Clinical trials: Neurodevelopmental Disability
Developmental Disability
Self-identified Participation and Environment of Children With Disabilities
Picture My Participation (PmP) is a child self-report tool for children and adolescents with disabilities. The PmP uses pictures that enable children to identify participation frequencies, participation goals, and environmental…
- Trial name
- NCT04522518
- Testing
- PmP-C App
- Where
- Taiwan
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Cognition Disorder, Brain Mapping
Facilitating Numerical Processing With Transcranial Stimulation in Developmental Dyscalculia
Background: Developmental dyscalculia is a learning disability in which individuals have difficulty learning or comprehending mathematics or other number concepts (such as keeping score during games, measuring time, or estimating…
- Trial name
- NCT01195961
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Urinary Incontinence
Toilet Training and Adults With Learning Disabilities
Incontinence is common in adults with learning disabilities (LDs). Behavioural toilet training in conjunction with toilet alarms is recommended for people with LDs, but there is a paucity of research, thus evidence-based…
- Trial name
- NCT05626062
- Testing
- Toilet alarm
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Glasgow Caledonian University
Autism
MRI Study of Cerebral Blood Flow in Development Disorders in Children
The purpose of this study is reproduce the individual detection results by PET with Arterial Spin Labeling (ASL) MRI, to establish a biomarker useful in autism diagnosis.
- Trial name
- IRM-Aut (NCT02165410)
- Testing
- ASL-MRI, Diffusion tensor imaging (diffusion MRI), Resting state MRI
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Reading Learning Disability, Math Learning Disability
Improving the Academic Performance of First-Grade Students With Reading and Math Difficulty
The main purpose of this clinical trials is to explore short-term effects of coordinated intervention versus the business-as-usual school program on the primary endpoints of post-intervention word-reading fluency and arithmetic…
- Trial name
- NCT03991234
- Testing
- Reading Intervention, Math Intervention, Coordinated Intervention
- Where
- United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Depression, Autism
Implementation of the Parents Taking Action in Paraguay
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism…
- Trial name
- PTA-Paraguay (NCT05780138)
- Testing
- Parents Taking Action
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Family Conflict, Marital Conflict
Families of Youth with Developmental Disabilities: a Theory-Based Intervention
This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and/or developmental disability.
- Conditions
- Family Conflict, Marital Conflict, Communication
- Trial name
- NCT03495440
- Testing
- Center Sessions, At-home
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Neurodevelopmental Disabilities, Emotional Regulation
Emotional Regulation in Children With ND: the Role of Genomic Variation, Proteomic Patterns, and Early Experience
Children with neurodevelopmental disabilities (ND) represent an heterogeneous population characterized by a wide range of clinical diagnoses (e.g., cerebral palsy, sensory impairment, psychomotor retardation), which are…
- Conditions
- Neurodevelopmental Disabilities, Emotional Regulation, Epigenetics, Parental Factors
- Trial name
- NCT05004090
- Testing
- DNA methylation analysis, Proteomics analysis, Still Face Paradigm
- Where
- Italy
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Disabilities, Psychological Wellbeing
90SecondParent Wellbeing: Weekly Health Letters for Parents of Children With Developmental Disabilities
Parents of children with developmental disabilities (DD) consistently report significant psychological distress, a vulnerability amplified during the COVID-19 pandemic due to intensified caregiving demands and reduced access to…
- Conditions
- Developmental Disabilities, Psychological Wellbeing, Parental Wellbeing
- Trial name
- NCT07869251
- Testing
- 90SecondParent Wellbeing
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Therapeutic Recreation, Intellectual Disability
The Effects of Therapeutic Recreation Activities on Aberrant Behaviours of Individuals With Intellectual Disabilities
The aim of this study was to determine the effect of Therapeutic Recreation Activities on Aberrant Behavior of Adolescents With Intellectual Disabilities.
- Conditions
- Therapeutic Recreation, Intellectual Disability, Recreational Activities, Aberrant Behaviors
- Trial name
- NCT04546464
- Testing
- Therapeutic Recreation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Intellectual Disability
Improving the Health of Parents and Their Adolescent and Transition-age Youth With Intellectual and Developmental Disabilities
This study will determine the comparative effectiveness of Go Act, a tailored advocacy curriculum versus Peer parent-directed peer learning for increasing parent activation for parents of youth with intellectual and developmental…
- Trial name
- NCT05986305
- Testing
- Go Act, Peer
- Where
- 2 sites in United States
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Speech and Language Disorder, Speech Therapy
Providing Speech Therapy Awareness in Private Schools
There has been limited research in the area of speech and language therapy awareness in Pakistan. The study aims to assess the efficacy of providing speech therapy awareness in private schools through a pre-post model.
- Conditions
- Speech and Language Disorder, Speech Therapy, Speech Delay, Swallowing Disorder
- Trial name
- NCT04505696
- Testing
- Speech-Language Pathology Presentation
- Where
- Pakistan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Disorders and Maternal Stress, Development Delay
Perinatal Autism Genetics and Epigenetics Study
The University of Iowa's Center for Disabilities and Development is researching how pregnancy, early childhood experiences, and genetic factors influence child development, with a focus on autism spectrum disorder (ASD).
- Conditions
- Autism Disorders and Maternal Stress, Development Delay, Prenatal Stress, Social Behavior
- Trial name
- PAGES (NCT07738003)
- Testing
- Change in child's DNA methylation, Perinatal stress, Early social experience
- Where
- United States
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Developmental Disability, Autism Spectrum Disorder
Association Between Motor Skills and Sensory Profiles in Children With Typical and Atypical Development Aged 4 to 11 Years
Background and Justification Childhood developmental disorders, such as Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), and Developmental Coordination Disorder (DCD), pose significant challenges…
- Conditions
- Developmental Disability, Autism Spectrum Disorder, Development Coordination Disorder, Attention Deficit Disorder With Hyperactivity
- Trial name
- MOTISEN (NCT06764810)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Fragile X Syndrome
CTH120 First-in-Human Study: Single and Multiple Ascending Doses and Potential Food Interaction
The purpose of this First-in-Human Phase I study is to investigate the safety, tolerability and pharmacokinetics of CTH120 in adult healthy volunteers.
- Trial name
- FIH-CTH120 (NCT06480968)
- Testing
- CTH120
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Connecta Therapeutics, S.L.
Child Development Disorder
Postural Control Among Children with and Without Dyslexia
As Chinese-speaking children with dyslexia typically have different cerebellar sign behavior from non-Chinese-speaking counterparts, this study compared the effect of visual occlusion on the static balance between dyslexic and…
- Trial name
- NCT05072418
- Testing
- Eye-opened and Eye-closed
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Depressive Symptoms
Implementation of Bright Light Therapy ID
Many adults with intellectual disabilities (ID) have depressive symptoms, which negatively impact their quality of life. A lot of of the non-medicinal forms of treatment are not or hardly suitable for people with ID.
- Trial name
- NCT06215235
- Testing
- Bright light therapy
- Where
- Netherlands
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Dyslexia
Dyslexics' Visual Attention Field
dyslexia is often considered like a phonological deficit but some researches show that a visual attention (V-A) deficit can occur in dyslexia.
- Trial name
- NCT03285789
- Testing
- Passing tests in dyslexics with reduced eva, Passing tests in controls
- Where
- France
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon