Clinical trials: Neurally Adjusted Ventilatory Assist
Mechanical Ventilator Weaning, Critically Ill
Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Children
The goal of this clinical trial is to compare weaning from mechanical ventilation in critically ill children. The main questions it aims to answer are: Will weaning with neurally adjusted ventilatory assist (NAVA) mode…
- Conditions
- Mechanical Ventilator Weaning, Critically Ill, Mechanical Ventilation, Neurally Adjusted Ventilatory Assist
- Trial name
- NCT06157593
- Testing
- NAVA
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Acute Lung Injury, Mechanical Ventilation
NAV-ALI: Neurally Adjusted Ventilatory Assist in Patients Recovering Spontaneous Breathing After Acute Lung Injury
Evaluation of a new ventilatory mode Neurally Adjusted Ventilatory Assist "NAVA" in patients who recover spontaneous breathing after acute lung injury.
- Trial name
- NCT00963066
- Testing
- PSV - pressure suppot ventilation, NAVA - Neurally Adjusted Ventilatory Assist, NAVA - EMG
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Neonatal Oxygen Desaturation, Premature
Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants
This research study is being done to investigate the effect of changing an infant's body position on how hard the baby works to breathe, the baby's oxygen level, the baby's carbon dioxide level, the baby's lung volume, the baby's…
- Conditions
- Neonatal Oxygen Desaturation, Premature, Ventilator Lung; Newborn, Apnea of Prematurity
- Trial name
- NCT05968586
- Testing
- Body positioning
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
Bronchiolitis
Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis
This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy…
- Trial name
- NCT06053684
- Testing
- Standard Non-Invasive Mechanical Servo Ventilation, Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Montefiore Medical Center
Hernia, DIaphragmatic, Congenital
Work of Breathing Description in Neonates With Congenital Diaphragmatic Hernia in NAVA and in Conventional Ventilation.
Congenital diaphragmatic hernia (CDH) is a congenital malformation associated with significant mortality and respiratory morbidity, particularly related to prolonged mechanical ventilation.
- Trial name
- NAVA-DIAPH (NCT03250793)
- Testing
- Physiologic study measuring work of breathing which can be estimated by the esophageal and trans-diaphragmatic pressure-time product obtained by an esophageal transducer
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Hospices Civils de Lyon
ALI/ARDS Patients
Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients: Pressure Support Ventilation (PSV), Neurally Adjusted Ventilatory Assist (NAVA) and Controlled by Patient
The investigators' aim is to study the effect of pressure support ventilation versus neurally adjusted assist (NAVA) and controlled by patient in mechanically ventilated ALI/ARDS subjects.
- Trial name
- NCT00576771
- Testing
- PSV, NAVA, patient-controlled
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Policlinico Hospital
Healthy
Non-invasive Neurally Adjusted Ventilatory Assist in Healthy Volunteers
Neurally adjusted ventilatory assist (NAVA) is a new concept of mechanical ventilation. NAVA delivers assistance to spontaneous breathing based on the detection of the electrical activity of the diaphragm.
- Trial name
- NCT00941044
- Testing
- Neurally adjusted ventilatory assist
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pediatric Acute Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure
It is hypothesized that the use of Neurally Adjusted Ventilatory Assist (NAVA) compared to pressure support to provide noninvasive ventilation to children will result in a decrease in the number of children with moderate to…
- Trial name
- NiNAVAped (NCT01873521)
- Testing
- Non invasive ventilation
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Hospital Universitario La Paz
Acute Respiratory Failure
NAVASET: Nava Level Titration Using Comfort Scales
Determining the optimal Neurally Adjusted Ventilatory Assist (NAVA) level remains challenging, and several methods have been suggested. However none of them seems easily utilisable.
- Trial name
- NCT02133443
- Testing
- PSV - pressure support ventilation, Neurally Adjusted Ventilatory Assist
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
ARDS, Human, Mechanical Ventilation Pressure High
Lung Protection in ARDS Using Neurally Adjusted Ventilatory Assist
The aim of this study is to investigate the use neurally adjusted ventilatory assist (NAVA) as lung protective strategy in patients with acute respiratory distress syndrome (ARDS).
- Trial name
- NAVA (NCT03868982)
- Testing
- Neurally adjusted ventilatory assist
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Fu Jen Catholic University
Respiratory Failure
Performance of Neurally Adjusted Ventilatory Assist (NAVA) During Spontaneous Breathing Trial
The purpose of this study is to compare a new mode of mechanical ventilation (NAVA, or Neurally adjusted Ventilatory assist) with a traditional mode (Pressure Support ventilation) on its the ability to detect patients ready for…
- Trial name
- NCT01337271
- Testing
- SBT- PSV, SBT - NAVA
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Obstructive Lung Diseases
Can NAVA Mode Reduce Mechanical Ventilation Day in Patients With COPD ?
Background： Neurally Adjusted Ventilatory Assist (NAVA) mode is a new mode of ventilator, using electronic potential of diaphragm to adjust tidal volume.
- Trial name
- NCT05595733
- Testing
- Ventilator mode
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Fu Jen Catholic University Hospital
Acute Respiratory Failure
Study Comparing Two Ventilation Modes NAVA (Neurally Adjusted Ventilatory Assist) Mode and Spontaneous Breathing With Inspiratory Pressure Support (IPS) Mode in Consecutive Patients Hospitalized for Acute Respiratory Failure Requiring Mechanical Ventilation With Endotracheal Tube.
This is a multicenter, prospective, randomized, open-label study which compared two ventilation modes: spontaneous NAVA mode and spontaneous breathing with IPS mode (the latter is considered as the reference ventilatory mode) in…
- Trial name
- NCT02018666
- Testing
- NAVA endotracheal tube
- Where
- 11 sites in France
- Volunteers
- 129 people
- Sponsor
- Clinact
Acute Respiratory Failure
Noninvasive NAVA Versus Flow-triggered Noninvasive Pressure Support in Pediatric Respiratory Failure
Acute Hypoxemic Respiratory Failure (AHRF) is a leading cause of admission in Pediatric Intensive Care Unit (PICU). Traditional treatment includes endotracheal intubation and mechanical ventilation, that are invasive and not free…
- Trial name
- NCT03697863
- Testing
- Noninvasive Respiratory Support
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Acute Respiratory Failure, Mechanical Ventilation Complication
New Setting of Neurally Adjusted Ventilatory Assist During Mask Noninvasive Ventilation
Non invasive ventilation (NIV) is generally delivered by pneumatically triggered and cycled-off Pressure Support (PSP) through a facial mask.
- Trial name
- NCT03041402
- Testing
- PSP, NAVA, PSN
- Volunteers
- 14 people
- Sponsor
- Southeast University, China
Congenital Diaphragmatic Hernia
Neurally Adjusted Ventilatory Assist for Neonates With Congenital Diaphragmatic Hernias
Congenital Diaphragmatic Hernias (CDH) are typically repaired surgically in the first few days of a neonate's life. Following surgical repair, infants usually require ventilatory support to ensure adequate oxygenation.
- Trial name
- NAN-C (NCT05839340)
- Testing
- Neurally Adjusted Ventilatory Assist, Assist Control Ventilation
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- King's College Hospital NHS Trust
Respiratory Insufficiency, Acute Respiratory Insufficiency
NIV-NAVA vs NIV-PS/PC in Respiratory Insufficiency
This study evaluates the difference between Non Invasive Ventilation with Neurally Adjusted Ventilatory Assist (NIV-NAVA) and Conventional Non Invasive Ventilation with Pressure Support (PS) or Pressure Control (PC).
- Trial name
- NCT02592512
- Testing
- NIV-NAVA, NIV-PS/PC
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Vejle Hospital
Newborn Morbidity
Effect of Changing Levels of Neurally Adjusted Ventilatory Assist (NAVA) in Newborns
To examine the effect of changing levels of support during NAVA-ventilation ("NAVA-level") on electrical diaphragm activity of the newborn on invasive or non-invasive NAVA ventilation.
- Trial name
- NCT03780842
- Testing
- NAVA level
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Julie Lefevere
Acute Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) Study in Adults With Acute Respiratory Failure
The purpose of this study is to compare a specific mode of artificial ventilation (help from a breathing machine) with other modes.
- Trial name
- NCT01730794
- Testing
- NAVA ventilation, Conventional Lung Protective Ventilation
- Where
- 14 sites in China, Spain
- Volunteers
- 306 people
- Sponsor
- Massachusetts General Hospital
Postoperative Patients
Diaphragmatic Activity During Weaning With NAVA, a Pilot Study (NAVA: Neurally Adjusted Ventilatory Assist)
The purpose of this study is to describe the diaphragm electromyographic activity (Edi) in healthy lung patients due to obtain a reference to guide the weaning in those patients
- Trial name
- NAVA (NCT03027713)
- Testing
- weaning protocol
- Volunteers
- 40 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia