacaine, Femoral nerve block, Ropivacaine
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Epilepsy, Temporal Lobe, Temporal Lobe
Light Scattering Spectroscopy to Determine Brain Tumors
This study will use light scattering spectroscopy (LSS) to analyze brain tissue removed from patients during brain surgery to determine if this new technology can be used to differentiate between normal and cancerous cells.
- Trial name
- NCT00067418
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Symptomatic Irreversible Pulpitis
Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars
Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis.
- Trial name
- NCT03117491
- Testing
- GGNB injections, IANB injections, GGNB + IANB injections
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Pain, Acute
Antinociceptive Effect of Transauricular Electrical Vagal Nerve Stimulation
This investigation is going to study whether electrical tVNS applied at the cymba of auricular conchae reduces central sensitization of experimentally induced pain in comparison with electrical sham stimulation applied at the…
- Trial name
- TVNS_TSP (NCT04448990)
- Testing
- TENS eco 2 Transauricular vagal nerve stimulation
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Neurofibromatosis Type 1, Tumors of the Central Nervous System
Stem Cells in NF1 Patients With Tumors of the Central Nervous System
Objectives 1. Establish an induced pluripotent stem cell (iPSC) bank for phenotypically well-characterized patients with NF1. 2.
- Trial name
- NCT03332030
- Testing
- Collection of Stem Cells
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Roger Packer
Anesthesia, Postoperative Pain
The Effect of Ultrasound-guided Erector Spinae Block and Intraoperative Intercostal Nerve Block on Postoperative Analgesia in Thoracic Surgery
This study aims to compare the effect of ultrasound-guided erector spinae plane block and interthoracic intercostal nerve block in thoracic surgery.
- Conditions
- Anesthesia, Postoperative Pain, Ultrasound Therapy; Complications
- Trial name
- NCT04581616
- Testing
- Intrathoracic Intercostal Nerve Block, Erector Spinae Plane Block
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postural Tachycardia Syndrome
Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
This study is being conducted to see how people with Postural tachycardia syndrome (POTS) make sense of the things they see. The information may help doctors to learn more about how the different parts of people's brains…
- Trial name
- NCT05618054
- Testing
- Looming task
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Carpal Tunnel Syndrome
Ultrasound Analysis of Human Carpal Tunnel System
This study evaluates the ability of ultrasound to measure the movement of tendons and nerves within the human carpal tunnel.
- Trial name
- NCT02747836
- Testing
- Ultrasound of the wrist
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alzheimer's Disease, Mild Cognitive Impairment
[18F]THK-5351 Positron Emission Computed Tomography Study of Normal, Mild Cognitive Impairment, Alzheimer's Disease and Other Neurodegenerative Disease
This is a cross-sectional and longitudinal study to evaluate the clinical utility of [18F]THK-5351 positron emission computed tomography in cognitively healthy volunteers, mild cognitive impairment (MCI), Alzheimer's disease (AD)…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Neurodegenerative Diseases
- Trial name
- NCT02656498
- Testing
- [18F]THK-5351
- Where
- 2 sites in South Korea
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Jae Seung Kim
Ovarian Cancer, Cervical Cancer
Ensuring Communication in Hospice by Oncology Study (ECHO)
The goal of this study is to determine if scheduled communication with the oncology team through phone calls is helpful to caregivers with the transition to hospice care.
- Conditions
- Ovarian Cancer, Cervical Cancer, Uterine Cancer, Head and Neck Cancer
- Trial name
- NCT02069769
- Testing
- communication with oncology team
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ann Arbor Stage I Lymphoma, Ann Arbor Stage II Lymphoma
- Trial name
- NCT05334069
- Testing
- Questionnaire Administration, Biospecimen Collection
- Where
- 751 sites in United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Preeclampsia, Intracranial Pressure Increase
Assessment of Optic Nerve Sheath Diameter in Preeclamptic Pregnant Women Using Ultrasonography and Anesthetic Management
Preeclampsia is a serious condition associated with complications such as pulmonary edema, placental abruption, hemolysis, thrombocytopenia, and cardiac, renal, and neurological complications, occurring at a rate of 2.7-8% in…
- Conditions
- Preeclampsia, Intracranial Pressure Increase, Pregnancy; Anesthesia, Adverse Effect, Central Nervous System
- Trial name
- NCT06522295
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Atherosclerosis Cardiovascular Disease, Obesity
Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.
This study aims to investigate how moderate wine consumption influences circulating extracellular vesicles (EVs) in healthy adults.
- Conditions
- Atherosclerosis Cardiovascular Disease, Obesity, Metabolic Syndrome, Metabolic Disorders
- Trial name
- (WINEVOME) (NCT07361887)
- Testing
- White Wine, Red Wine, Water
- Where
- Spain
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Seville
Strabismus, Exotropia
Validation of a Smartphone-based Intelligent Diagnosis and Measurement for Strabismus
The current measurement methods of strabismus include the corneal light reflection method, prism alternate covering, etc., which especially rely on the subjective experience of doctors, and there is a large error between…
- Conditions
- Strabismus, Exotropia, Esotropia, Vertical Strabismus
- Trial name
- NCT05615519
- Testing
- A new technology based on 3D reconstruction and deep learning algorithm to achieve an automatic diagnosis of strabismus based on patient-sourced videos of programmatic cover tests.
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Musculoskeletal Diseases, Median Nerve Disease
The Relationship Between Ultrasonographic Findings and Sleep Quality in Carpal Tunnel Syndrome
The aim of our study is to determine the relationship between disease severity and sleep quality in CTS patients and to compare the findings with healthy controls.
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound
- Trial name
- NCT05742776
- Testing
- Assessment of Sleep Quality
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Optic Neuritis
Pupillometry Dynamic Measures in Patients Without Ocular or Neurological Disease
Retrobulbar optic neuritis (NORB) is the damage to the optic nerve caused by inflammation. It causes a rapidly progressive and painful visual loss, often among young subjects.
- Trial name
- PCT (NCT02894281)
- Testing
- pupillary light reflex
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Problem With Vision Blindness, Intraocular Pressure
Intraocular Pressure During Abdominal Aortic Aneurysm (AAA) Repair
The objective of this study will be to answer a clinical question that has not already been investigated; that is, what are the effects of aortic infra-renal clamping and unclamping on intraocular pressure during Abdominal Aortic…
- Conditions
- Problem With Vision Blindness, Intraocular Pressure, Ischemic Optic Neuropathy
- Trial name
- NCT00450294
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Trigeminal Neuralgia
Trigeminal Neuralgia Electrophysiology
The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia.
- Trial name
- NCT05269472
- Testing
- Trigeminal Electrophysiology
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.