Clinical trials: Nervous System Complication
Urinary Incontinence
A Comparison of Tolterodine and Placebo Treatments on Nocturnal Frequency and Sleep Quality in Women After Menopause.
This study is being done to compare frequency of urination during the night when women take tolterodine tablets vs. when they take placebo tablets.
- Trial name
- NCT00323635
- Testing
- tolterodine
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pain, Postoperative
Erector Spinae Plane Block for Post-thoracotomy Pain
Post-thoracotomy pain is one of the most severe forms of post-operative pain. Among the most common techniques for the management of post-thoracotomy pain, there are the intercostal nerve block, and a recently described block…
- Trial name
- NCT04013815
- Testing
- erector spinae plane block with ropivacaine, Intercostal nerve block with ropivacaine
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Hyperalgesia
Opioid-induced Hyperalgesia After Remifentanil Infusion
Remifentanil is a rapid-acting opioid which has been widely used in pain treatment during surgery for the last 15 years 1. Remifentanil is rapidly eliminated (minutes) from the body after end of infusion, and this makes it easily…
- Trial name
- NCT01702389
- Testing
- Remifentanil
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Assessment, Self, Muscle Atrophy
Correlation of Muscle Ultrasound Measures (2D and 3D) With Biphotonic X-ray Absorptiometry in Oldest Old Patients.
The sarcopenia diagnosis is based on the muscle mass and on impaired physical performance. The emerging field of ultrasound assessment of muscle mass in older patients is based on 2d parameters with prediction equations for…
- Conditions
- Assessment, Self, Muscle Atrophy, Ultrasound Therapy; Complications, Aging
- Trial name
- DIASEM (NCT04753450)
- Testing
- No intervention
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Postoperative Delirium, Postoperative Cognitive Dysfunction
Modulating ApoE Signalling to Reduce Brain Inflammation, deLirium and postopErative Cognitive Dysfunction
This research study will evaluate the effectiveness and estimate the feasibility of administering an investigational drug called 'CN-105' (the study drug), to prevent postoperative cognitive decline, delirium (serious confusion)…
- Trial name
- MARBLE (NCT03802396)
- Testing
- CN-105
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Miles Berger, MD PhD
Cerebral Palsy, Prematurity
Study of Generalized Movements for Early Prediction of Cerebral Palsy
The purpose of this study is to assess the predictive value of generalized movements in preterm and term infants who are at risk for development of cerebral palsy.
- Trial name
- NCT00749008
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Charles R. Neal,
Neurogenic Bladder
Comparison of Mobile Education and Face-to-Face Intermittent Catheterization Education
Today, Clean Intermittent Catheterization (CIC) is widely used to drain urine accumulated in the bladder in acute or chronic problems such as neurogenic bladder and prostate hypertrophy.The success of the technique depends…
- Trial name
- NCT06917027
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Mothers, Postpartum Depression
Early Half Swaddling and Kangaroo Care Practices on Maternal Sleep Quality and Postpartum Depression in Term Babies
Aim: In this prospective, randomized controlled study, it was aimed to examine the effects of early half-swaddle and kangaroo care practices in term babies on maternal sleep quality and postpartum depression.
- Trial name
- NCT06348316
- Testing
- Half swaddle, Kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Trakya University
Depression, Postpartum, Pregnancy
Labor Pain and Postpartum Behavioral Health Outcomes Study
In this pilot prospective longitudinal observational study, women who are pregnant and who will be experiencing childbirth for the first time will be recruited at the third trimester and observed longitudinally for psychiatric…
- Conditions
- Depression, Postpartum, Pregnancy, Child Development, Pain
- Trial name
- LPPD (NCT02692404)
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Preeclampsia, Intracranial Pressure Increase
Assessment of Optic Nerve Sheath Diameter in Preeclamptic Pregnant Women Using Ultrasonography and Anesthetic Management
Preeclampsia is a serious condition associated with complications such as pulmonary edema, placental abruption, hemolysis, thrombocytopenia, and cardiac, renal, and neurological complications, occurring at a rate of 2.7-8% in…
- Conditions
- Preeclampsia, Intracranial Pressure Increase, Pregnancy; Anesthesia, Adverse Effect, Central Nervous System
- Trial name
- NCT06522295
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Emergence Agitation, Nasal Surgery
Emergence Agitation
The impact of sugammadex on agitation upon emergence following adult nasal surgeries is an issue which needs to be studied that links anesthetic management with postoperative recovery.
- Trial name
- Sugamadex (NCT07253428)
- Testing
- Neostigmine + Atropine, Sugamadex
- Where
- Saudi Arabia
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autoimmune Diseases, Cardiovascular Disorders
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic conditions.
- Conditions
- Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
- Trial name
- NCT04684602
- Testing
- PrimePro™/ PrimeMSK™
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Thomas Advanced Medical LLC
Kidney Diseases, Brain Diseases
Medical Images Collection Research
This is a not-for-profit project for the collection, archiving and reuse of magnetic resonance imaging, computed tomography and ultrasound images, and related demographic and clinical data, for research purposes only.
- Trial name
- MEDICALBUM (NCT06354829)
- Testing
- Medical imaging procedures
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Type 2 Diabetes, Osteoporosis
Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes
The DIACTIVE study is a randomized controlled trial with a 5- year follow-up designed to evaluate the impact of comprehensive screening and multicomponent interventions on fall prevention, bone health, nerve function and…
- Conditions
- Type 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall Prevention
- Trial name
- DiaACTIVE (NCT06745544)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Apnea, Obstructive Sleep, Pregnancy Complications
Sleep Apnea Syndrome in Obese Women During Pregnancy
Excess weight or obesity is associated with an increased risk of health disorders: high blood pressure, diabetes, cardiovascular risks, dyslipidemia and sleep apneas.
- Conditions
- Apnea, Obstructive Sleep, Pregnancy Complications, Pre-Eclampsia, Obesity
- Trial name
- NCT03509805
- Testing
- polysomnography
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Anxiety, Cesarean Section Complications
The Effect of Pre-operative Videotape Before a Planned Cesarean Section on Anxiety Level
The study aim is to examine the relationship between providing information to women prior to elective cesarean delivery and anxiety levels around surgery. the patients will be assigned into two groups - intervention and control.
- Conditions
- Anxiety, Cesarean Section Complications, Pain, Postoperative, Analgesia
- Trial name
- NCT04177966
- Testing
- pre-prepared video describing the cesarean surgery, general information
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Posterior Fossa Hemorrhage, Lung Cancer
Pilot Study of Model Based Iterative Reconstruction Using 64-Slice
This study is being performed to confirm that the new technique, Model-Based Iterative Reconstruction (MBIR) with reduced radiation dose can deliver equivalent image quality for CT scans compared to current techniques (Filtered…
- Conditions
- Posterior Fossa Hemorrhage, Lung Cancer, Flank Pain, Urolithiasis
- Trial name
- MBIR (NCT01431378)
- Where
- 3 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Emergence Agitation, Anesthetics
The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty
Emergence agitation, defined as restlessness, disorientation, arousal, and/or inconsolable crying, is a common phenomenon seen in the early phase of recovery from general anesthesia; this may cause respiratory depression, nausea…
- Conditions
- Emergence Agitation, Anesthetics, Rhinoplasty
- Trial name
- NCT05601674
- Testing
- : Conventional flow Anesthesia, Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Inonu University