Clinical trials: Nervous System Disorders
Epilepsy, Epilepsy, Temporal Lobe
Brain Network Activation Analysis in Epilepsy
This is a prospective study investigating the utility of Brain Network Activation (BNA) analysis in patients with epilepsy.
- Trial name
- NCT03265925
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Stroke, Aphasia
Links Between Motor Abilities and Language Ability Deficits in Patients With Post-stroke Aphasia
Aphasia is a language disorder that affects oral and written expression and/or comprehension. It's one of the most disabling consequence of stroke.
- Trial name
- MOTOLANG-AVC (NCT05776368)
- Testing
- Syntactic comprehension battery (BCS), Montreal Cognitive Assessment (MOCA), Purdue Pegboard Test
- Where
- 3 sites in France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Breathing-Related Sleep Disorder, Sleep Disorder (Disorder)
Wearable Technology in the Detection and Evaluation of Sleep-Related Breathing Disorders
This project is an observational study that aims to evaluate the accuracy of wearable devices in detecting potential sleep-related breathing disorders (SRBD) in individuals visiting the Sleep-Related Breathing Disorders and Home…
- Trial name
- ReSTech (NCT06606691)
- Testing
- Xiaomi Mi Smart Band 8
- Where
- 2 sites in Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Diphtheria, Tetanus
To Evaluate the Immunogenicity and Safety of DTaP-IPV Vaccine Administered as a Boosting Dose to Healthy Children of 4-6 Years
The study objective is to assess the immunogenicity and safety of DTaP-IPV combination vaccine administered as a boosting dose to healthy 4 to 6-year-old children who received three doses of primary immunization against…
- Conditions
- Diphtheria, Tetanus, Pertussis, Poliomyelitis
- Trial name
- Aladdin (NCT04618640)
- Testing
- DTaP-IPV combination vaccine
- Where
- 26 sites in South Korea
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Boryung Biopharma Co., Ltd.
Mandible Fracture
Stability of Angle Fracture Fixation With (K) Shaped Titanium Miniplates Versus Two Miniplates
In patients with angle fracture , will the (K) shaped titanium miniplates provide more stable fixation than two conventional miniplates? Many studies have been conducted to compare between different techniques of fixation used in…
- Trial name
- NCT03839368
- Testing
- fixation of angle fracture
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amyotrophic Lateral Sclerosis
mGluR5 Imaging in ALS Using PET
In ALS models, it was shown that receptors, that bind an important messenger substance (glutamate) in the brain, are increased. In this research project, the investigators want to use a specific radioactive substance to find out…
- Trial name
- NCT05340660
- Testing
- [ 18 F]PSS232
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nathalie Braun
Ischemic Heart Disease, Transient Ischemic Attack
TomVasc - Vascular Effects of Tomato Extract
Does tomato extract improve blood vessel function in healthy people and people with cardiovascular disease? Atherosclerosis ('furring' of the arteries) affects the functioning of blood vessels, narrowing and eventually blocking…
- Conditions
- Ischemic Heart Disease, Transient Ischemic Attack, Stroke, Peripheral Vascular Disease
- Trial name
- TomVasc (NCT01100385)
- Testing
- Ateronon
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Multiple Sclerosis
Detection of Pattern of Some Unusual Signs and Symptoms of Multiple Sclerosis
Each Multiple Sclerosis patient will be submitted to Cognitive Abilities Screening Instrument (CASI), Expanded Disability Status Scale, Epowrth Sleeping Scale(ESS),Fatigue Severity Scale(FSS), Hamilton Depression Rating Scale…
- Trial name
- NCT04100343
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obstructive Sleep Apnea
Exercise Intolerance in Obstructive Sleep Apnea Syndrome Patients
The syndrome of obstructive sleep apnea (OSAS) is a public health problem that affects 2 to 4% of the general population. The patients with OSAS frequently complain of intolerance to exercise muscle fatigue and a significant even…
- Trial name
- EXAOS (NCT00837018)
- Testing
- physical exercise program
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Alzheimer Disease, Early Onset, Protein; Disease
Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease
This study intends to adopt standardized and rigorous cross-sectional research, collect biological specimens (including blood, feces, urine, saliva and tongue coating) from eligible subjects, and use liquid chromatography/mass…
- Trial name
- NCT04804618
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Ehler's Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Children and Adolescents With Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- NCT02712060
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Skin Burns
The Counter-irritating Efficacy of Topical Povidone-iodine in Thermal Burns
Skin burns are one of the causes of disability, suffering and death in humans. Anecdotal, uncontrolled studies have shown the efficacy of povidone-iodine ointment in human skin burns, provided the preparation was applied shortly…
- Trial name
- NCT01350713
- Testing
- povidone iodine
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Muscle Function, Handgrip Strength Test
Muscle Assessment in Women Who Have Undergone Roux-en-Y Gastric Bypass Surgery
The purpose of this study is to assess muscle function in women at least two years after being submitted to Roux-en-Y Gastric Bypass Surgery and compare with a control group
- Trial name
- FUBA (NCT02811393)
- Testing
- Assess muscle function
- Where
- Chile
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Chile
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Mild Cognitive Impairment (MCI), Alzheimer's Disease (AD)
Alzheimer's Disease Neuroimaging Initiative 3
Since its launch in 2004, the overarching aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) has been realized in informing the design of therapeutic trials in AD.
- Trial name
- ADNI3 (NCT02854033)
- Where
- 59 sites in United States, Canada
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Diabetes Mellitus, Type 1, Behavior, Health
Game-based Pediatric Diabetes Education
The goal of this study is to evaluate the impact of a mobile app video game called Digital Vaccine for Type 1 Diabetes (DVx-T1D)™, proposed as a low-risk, non-invasive, digital therapeutic candidate for behavior change in…
- Trial name
- DVx-T1D (NCT06264258)
- Testing
- DVx-T1D™ app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Parkinson Disease, Healthy Volunteer
Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
The research study is being conducted to test how a specialized type of Positron Emission Tomography (PET/CT) scan could potentially be useful in diagnosing or monitoring treatment in people with Parkinson's disease.
- Trial name
- NCT04062526
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Essential Tremor, Parkinson Disease
Environmental Epidemiology of Essential Tremor
This study's research is devoted to studying the causes of tremor, and especially essential tremor (ET), which is the most common type of tremor.
- Trial name
- RULET (NCT04576676)
- Where
- United States
- Volunteers
- 1,497 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Parkinson Disease, Healthy Aging
Longitudinal Analysis of Gait Variability to Predict Falls in Parkinson's Disease
The broad goal of this research project is to improve the prediction of falls in patients with Parkinson's disease (PD) through a comprehensive multidisciplinary approach that includes longitudinal measurements of walking…
- Trial name
- NCT04339543
- Testing
- Cognitive dual-task walking
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hemophilia A, Hemophilia B
Gaining Insight Into the Complexity of Pain in Patients With Haemophilia
Joint pain has been reported as a major problem in people with haemophilia (PwH). Therefore, haemophilia in adults seems clinically more related to a musculoskeletal disorder than a bleeding disorder, with many patients reporting…
- Trial name
- NCT05606640
- Testing
- Biopsychological pain assessment
- Where
- 2 sites in Belgium
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
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