Clinical trials: Nerve Condition
Fibromyalgia
Occipital Nerve Stimulation in Fibromyalgia
The aim of this study is to investigate whether greater occipital nerve stimulation is effective in the treatment of fibromyalgia related pain.
- Trial name
- NCT00917176
- Testing
- Occipital nerve stimulation
- Where
- Belgium
- Sponsor
- University Hospital, Antwerp
Cranial Nerve Palsy
Cranial Nerves Tractography
Introduction: The skull base tumors surgery remains a challenge since numerous cranial nerves or vessels closely surround them. Recently, diffusion tensor imaging has developed with the tractography following white fibers and…
- Trial name
- CN Tracto (NCT02978911)
- Testing
- preoperative cerebral MRI and operative findings
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hospices Civils de Lyon
Intercostal Nerve Block, Cryo Analgesia
Cryo Nerve Block Trial
Background: Minimally invasive lung surgery, such as video-assisted thoracoscopic surgery (VATS) or robot-assisted thoracoscopic surgery (RATS), has become more common for lung resections because it leads to faster recovery, less…
- Conditions
- Intercostal Nerve Block, Cryo Analgesia, Minimally Invasive Lung Surgery
- Trial name
- NCT06861387
- Testing
- Cryotherapy, PAiN - multimodal analgesia
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- St. Antonius Hospital
Malignant Carcinoid Syndrome
Comparison of Lanreotide Autogel® and Sandostatin LAR Depot in the Treatment of Clinical Symptoms Associated With Carcinoid Syndrome
The aim of this study is to compare the efficacy and safety of lanreotide Autogel and Sandostatin LAR Depot, to see whether these two 28-day prolonged release formulations produce a similar clinical response in patients with…
- Trial name
- NCT00092287
- Testing
- lanreotide Autogel (somatostatin analogue), Sandostatin long acting release (LAR) Depot (somatostatin analogue)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ipsen
Fecal Incontinence, Bowel Incontinence
Fecal Incontinence Treatment (FIT) Study
Patients with severe fecal incontinence (FI), defined as two or more episodes of staining, solid or liquid FI per week, and who meet the inclusion criteria for Injection of Solesta (INJ; an inert bulking agent), or Biofeedback…
- Trial name
- NCT03811821
- Testing
- Biofeedback, Injection
- Where
- 6 sites in United States
- Volunteers
- 275 people
- Sponsor
- Mayo Clinic
Migraine
Multicenter, Double-blind, and Randomized Controlled Trial of Ultra-Distal TENS Device for Migraine Treatment
Multicenter, double-blind, and randomized controlled trial of Ultra-Distal Transcutaneous Electrical Nerve Stimulation (TENS) Device for Migraine treatment.
- Trial name
- NCT07451158
- Testing
- Trail of Ultral-distal Transcutaneous Electrical Nerve Stimulation, Fake Stimulus
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Healthy Volunteer, Prostate Cancer
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors
Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes.
- Conditions
- Healthy Volunteer, Prostate Cancer, Head and Neck Cancer, Esophageal Cancer
- Trial name
- NCT04354064
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Mandibular Fractures, Fracture in Mental Nerve Region
Evaluation of Modified Omega Plate in the Management of Mandibular Fractures Compared With Conventional Fixation
Twelve adult patients with mandibular fractures in the mental region were enrolled and randomly divided into two equal groups. Group I received fixation using custom-designed modified omega bone plates, while Group II was treated…
- Trial name
- COMET-OMF (NCT07206134)
- Testing
- Modified Omega bone plate for fixation of mandibular fractures in mental foramen region, Conventional miniplates for fixation of mandibular fractures
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Tanta University
Type 2 Diabetes
Percutaneous CT-guided Cryoablation of the Splanchnic Nerves
The purpose of this study is to evaluate the safety and effectiveness of freezing (cryoablation) of the splanchnic nerve for management of diabetes.
- Trial name
- NCT04569721
- Testing
- CT Guided Splanchnic Cryoablation
- Where
- United States
- Sponsor
- Emory University
Unrecognized Condition
The Influence of Rhythm, Cognitive Task and Physical Activity on the Cardiac ANS in Chronic Stroke Patients
Autonomic dysfunction is a common complication of stroke that may lead to poor rehabilitation outcomes and to increase in mortality.
- Trial name
- NCT03016416
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Trigeminal Neuralgia, Temporomandibular Disorder
Comorbid Painful TMD Among Trigeminal Neuralgia
An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.
- Conditions
- Trigeminal Neuralgia, Temporomandibular Disorder, Myofascial Pain, Trigeminal Neuropathy
- Trial name
- TNTMD (NCT05914558)
- Testing
- Clinical appointment
- Where
- 2 sites in United States
- Sponsor
- University of Minnesota
Large Vessel Occlusion, Acute Ischemic Stroke
Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke
This is a randomized open-label, with blinded outcome pilot study to evaluate the effect on inflammatory and brain injury laboratory values and explore clinical outcomes in patients who present with ischemic strokes due to large…
- Trial name
- NUVISTA2 (NCT07404852)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Washington University School of Medicine
Meralgia Paresthetica
Conservative Treatment and Ultrasound Guided Injection for Treatment Meralgia Paresthetica
Meralgia paresthetica (MP) is an entrapment mononeuropathy of the lateral femoral cutaneous nerve (LFCN), where conservative treatment options are not always sufficient.
- Trial name
- NCT04004052
- Testing
- Ultrasound guided injection, Transcutaneous Electrical Nerve Stimulation (TENS)
- Volunteers
- 54 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Bell Palsy
Effects of Massage Therapy and Facial PNF in Early Bell's Palsy
Effects of Massage therapy and Facial PNF in early Bell's palsy
- Trial name
- NCT05679752
- Testing
- Facial PNF technique, Massage therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Glioma, Glioblastoma Multiforme
Genetic Analysis of Brain Tumors
This study will analyze tissue and blood samples from patients with gliomas (a type of brain tumor) to develop a new classification system for these tumors.
- Conditions
- Glioma, Glioblastoma Multiforme, Anaplastic Astrocytoma, Oligodendroglioma
- Trial name
- NCT00031538
- Where
- 3 sites in United States
- Volunteers
- 674 people
- Sponsor
- National Cancer Institute (NCI)
Carpal Tunnel Syndrome
Assessment of Subsynovial Connective Tissue Thickness in Carpal Tunnel Syndrome
The general aim of this research is to gain insight in the role of SSCT in the etiology and progression of CTS. We hypothesize that (degenerative) damage of the SSCT occurs early on in the pathogenesis of CTS.
- Trial name
- NCT04491058
- Testing
- SSCT thickness measurement
- Where
- Belgium
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Acute Neurological Injury, Acute Medical Conditions
Transcutaneous Auricular Vagus Enhanced Recovery in the NeuroICU
This study will demonstrate the impact of taVNS on reducing adverse events in NeuroICU patients, determine if taVNS reduces length of stay, and quantify the economic benefits of taVNS implementation in a broader neurocritical…
- Trial name
- TAVERN (NCT07219108)
- Testing
- Auricular Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Washington University School of Medicine
Pigmented Skin Lesion, Melanoma
fPAM for the in Vivo Depth Measurement of Pigmented Lesions and Melanoma Depth
The investigators propose the use of functional photoacoustic microscopy (fPAM) to evaluate both benign and malignant pigmented lesions for tumor depth.
- Trial name
- NCT02613325
- Testing
- Functional photoacoustic microscopy, Standard of care surgical excision, Single cell photoacoustic microscopy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Metastatic Melanoma
Study of Immune Responses in Patients With Metastatic Melanoma
In this study, anti-OX40 will be given to patients with melanoma to find out how the immune system responds to treatment with anti-OX40.
- Trial name
- NCT01416844
- Testing
- anti-OX40
- Where
- United States
- Sponsor
- Providence Health & Services
Metastatic Melanoma
TIL Therapy in Metastatic Melanoma and IL2 Dose Assessment
This is a two arm, open-labelled phase II randomised trial of Tumour Infiltrating Lymphocytes (TIL) in metastatic melanoma patients given with preconditioning chemotherapy and Interleukin-2 (IL2).
- Trial name
- METILDA (NCT01995344)
- Testing
- Cyclophosphamide, Fludarabine, Tumour Infiltrating Lymphocytes
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- The Christie NHS Foundation Trust
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