Clinical trials: Nervous System Disorders
Cognitive Impairment, Mild, Dementia
Effects of Training Dose on Computerized Cognitive Training in Patients With Cognitive Impairment
The goal of this observational study is to explore the optimal dose of computerized cognitive training in patients with cognitive impairment.
- Trial name
- NCT05922319
- Testing
- Computerized cognitive training with different training doses
- Where
- China
- Volunteers
- 21,845 people
- Sponsor
- Xuanwu Hospital, Beijing
Chronic Pain, Ptsd
Improving Dysregulated Neural Networks With EEG-neurofeedback
Comorbid PTSD in the context of chronic pain rehabilitation is a major problem. The lack of effective and efficient methods that can be integrated into current practice is needed.
- Trial name
- NCT06587919
- Testing
- Neurofeedback
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Southern Denmark
Carpal Tunnel
Clinical Outcomes of USCTR vs. mOCTR
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy and affects 3-6% of adults in the United States.
- Trial name
- NCT04504019
- Testing
- USCTR, mOCTR
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
MS (Multiple Sclerosis), Sexual Dysfunctions
Ex-Plissit Model Based Counseling on Sexual Function and Sexual Satisfaction
Aimed to determine the effect of sexual education based on the EX-PLISSIT model on sexual function and sexual satisfaction in women with multiple sclerosis. The present study was a pretest-posttest randomized controlled study.
- Conditions
- MS (Multiple Sclerosis), Sexual Dysfunctions, Counseling
- Trial name
- NCT06199219
- Testing
- Sexual counseling, based on the extended (EX-PLISSIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Necmettin Erbakan University
Primary Sjögren Syndrome, Sarcopenia
Possible Sarcopenia, Sarcopenia, and Functional Status in Patients With Primary Sjögren's Syndrome
The aim of this study is to evaluate the frequency of probable sarcopenia and sarcopenia in patients with primary Sjögren syndrome and to investigate the effects of sarcopenia on functional status, muscle strength, and quality of…
- Trial name
- NCT07804719
- Testing
- dexa, hand grip strength, myostatin, follistatin
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Cirrhosis, Aerobic Exercises
The Efficacy of Aerobic Exercise Training on ANS and Endothelial Function in Compensated Cirrhosis
The goal of this randomized controlled trial is to investigate whether a 16-week structured aerobic exercise program combined with nutritional consultation can improve autonomic and endothelial function in patients with…
- Conditions
- Cirrhosis, Aerobic Exercises, Lifestyle Modification, Endothelial Function
- Trial name
- NCT06288828
- Testing
- Aerobic exercise + Nutrition consultant, Nutrition consultant
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Colposcopy
Lidocaine Spray vs Coughing for Pain Relief During Colposcopy
Cervical cancer is the third most common genital cancer worldwide. The diagnosis of cervical cancer is performed with the cervical biopsy which is guided by the colposcopy.
- Trial name
- NCT03100565
- Testing
- local lidocaine spray, forced coughing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Yuzuncu Yil University
Neuroblastoma, Medulloblastoma
Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer
The purpose of this study is to test the feasibility (ability to be done) of experimental technologies to determine a tumor's molecular makeup (gene expression profile) and mutations.
- Conditions
- Neuroblastoma, Medulloblastoma, Brain Tumors, Rare Tumors
- Trial name
- NCT01802567
- Testing
- Guided Therapy- Pediatric Gene Analysis Platform
- Where
- 13 sites in United States
- Volunteers
- 52 people
- Sponsor
- Giselle Sholler
Stroke, Inpatients
A Novel Approach to Enhance True Recovery After Stroke
The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies.
- Conditions
- Stroke, Inpatients, Recovery of Function, Observational Study
- Trial name
- NCT05359367
- Testing
- Observational
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Danderyd Hospital
Alzheimer's Disease
Study Evaluating Safety, Tolerability, Pharmacokinetics and 5 HT1A Receptor Occupancy
The study will include a preliminary pharmacokinetics (PK) / safety / tolerability evaluation in healthy elderly subjects followed by the Receptor Occupancy (RO) evaluations in healthy elderly subjects and in Alzheimer's Disease…
- Trial name
- NCT00499200
- Testing
- SRA-444
- Where
- Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Diabetes, Dementia
Enhanced Quality in Primary Care for Elders With Diabetes and Dementia
The purpose of this study is to develop and test a care quality improvement intervention featuring use of consensus decisional guidance for the medical management of diabetes (DM) in patients with Alzheimer's disease and related…
- Conditions
- Diabetes, Dementia, Alzheimer Disease
- Trial name
- EQUIPED-ADRD (NCT03723707)
- Testing
- EQUIPED-ADRD Intervention, Control (CON)
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- NYU Langone Health
Multiple Sclerosis (MS) Relapsing Remitting
A Multicenter Clinical Trial Evaluating the Efficacy and Safety of Taurine as an Adjunctive Therapy in Multiple Sclerosis
This multicenter, randomized, open-label clinical trial aims to evaluate the efficacy and safety of taurine as an adjunctive therapy to standard disease-modifying treatments (DMTs) in patients with multiple sclerosis (MS).
- Trial name
- NCT07263607
- Testing
- DMTs + taurine, DMTs
- Volunteers
- 80 people
- Sponsor
- Sichuan Academy of Medical Sciences
Vestibular Schwannoma
Response Prediction After GKS in Patients With Vestibular Schwannoma Using DCE MR Imaging
Response Prediction after Gamma Knife Surgery (GKS) in Patients with Vestibular Schwannoma using Dynamic Contrast-Enhanced (DCE) MR Imaging
- Trial name
- NCT03097822
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Phrenic Nerve Paralysis
Supraclavicular Block vs Retroclavicular Block: Incidence of Phrenic Nerve Paralysis
The aim of this study is to evaluate differences between ultrasound guided supraclavicular versus retroclavicular brachial plexus blocks: two similar brachial plexus nerve block techniques that differ in their needle trajectory…
- Trial name
- NCT02631122
- Testing
- Supraclavicular vs Retroclavicular Nerve Block
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea Syndromes
Study of Anatomo-functional Correlation of the Upper Airways
Sleep apnea-hypopnea syndrome (SAHS) is a disorder of nocturnal ventilation due to the occurrence abnormally frequent pauses in breathing.
- Trial name
- P3E (NCT05774522)
- Testing
- Measurement of pharyngeal critical airway closing pressure, Acoustic pharyngometry, Upper airway ultrasound
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ankyloglossia, Speech Delay
Frenuloplasty for Speech and Myofunctional Outcomes
Children with ankyloglossia (tongue tie) can have abnormal tongue function, putting them at a disadvantage when it comes to speech and articulation.
- Conditions
- Ankyloglossia, Speech Delay, Dentofacial Abnormalities
- Trial name
- NCT06089629
- Testing
- Lingual frenuloplasty
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Oregon Clinic
Cerebral Palsy, Functioning
Effects of Action Observation Therapy and Mirror Therapy in Children With Unilateral Cerebral Palsy
The aim of this study was to examine the effects of action observation therapy and mirror therapy on upper extremity functions in children with unilateral cerebral palsy.
- Conditions
- Cerebral Palsy, Functioning, Upper Extremity Problem
- Trial name
- NCT05951829
- Testing
- Action Observation Therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke
Feasibility of a Home Hazard Management Program for Malaysian Stroke Survivors
This quasi experimental design study aims to examine the feasibility and potential effectiveness of a home hazard management program to reduce the rate of falls and fear of falling among Malaysian community dwelling stroke…
- Trial name
- NCT04618029
- Testing
- Home Modification, Education
- Where
- 3 sites in Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Putra Malaysia
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
PKU, Phenylketonurias
Market Research - Acceptability Trial for a New PKU Amino Acid Based Protein Substitute
The aim of this study is to demonstrate that a new protein substitute is acceptable and well tolerated in children with PKU.
- Conditions
- PKU, Phenylketonurias, Inborn Errors of Metabolism, Metabolic Disease
- Trial name
- NCT04309331
- Testing
- Motion
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Dr. Schär AG / SPA
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