Clinical trials: Nerve Injury
Carpal Tunnel Syndrome
Gabapentin and Neural Mobilization Pain Reduction Effect Compared to Only Gabapentine
In the present investigation the pain reduction effects of a physiotherapy technique combined with pharmaceutical gabapentin treatment will be compared to those produced by gabapentin (only) treatment, in subjects who suffer the…
- Trial name
- NCT06778798
- Testing
- Median nerve neural mobilization and oral gabapentin, Gabapentin 300mg
- Where
- Venezuela
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Primary Aldosteronism, Adrenal Tumor
Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
The main goal of this study is to follow patients with functional adrenal tumors during the time before and after their surgery.
- Conditions
- Primary Aldosteronism, Adrenal Tumor, Cushing s Syndrome, Pheochromocytoma/Paraganglioma (PPGL)
- Trial name
- NCT07182175
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University First Hospital
Carpal Tunnel Syndrome (CTS), Wrist
Analysis of Radiographic Indices in Carpal Tunnel Syndrome
The aim of this study was to compare wrist radiographic indices in patients with idiopathic carpal tunnel syndrome (CTS) with normal cases.
- Conditions
- Carpal Tunnel Syndrome (CTS), Wrist, X-Ray, Radiography
- Trial name
- NCT06841809
- Where
- Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Ankara Training and Research Hospital
Pain, Postoperative, Anterior Cruciate Ligament Injuries
IPACK on Early Pain Scores After ACL Reconstruction
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery.
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Trial name
- NCT05985629
- Testing
- IPACK
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Loyola University
Complex Regional Pain Syndrome, Carpal Tunnel Syndrome
Examination of the Pathophysiologic Mechanisms of CRPS by Using QST, CPM, RIC, and Heart Rate Variability QST
This study aims for a better understanding of the pathophysiological mechanisms of the complex regional pain syndrome (CRPS). This will be done by testing the quantitative sensory testing, the remote ischemic conditioning, the…
- Conditions
- Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, Neuralgia
- Trial name
- NCT02261012
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Cubital Tunnel Syndrome
Presence of the Arcade of Struthers on Preoperative Ultrasound
To determine the correlation between the presence of the arcade of Struthers on preoperative ultrasound and during endoscopic surgery for cubital tunnel syndrome, and to determine the reliability of a portable ultrasound probe to…
- Trial name
- NCT04658511
- Testing
- Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Median Nerve Entrapment, Carpal Tunnel Syndrome
Effect of Neurodynamic Mobilization on Median Nerve Conduction Velocity in Carpal Tunnel Syndrome
The purpose of this study is to examine: 1. The effect of neurodynamic mobilization on the sensory and motor median nerve conduction velocity in carpal tunnel syndrome. 2.
- Trial name
- NCT05788471
- Testing
- conventional Treatment, Neurodynamic mobilization
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Optic Nerve Sheath, Hypertonic Saline
Point of Care Optic Nerve Sheath Ultrasound to Assess Intracranial Pressure
Elevated intracranial pressure (ICP) is one of the most common symptoms encountered in a variety of traumatic injuries and diseases.
- Trial name
- NCT04686344
- Testing
- intermittent boluses of Hypertonic saline, continuous infusion of Hypertonic saline
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Brachial Plexus Injury, Peripheral Nerve Injuries
Somatosensory Evoked Potential (SSEP) Monitoring for Brachial Plexus Injury
Brachial plexus block is a common regional anesthesia technique which is performed by anesthesiologists to anesthetize the arm for surgery.
- Trial name
- NCT03409536
- Testing
- SSEP monitoring
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Carpal Tunnel Syndrome, Pain, Chronic
Median Nerve Hydro-dissection Using Single Injection of Hyalase as a Novel Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline of the median nerve could offer symptoms and clinical improvement
- Trial name
- NCT03177915
- Testing
- Hylase, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Peripheral Nerve Injury Digital Nerve Hand Left
Optimization of Peripheral Nerve Reconstruction: A Non-inferiority Trial
1. To analyse the outcome of different treatment options of peripheral nerve repair with no gap (group 1) and with a critical sized (>5mm) defect (group 2) in order to optimize peripheral nerve repair 2.
- Trial name
- NCT01573650
- Where
- Switzerland
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Digital Nerve Injury
Vitamin D3 in Sensory Recovery After Digital NERVe Suture (D3NERV).
Digital nerve injuries are frequent in a FESUM center (Federation Européenne des Services d'Urgences Mains), and they need to be repaired in order to reduce the risk of hypoesthesia and to prevent painful neuroma.
- Trial name
- D3NERV (NCT04115982)
- Testing
- Cholecalciferol
- Where
- 3 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Intracranial Hemorrhages, Brain Injuries
Comparison of Pupilometer and Ultrasound of Optic Nerve Sheath Diameter in Estimating Intracranial Pressure (ICP)
The purpose of this investigator-initiated study is to compare the use of pupilometer and ultrasound assessment of optic nerve sheath diameter in predicting the ICP and to see if there is a value that could be used to indicate…
- Conditions
- Intracranial Hemorrhages, Brain Injuries, Subarachnoid Hemorrhage, Ischemic Stroke
- Trial name
- CUSPICP (NCT03115450)
- Testing
- Ultrasound, Pupilometer
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Loma Linda University
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or recommended dose for expansion (RDE) of intratumoral…
- Conditions
- Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Lymphoma, Non-Hodgkin
- Trial name
- ON-5001 (NCT06022029)
- Testing
- ONM-501, Cemiplimab
- Where
- 16 sites in United States, Australia
- Volunteers
- 168 people
- Sponsor
- OncoNano Medicine, Inc.
Hip Fractures, Pain, Acute
Ultrasound Guided Nerve Block for Hip Fracture Pain Management at Emergency Department
The main objective is to determine if ultrasound guided suprainguinal iliac fascia block leads in better clinical outcomes such as pain management or time to home discharge.
- Conditions
- Hip Fractures, Pain, Acute, Ultrasound Therapy; Complications
- Trial name
- NCT05403073
- Testing
- Ultrasound guided Suprainguinal Iliac Fascia Nerve Block.
- Volunteers
- 72 people
- Sponsor
- Hospital San Carlos, Madrid
Clavicle Fracture
Supraclavicular Nerve During Clavicle ORIF
Clavicle fractures are a common orthopedic injury and make up 2.6%-5% of all fractures. Despite the benefits of operative management, post-operative chest wall paresthesia is a well-known complication among surgeons and is well…
- Trial name
- NCT06050473
- Testing
- Nerve-sacrificing procedure, Nerve preserving procedure
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Carpal Tunnel Syndrome
Hydrodissection in Carpal Tunnel Syndrome
Compare the efficacy on carpal tunnel syndrome (CTS) treatment between hydrodissection with hyaluronic acid (HA) vs 5% dextrose
- Trial name
- NCT06188390
- Testing
- Ultrasound guided median nerve hydrodissection injection with Hyaluronic acid, Ultrasound guided median nerve hydrodissection injection with Dextrose water
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Carpal Tunnel Syndrome (CTS), Mobility
Additional Effects of Shockwave Therapy Along With Median Nerve Gliding Exercises in Patient With Carpal Tunnel Syndrome.
Carpal Tunnel Syndrome (CTS) is a widespread condition resulting from the compression of the median nerve, causing significant pain, numbness, and weakness in the hand.This study decisively evaluates the impactful effects of…
- Conditions
- Carpal Tunnel Syndrome (CTS), Mobility, Hand Functions
- Trial name
- NCT07317024
- Testing
- NERVE GLIDING EXERCISES, SHOCKWAVE THERAPY
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Foundation University Islamabad
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Nerve Injury
Effects of 3D Printing Writing Assisitive Device on Feasibility in Patients With Nerve Injury
Injury to the central or peripheral nerves can lead to limited hand function and further affect the ability of writing. The use of assistive devices can assist writing performance.
- Trial name
- NCT05589324
- Testing
- 3D-printed writing aids task
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital