Clinical trials: Nerve Examination
Muscular Dystrophies, Muscle Myopathies
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
Background: Some nerve and muscle disorders that start early in life (before age 25), like some forms of muscular dystrophy, can run in families. However, the genetic causes of these disorders are not known.
- Conditions
- Muscular Dystrophies, Muscle Myopathies, Hereditary Spastic Paraplegias, Inherited Neuropathies
- Trial name
- NCT01568658
- Where
- United States
- Volunteers
- 2,586 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Osteoarthritis, Knee
Effect of Transcutaneous Electrostimulation (TENS) on Pain and Physical Function in Patients With Knee Osteoarthritis
The proposed study is a multi-center, randomized, double blind (patient and assessor), sham controlled clinical trial using a parallel 2 group design recruiting 220 patients of at least 18 years of age.
- Trial name
- ETRELKA (NCT01875042)
- Testing
- TENS
- Where
- Switzerland
- Volunteers
- 220 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Neurofibromatosis Type 1
Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1
A physical training program will improve quality of life, participation in physical activity, motor coordination, muscle strength, and bone and muscle strength in children with neurofibromatosis type 1.
- Trial name
- NCT01058330
- Testing
- Plyometric training program
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Shriners Hospitals for Children
Meningioma
Magnesium and Intraoperative Blood Loss in Meningioma Surgery
Meningioma is the most common central nervous system tumor and craniotomy with tumor removal was associated with moderate blood loss and blood transfusion.
- Trial name
- NCT03558516
- Testing
- Magnesium group, Normal saline group
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Gastrointestinal Neoplasms, Genitourinary Cancer
Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study
Immune checkpoint inhibitors (ICIs) (also called "immunotherapy") are an effective family of anti-cancer drugs, but they can cause serious side effects.
- Conditions
- Gastrointestinal Neoplasms, Genitourinary Cancer, Thoracic Cancer, Sarcoma
- Trial name
- NCT07389525
- Testing
- ICI Therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Indiana University
Pudendal Neuralgia
Impact of Adding TENS to Conventional Physical Therapy Exercise on Pain Relief Among Patients With Pudendal Neuralgia.
Fifty two male participants, 30-50 years old, suffering from chronic pudendal neuralgia were randomly assigned either into experimental group (26 patients) received TENS plus the traditional physical therapy program( including…
- Trial name
- TENS (NCT04455659)
- Testing
- Trans-cutaneous Electrical Nerve Stimulation, Conventional physical therapy exercise
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Neck Pain, Musculoskeletal Diseases
Effectiveness of Scapula Mobilization on Mechanosensitivity of Upper Limb Neural Test 1 in Mechanical Neck Pain
Between 45% and 70% of the general population suffers neck pain at some point in their lives, making it one of the most frequent reasons for taking sick leave.
- Trial name
- ULNT1 (NCT04168476)
- Testing
- Interscapular muscle release or scapular mobilization technique as described by Travell and Simons., Calcaneus abduction and adduction mobilization technique
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aitor Vaquero Garrido
Brain and Central Nervous System Tumors
MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma
RATIONALE: Diagnostic procedures, such as MRI, may help in learning how well radiation therapy and chemotherapy work in killing tumor cells and allow doctors to plan better treatment.
- Trial name
- NCT00756106
- Testing
- temozolomide, Imaging biomarker analysis, Photon Radiation Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Massachusetts General Hospital
Neurologic Disorder, Brain Injuries
Comparison of Power Wheelchair Driving Performance Under Immersive and Non-immersive Conditions With Drivers With Neurological Disorders
This study aims to assess the impact of the choice of visual feedback solution (immersive via CAVE and VR headset; non-immersive via screen only) on driving performance and quality of experience on a physical driving simulator…
- Conditions
- Neurologic Disorder, Brain Injuries, Neurodegeneration
- Trial name
- SIMADAPT2 (NCT04894981)
- Testing
- Immersive condition (CAVE), Immersive condition (HMD), Non Immersive condition (Screen alone)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Pôle Saint Hélier
Melanoma
Teaching Skin Self -Examination to Melanoma Patients and Their Skin Check Partners
The proposed study is a continuation of a research program (STU00017005: Interventions to teach melanoma patients skin self-examination) designed to increase early detection of melanomas before they metastasize.
- Trial name
- PSW (NCT02854657)
- Testing
- Skin Self- examination structured training
- Where
- United States
- Volunteers
- 682 people
- Sponsor
- Northwestern University
Cancer
OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer
RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900302
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Melanoma (Skin Cancer)
Sun Exposure and Activities After Skin Cancer: Optimization of mHealth Interventions
The purpose of this study is to evaluate 5 different smartphone administered sun protection interventions that aim to reduce unprotected sun exposure in melanoma survivors.
- Trial name
- SESAME (NCT07556380)
- Testing
- UV Real-Time Alerts, Track Your Sun Protection, Current Conditions
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University
Neuroinflammatory Response, Nerve Injury
Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity
The aim of this observational study is to answer the following questions in individuals with acute and chronic exposure to organophosphates. The main questions to be addressed are 1.
- Conditions
- Neuroinflammatory Response, Nerve Injury, Nerve Damage, Neurotoxicity
- Trial name
- NCT06021262
- Testing
- exposure to organophosphates
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Brain Tumor, Medulloblastoma
Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study
QARIN 1 is a study of [18F]DPA-714 Translocation Protein (TSPO) Positron Emission Tomography (PET) for longitudinal, quantitative assessment of brain neuroinflammation following whole brain radiation therapy.
- Trial name
- NCT05128903
- Testing
- [18F]DPA714
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- St. Jude Children's Research Hospital
Glioblastoma
Comparison of Different Methods to Test MGMT Status in Glioblastoma Patients
Treatment for newly diagnosed glioblastomas currently involves surgical resection followed by Temozolomide chemotherapy with concomitant radiotherapy, and then 6 cycles of Temozolomide in adjuvant.
- Trial name
- ECOM (NCT01345370)
- Testing
- Temozolomide, Radiation Therapy
- Where
- 10 sites in France
- Volunteers
- 300 people
- Sponsor
- Center Eugene Marquis
Spinal Cord Injuries
Technology Development for Physical Rehabilitation of Patients With Upper Extremity Motor Deficits (RePlay)
Injuries and disease processes that produce upper extremity deficits are devastating to patients and their families. One potential avenue to treat these neurological disorders is through the enhancement of neural plasticity…
- Trial name
- RePlay (NCT03621969)
- Testing
- Physical exam and medical history, Assessments, Patient Instruction and use of Device (RePlay)
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Mandibular Nerve
Assessment of the Anterior Loop of the IAN in a Sample of Egyptian Population Using CBCT
in this study the prevalence \& length of the anterior loop of the inferior alveolar nerve will be calculated and measured on retrospective CBCT patient's scans
- Trial name
- NCT04465617
- Where
- Egypt
- Volunteers
- 192 people
- Sponsor
- Cairo University
CTS
Pre-operative Sonographic Assessment of The Median Nerve in Carpal Tunnel Syndrome. Does it Affect The Operative Procedure?
Sonographic Assessment of The Median Nerve in Carpal Tunnel Syndrome to assess the surgical importance and added value of superficial ultrasonography in assessment of the median nerve in CTS.
- Trial name
- NCT03082027
- Testing
- ultrasonography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Skin Cancer
A Pilot Study to Evaluate Optical Spectroscopy of Pigmented Skin Lesions
The incidence of malignant melanoma has increased dramatically in recent decades. In 1930, the lifetime risk of an individual in the United States developing melanoma was 1 in 1,500.
- Trial name
- NCT00633516
- Testing
- Optical Spectroscopy
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Multiple System Atrophy, Parkinson Disease
Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders.
- Conditions
- Multiple System Atrophy, Parkinson Disease, Progressive Supranuclear Palsy, Motor Neuron Disease
- Trial name
- FEEMSA (NCT04706234)
- Where
- 16 sites in Austria, Germany and 6 more
- Volunteers
- 350 people
- Sponsor
- Kliniken Beelitz GmbH