Clinical trials: Nerve Condition
Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma
Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions
This laboratory study is looking at genes in participants with neuroblastoma or noncancerous conditions. Identifying genes related to cancer may help in the study of cancer.
- Conditions
- Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Recurrent Neuroblastoma, Regional Neuroblastoma
- Trial name
- NCT00436696
- Testing
- Laboratory Biomarker Analysis
- Where
- 2 sites in United States
- Volunteers
- 9,350 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Carpal Tunnel Syndrome, Trigger Finger
Tourniquet vs. No Tourniquet for Carpal Tunnel and Trigger Finger Release
Background: Trigger finger and carpal tunnel syndrome are two of the most common conditions treated by the hand surgeon. During these procedures, a tourniquet is often used to minimize bleeding and improve visualization of the…
- Trial name
- NCT04354415
- Testing
- Carpal tunnel or trigger finger release
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Melanoma
Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma
Evaluate the antitumor activity of hu14.18-IL2 in the minimal residual disease setting. Evaluate the time to recurrence and overall survival of patients treated with hu14.18-IL2.
- Trial name
- NCT00590824
- Testing
- hu14.18-IL2
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Wisconsin, Madison
Prader-Willi Syndrome
Study of Emotion and Cognition Abilities of Children With PWS and Proposition of an Innovative Remediation
The present project project is divided in two parts. The primary aim of the part 1 of this study is to evaluate emotional control abilities of children with Prader-Willi syndrome (PWS) aged from 9 to 15 years and to study…
- Trial name
- PRACOM1 (NCT04526379)
- Testing
- Questionnaires, t-VNS
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Piriformis Syndrome
Kinesio Taping Technique and Trigger Point
Kinesio taping is a novel method which recently has emerged as a viable option to treat of various musculoskeletal and neuromuscular deficits.
- Trial name
- KT (NCT01752179)
- Testing
- kinesio Tape : Width 5cm ,Length 35cm Y shape
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Postoperative Pain, Knee Surgery
Comparison of Nerve Blocks for Pain Relief After Knee Surgery
This retrospective observational study compares the postoperative analgesic effectiveness of ultrasound-guided fascia iliaca compartment block (FICB) with combined IPACK and genicular nerve block (GNB) in patients undergoing knee…
- Trial name
- NCT07845591
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block, Ultrasound-Guided Combined IPACK and Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Gaziantep
Carpal Tunnel Syndrome
Assessment of Ultrasound Findings, Nerve Test Results, and Hand Function in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome is one of the most common conditions caused by compression of a nerve at the wrist. It can lead to numbness, tingling, pain, weakness, and difficulty performing daily activities.
- Trial name
- NCT07752797
- Testing
- Ultrasonographic and Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Bladder Cancer
COMPARISON OF OBTURATOR NERVE BLOCK TECHNIQUES IN TURBT
Bladder cancer is one of the most common cancers in older adults. The standard treatment for many bladder tumors is a surgical procedure called transurethral resection of bladder tumor (TUR-BT).
- Trial name
- NCT07481123
- Testing
- Subpectineal Obturator Nerve Block, Interfacial Obturator Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yavuz Saygılı
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
Aquarius Pilot Study to Evaluate the New Axonics Trial System
Evaluation of the new Axonics External Trial System (ETS-02) in patients with overactive bladder (OAB) and/or fecal incontinence (FI).
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI), Overactive Bladder (OAB)
- Trial name
- NCT07335484
- Testing
- Axonics External Trial System (ETS)
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people
- Sponsor
- Axonics, Inc.
Malignant Melanoma Stage III
Optimal Neo-adjuvant Combination Scheme of Ipilimumab and Nivolumab
This is an open-label three-arm phase 2 trial (including a Simon stage 2 design) consisting of 90 stage III melanoma patients randomized 1:1:1 to receive either 2 courses 3 mg/kg ipilimumab + 1 mg/kg nivolumab every 3 weeks (Arm…
- Trial name
- OpACIN-neo (NCT02977052)
- Testing
- Ipilimumab, Nivolumab, Surgery
- Where
- 4 sites in Australia, Austria and 2 more
- Volunteers
- 186 people
- Sponsor
- The Netherlands Cancer Institute
Brain and Central Nervous System Tumors
Carmustine and O(6)-Benzylguanine in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. O(6)-benzylguanine may increase the effectiveness of carmustine by making tumor cells more sensitive to the…
- Trial name
- NCT00046878
- Testing
- O6-benzylguanine, carmustine
- Sponsor
- Duke University
Renal Cell Carcinoma, Melanoma
REduced Frequency ImmuNE Checkpoint Inhibition in Cancers
The REFINE trial aims to asses whether giving an immunotherapy drug less-often to patients with advanced cancer, results in fewer side effects whilst continuing to be an effective treatment.
- Trial name
- REFINE (NCT04913025)
- Testing
- Nivolumab, Pembrolizumab
- Where
- 3 sites in United Kingdom
- Volunteers
- 160 people
- Sponsor
- University College, London
Carpal Tunnel Syndrome
Combined Manual Therapy and Percutaneous Neuromodulation for Moderate Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy and can cause pain, numbness, tingling, and functional impairment of the hand.
- Trial name
- MANUCTS (NCT07654621)
- Testing
- Combined Manual Therapy and Ultrasound-Guided Percutaneous Neuromodulation, Postsurgical Rehabilitation
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad Europea de Valencia
Stage IV Melanoma, Stage III Melanoma
Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma
This is a Phase I/Ib investigator-initiated open label of the combination of VESANOID and pembrolizumab treatment.
- Conditions
- Stage IV Melanoma, Stage III Melanoma, Advanced Melanoma
- Trial name
- NCT03200847
- Testing
- Pembrolizumab with All-Trans Retinoic Acid
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Phantom Limb, Leg Amputation
Leg Amputation and Continuous Sciatic Nerve Block
Analgesia following leg amputation is based on morphine administration. For elderly patients of ASA physical status 2 or 3, morphine sparing is possible when perinervous block techniques are used.
- Trial name
- CAPDAF (NCT00427947)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Bordeaux
Melanoma, Breast Cancer
Contrast-enhanced Ultrasound for Sentinel Node Detection
This is a prospective single-center interventional non-inferiority study where subjects are participating for one day for patients 18 years or older with melanoma, breast cancer or head \& neck cancer (including melanoma of head…
- Conditions
- Melanoma, Breast Cancer, Head & Neck Cancer
- Trial name
- NCT07310758
- Testing
- Sonazoid
- Where
- Netherlands
- Volunteers
- 91 people
- Sponsor
- The Netherlands Cancer Institute
Non Small Cell Lung Cancer, Advanced Solid Tumor
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single agent and in combination with pembrolizumab in…
- Conditions
- Non Small Cell Lung Cancer, Advanced Solid Tumor, Metastatic Melanoma, Metastatic Head and Neck Carcinoma
- Trial name
- PRESERVE-001 (NCT04140526)
- Testing
- ONC-392, Pembrolizumab, Docetaxel
- Where
- 37 sites in United States, Australia
- Volunteers
- 733 people
- Sponsor
- OncoC4, Inc.
Cerebral Stroke, Cerebral Venous Thrombosis
Intracranial Hypertension and Optic Nerve Sheath Diameter
Intracranial hypertension (ICH) is a mortality risk factor in severe traumatic brain injury (TBI), in purulent meningitis, in hepatic encephalopathy and in Reye's syndrome.
- Trial name
- DENO (NCT01796015)
- Testing
- ONSD ultrasound
- Where
- 2 sites in France
- Volunteers
- 230 people
- Sponsor
- Hospices Civils de Lyon
Stroke, Hypertension
Renal Denervation Hypertension After Stroke
It is known, that hypertension is the major risk factor of stroke and recurrent stroke. Blood pressure reduction - together with antithrombotics - remain crucial in stroke prevention.
- Trial name
- REHEARSE (NCT01689415)
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Bispebjerg Hospital
Melanoma
A Study of HX008 for the Treatment of Patients With Malignant Melanoma
HX008 is a humanized monoclonal antibody targeting PD-1 on T cell surface, restores T cell activity, thus enhancing immune response and has potential to treat various types of tumors.
- Trial name
- NCT04749485
- Testing
- HX008
- Where
- 11 sites in China
- Volunteers
- 119 people
- Sponsor
- Taizhou Hanzhong biomedical co. LTD
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.