Clinical trials: Nerve Injury, open to volunteers
Carpal Tunnel Syndrome (CTS)
Pulsed Radiofrequency Versus Hyaluronidase Hydrodissection for Treatment of Carpal Tunnel Syndrome
The aim of this study is to compare the clinical efficacy and safety of ultrasound-guided pulsed radiofrequency and hyaluronidase hydrodissection in the treatment of carpal tunnel syndrome.
- Trial name
- NCT07269613
- Testing
- Pulsed Radiofrequency, Hyaluronidase Hydrodissection
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Sohag University
Ischemic Heart Disease, Nerve Injury
Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study
Evaluation of potential nerve damage after radial CAG/PCI.
- Conditions
- Ischemic Heart Disease, Nerve Injury, Carpal Tunnel Syndrome
- Trial name
- ACCESS-IV (NCT05365282)
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aarhus University Hospital Skejby
Burn Injury
Non-Invasive Vagus Nerve Stimulation in Burn Patients During Dressing
This study will evaluate the effects of non-invasive vagus nerve stimulation on pain, anxiety, and quality of life in burn patients during the dressing process. Participants will be randomly assigned to one of three groups.
- Trial name
- NCT07566910
- Testing
- Non-Invasive Vagus Nerve Stimulation, Standard Dressing Care
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Fenerbahce University
Carpal Tunnel Syndrome
Thenar Muscle Ultrasound in CTS Evaluation
This study will include 20 patients aged 18-75 years who have been diagnosed with carpal tunnel syndrome (CTS) based on electrophysiological examinations performed within the last three months, as well as 20 healthy volunteers…
- Trial name
- NCT06730724
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Beylikduzu State Hospital
Carpal Tunnel Syndrome (CTS)
Comparison of Rest Splints vs High-Intensity Laser Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the effectiveness of rest splints and high-intensity laser therapy(HILT) added to physical therapy programs for patients with carpal tunnel syndrome in terms of pain, function, nerve conduction…
- Trial name
- NCT07294157
- Testing
- Rest splint group, high-intensity laser therapy (HILT)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Afyonkarahisar Health Sciences University
Carpal Tunnel Syndrome, Median Neuropathy
Hydrodissection With Neuroprolotherapy Versus Open Release for Carpal Tunnel Syndrome
This study is a randomized controlled, parallel-group, non-inferiority trial designed to compare ultrasound-guided hydrodissection combined with neuroprolotherapy versus open carpal tunnel release in patients with carpal tunnel…
- Trial name
- HN-CTS (NCT07576803)
- Testing
- Ultrasound-guided Hydrodissection of the Median Nerve, Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Carpal Tunnel Syndrome, Wound Infection
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Carpal Tunnel Syndrome is a prevalent condition, up to 9% in women and 0.6% in men. Surgical decompression in the most effective treatment. After surgery, approximately 1,8% of the patients develop a wound infection.
- Conditions
- Carpal Tunnel Syndrome, Wound Infection, Suture, Complication
- Trial name
- SENSE (NCT05431101)
- Testing
- Carpal Tunnel Release
- Where
- 2 sites in Netherlands
- Volunteers
- 2,604 people, healthy volunteers welcome
- Sponsor
- Gelre Hospitals
Chronic Pain, PTSD - Post Traumatic Stress Disorder
Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans
Veterans in Canada are twice as likely as the general population to experience chronic pain. This pain is often linked to post-traumatic stress disorder (PTSD), and both have a major impact on their quality of life.
- Conditions
- Chronic Pain, PTSD - Post Traumatic Stress Disorder, Quality of Life (QOL)
- Trial name
- VR & CN-NINM (NCT07137845)
- Testing
- Virtual reality, Cranial nerve non-invasive neuromodulation (CN-NINM)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Radiation Necrosis, High Grade Glioma (III or IV)
Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases
Cerebral radiation necrosis (CRN) is a severe complication of high-dose radiation for brain metastases (BM) or glioma, which can potentially cause significant neurologic symptoms leading to serious morbidity and impaired quality…
- Conditions
- Radiation Necrosis, High Grade Glioma (III or IV), Brain Metastasases, Radiation Toxicity
- Trial name
- BRAINS (NCT06888817)
- Testing
- Bevacizumab, Dexamethasone
- Where
- 6 sites in Netherlands
- Volunteers
- 408 people
- Sponsor
- The Netherlands Cancer Institute
mTBI - Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Mindful RAVANS Study
This pilot study is testing a new treatment for people who still have frequent headaches months after a mild traumatic brain injury, with about half of the participants coming from military or veteran backgrounds.
- Conditions
- mTBI - Mild Traumatic Brain Injury, Posttraumatic Stress Disorder, Posttraumatic Headache
- Trial name
- RAVANS (NCT07872761)
- Testing
- Cala-RAVANS (Model CR-2)
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Retinal Disease, Age-Related Macular Degeneration
Stem Cell Ophthalmology Treatment Study II
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
- Conditions
- Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease
- Trial name
- SCOTS2 (NCT03011541)
- Testing
- Arm 1
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Post-Concussion Syndrome, COVID Long-Haul
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Stimulation (a Neurostim device) on children with pain and Post Concussion symptoms.
- Conditions
- Post-Concussion Syndrome, COVID Long-Haul, COVID-19
- Trial name
- NCT04978571
- Testing
- percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Children's Hospital of Orange County
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Carpal Tunnel Syndrome (CTS), Nerve Conduction
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound Versus Nerve Conduction Studies (NCS)
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound vs. Nerve Conduction Study (NCS) This clinical study aims to determine whether ultrasound can be as practical as NCS in…
- Conditions
- Carpal Tunnel Syndrome (CTS), Nerve Conduction, Ultrasound
- Trial name
- NCT06926777
- Testing
- Nerve Conduction Study
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Combined Military Hospital Kohat Pakistan
Vestibular Schwannoma, Ototoxicity
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma
The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated…
- Trial name
- NCT05641441
- Testing
- Stereotactic radiosurgery
- Where
- Switzerland
- Volunteers
- 258 people
- Sponsor
- University Hospital, Geneva
Carpal Tunnel Syndrome (CTS) in Breast Cancer Patients
Laser Acupuncture on Carpal Tunnel Syndrome .
The study will be carried out on a total number of fifty-four females with age ranged 40 - 60 years old suffering from CTS post mastectomy ,the patients will be randomly assigned into two groups equal in number (27 patients for…
- Trial name
- NCT07405008
- Testing
- LASER acupuncture technique, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Alzheimer Disease, Old Age; Dementia
Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)
The BAD-GER study is a multicenter, prospective, three-arm observational study serving to validate a prognostic biomarker algorithm for mortality and hospital readmission; this algorithm will be developed through the…
- Trial name
- BAD-GER (NCT07435467)
- Testing
- collection of blood samples
- Where
- 3 sites in Italy
- Volunteers
- 400 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Carpal Tunnel Syndrome (CTS)
Evaluation of Dynavisc in Pain Reduction Following Revision Surgery for Persistent or Recurrent Carpal Tunnel Syndrome
The trial will evaluate the efficacy of DYNAVISC in subjects with a diagnosis of persistent or recurrent carpal tunnel syndrome. This is a prospective, multicenter, randomized, evaluator-blinded clinical trial.
- Trial name
- NCT06593977
- Testing
- Dynavisc
- Where
- 4 sites in Belgium, Brazil and 1 more
- Volunteers
- 50 people
- Sponsor
- FzioMed
Optic Nerve Injuries, Sellar Tumor
Optic Nerve Stimulation To Prevent Visual Deficits After Endoscopic Cranial Approaches
Assessing the function of the optic nerve is paramount during various neurosurgical procedures. Effective optic nerve monitoring has remained elusive as Visual Evoked Potentials (the current existing tool) provides only diffuse…
- Conditions
- Optic Nerve Injuries, Sellar Tumor, Skull Base Neoplasms
- Trial name
- NCT06495580
- Testing
- Optic Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco