Clinical trials: Neuralgia Peripheral
Neuropathic Pain
Balance and Gait on Neuropathic Pain Due to Lumbar Disc Degeneration
Chronic lumbar neuropathic pain, characterized by pain, numbness, tingling and muscle weakness in the lower extremities, is one of the most common neuropathic pain syndromes.
- Trial name
- NCT05223439
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cervicogenic Headache, Central Sensitization
Central Sensitization and Neuropathic Pain in Cervicogenic Headache
Cervicogenic headache is a type of secondary headache that originates from the structures of the neck and can spread toward the head and facial regions.
- Conditions
- Cervicogenic Headache, Central Sensitization, Neuropathic Pain
- Trial name
- NCT07292181
- Testing
- Clinical assessment with standardized questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Sciatica
Pain Relief by Platelet-rich Plasma (PRP) Treatment
Past PRP therapy is not sufficient for some part of patients.In this clinical research, The integrated application of PRP with extracellurar matrix and some type of stem cell technique.
- Trial name
- NCT01749839
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint Bernard Mission University
Herpes Zoster, Postherpetic Neuralgia
Shingles Prevention Study
The incidence and severity of HZ (or shingles), as well as the frequency and severity of its complications, increases markedly with increasing age. More than half of all cases occur in persons over the age of 60.
- Trial name
- SPS (NCT00007501)
- Testing
- Varicella-zoster vaccine
- Where
- 22 sites in United States
- Volunteers
- 38,456 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Neuropathic Pain, Peripheral Neuropathy
Axon Therapy for Post-Traumatic Peripheral Neuropathic Pain Compared to Conventional Medical Management
Compare Axon Therapy using transcutaneous magnetic stimulation (tMS) against conventional medical management in treating post-traumatic peripheral neuropathic pain (PTPNP).
- Trial name
- NCT04795635
- Testing
- CMM + Axon Therapy
- Where
- 3 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- NeuraLace Medical, Inc.
Spinal Cord Injury + Peripheral Nerve Diseases
Assessment of Neuropathic Pain
Development of neuropathic pain is one of the most disabling sequels after spinal cord injury (SCI) and in peripheral nerve diseases.
- Trial name
- NCT02138344
- Where
- Switzerland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Diabetes Mellitus (DM)
Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy
This research is structured as a cross-sectional observational study. The primary objective is to compare central sensitization across painful and painless phenotypes of diabetic peripheral neuropathy.
- Trial name
- NCT07316322
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Inonu University
Dorsal Root Ganglion
Magnetic Resonance Neurography Analysis of Healthy Human Thoracic Dorsal Root Ganglion
Here, this study aimed to conduct magnetic resonance neurography (MRN) of the thoracic DRGs in a cohort of healthy individuals. The acquired images will be thoroughly analyzed utilizing 3D-slicer software.
- Trial name
- NCT06177379
- Testing
- healthy volunteer
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Pain, Neuropathic
Gabapentin and Donepezil Combination on Experimental Human Pain Models
This study will compare the effects of gabapentin alone, and gabapentin + donepezil given together in two types of experimental electrical pain tests in up to 48 healthy male subjects (after 24 recruited in the first cohort an…
- Trial name
- NCT01485185
- Testing
- Gabapentin lower dose, Donepezil, Gabapentin higher dose
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Painful Lumbar Radiculopathy, Healthy
Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin)
The primary objective of the study is to evaluate the safety and tolerability of a range of single intravenous (IV) and subcutaneous (SC) doses of BG00010 in healthy volunteers, and a range of multiple SC doses of BG00010 in…
- Trial name
- NCT01842126
- Testing
- BG00010 IV, BG00010 SC
- Where
- Netherlands
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Biogen
Behcet's Disease, Central Sensitisation
Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease
There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance and decreased quality of life in Behçet's disease.
- Trial name
- NCT03531385
- Testing
- Central sensitisation, Neuropathic pain, Sleep disturbance
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Neuropathic Pain, Radiculopathy, Cervical
Evaluation of Neuropathic Pain in the Context of Clinical Symptoms, Quantitative Sensory Tests and Imaging With FMRI
This study is planned to evaluate patients with upper extremity neuropathic pain due to cervical radiculopathy with clinical symptoms, Quantitative Sensory Testing(QST) and Functional Magnetic Resonance Imaging(fMRI).
- Trial name
- NCT03890315
- Testing
- Functional MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Healthy Volunteer
Evaluating the Safety, Tolerability, and Pharmacokinetics of BIIB095 in Healthy Participants
The primary objective of the study is to evaluate the safety and tolerability of single- and multiple-ascending oral doses of BIIB095 in healthy participants.
- Trial name
- NCT03454126
- Testing
- BIIB095
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biogen
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Piriformis Muscle Syndrome, Anthropometry
Pelvic and Hip Morphometry in Piriformis Syndrome
In this case-control study, 23 patients diagnosed as PS by diagnostic injection with ultrasound guidance were selected as the study group.
- Trial name
- NCT04600024
- Testing
- Ultrasound guided diagnostic injection
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Neuropathic Pain, PTSD
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants.
- Trial name
- NCT06414356
- Testing
- Ketamine, Magnesium sulfate, Ketamine + Magnesium sulfate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Margaux M. Salas, PhD
Spinal Cord Injuries, Neuropathic Pain
Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
Many adults with spinal cord injury (SCI) suffer from long-term debilitating neuropathic pain. Available treatments, including opioids, are ineffective at eliminating this pain.
- Trial name
- NCT04706208
- Testing
- Cognitive Multisensory Therapy, Usual Care, Clinical Assessment
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sciatica
PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients
The purpose of this study is to see if the spine shows areas of inflammation using a specific type of imaging (pictures).
- Trial name
- NCT02130271
- Testing
- Radioactive dye, PET/MRI, Blood draw
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Neuropathic Pain
Cortical Plasticity After Motor Cortex Stimulation in Healthy Subject and Chronic Pain Patients
The primary aim of this study is to evaluate the induction of sensory-motor cortex plasticity after motor cortex stimulation in healthy subjects, using laser-evoked nociceptive cortical potentials, and in chronic neuropathic pain…
- Trial name
- NCT02849834
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Chronic Sciatica
Efficacy and Mechanism of Acupuncture for Chronic Sciatica Using fMRI
This research is planned to build a basis about the efficacy and mechanism of acupuncture on pain and emotional disorder in patients with chronic sciatica using fMRI.
- Trial name
- NCT03350789
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong