Clinical trials: Neurodevelopmental Disability
Motor Coordination or Function; Developmental Disorder
A Multiple Baseline Design Study to Investigate the Effectiveness of OT-SI Using an Intensive Intervention Model
The investigators hypothesize that children completing 30 sessions of occupational therapy using a sensory integration approach (OT-SI) will demonstrate positive changes in outcome measures related to motor coordination…
- Trial name
- NCT03355417
- Testing
- OT-SI
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Virginia Commonwealth University
Language Development Disorders
Improving STEM Outcomes for Young Children With Language Learning Disabilities Via Telehealth
In this study the investigators focus on a subset of at-risk students who find the language of science to be a barrier to the learning of science. These are the nearly 3 million children in the U.S.
- Trial name
- NCT04775199
- Testing
- Language Intervention
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Karla McGregor
Down Syndrome
Effect of Neuro Developmental Therapy in Infants With Down Syndrome
Neurodevelopmental treatments are a progressive therapeutic method experienced thru qualified therapists for the improvement in affected ones.
- Trial name
- NCT04816409
- Testing
- conventional therapy, Neurodevelopmental therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Intellectual Disability, Mild
Evaluation of CO-OP for Adolescents With Mild Intellectual Disability
Intellectual disability (ID) affects a person throughout life and includes difficulties to manage what is expected in everyday life based on age.
- Trial name
- CO-OPIF (NCT06691698)
- Testing
- The Cognitive Orientation to Daily Occupational Performance Approach
- Where
- 2 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Autism Spectrum Disorders
Dialectical Behavior Therapy for Adults With Autism Spectrum Disorders
Dialectical Behavior Therapy (DBT; Linehan, 1993) effectively diminishes emotion dysregulation and self-harm behaviors in a number of disorders.
- Trial name
- Autisemo (NCT04737707)
- Testing
- Dialectical Behavior Therapy (DBT)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Strasbourg, France
Reading Learning Disability, Math Learning Disability
Improving the Academic Performance of First-Grade Students With Reading and Math Difficulty
The main purpose of this clinical trials is to explore short-term effects of coordinated intervention versus the business-as-usual school program on the primary endpoints of post-intervention word-reading fluency and arithmetic…
- Trial name
- NCT03991234
- Testing
- Reading Intervention, Math Intervention, Coordinated Intervention
- Where
- United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Pediatric Disorder, Disability, Developmental
Hybrid Telehealth in Pediatric Physical Therapy
The purposes of this study are to compare the impact of a hybrid of telehealth and in-person physical therapy services to in-person services alone on the in-home functional skills of children with moderate to severe disability.
- Trial name
- NCT05350904
- Testing
- Hybrid of telehealth and in-person physical therapy services
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Depression, Autism
Implementation of the Parents Taking Action in Paraguay
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism…
- Trial name
- PTA-Paraguay (NCT05780138)
- Testing
- Parents Taking Action
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Pathology
Different Clinicopathological Features of Non-Elderly Sigmoid Volvulus Patients
Sigmoid volvulus is frequently seen in male patients over 60 years old. In the sigmoid volvulus <60 age groups, the male/female ratio is close to each other.
- Trial name
- NCT04360525
- Testing
- Reasons
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Family Conflict, Marital Conflict
Families of Youth with Developmental Disabilities: a Theory-Based Intervention
This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and/or developmental disability.
- Conditions
- Family Conflict, Marital Conflict, Communication
- Trial name
- NCT03495440
- Testing
- Center Sessions, At-home
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Neurodevelopmental Disabilities, Emotional Regulation
Emotional Regulation in Children With ND: the Role of Genomic Variation, Proteomic Patterns, and Early Experience
Children with neurodevelopmental disabilities (ND) represent an heterogeneous population characterized by a wide range of clinical diagnoses (e.g., cerebral palsy, sensory impairment, psychomotor retardation), which are…
- Conditions
- Neurodevelopmental Disabilities, Emotional Regulation, Epigenetics, Parental Factors
- Trial name
- NCT05004090
- Testing
- DNA methylation analysis, Proteomics analysis, Still Face Paradigm
- Where
- Italy
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Immunodeficiency, Skeletal Abnormalities
European Alpha-Mannosidosis Participant
International, multicenter, observational, longitudinal monitoring study to investigate the prevalence of Alpha-Mannosidosis in participants at risk for Alpha-Mannosidosis.
- Conditions
- Immunodeficiency, Skeletal Abnormalities, Deafness, Mental Retardation
- Trial name
- EUMAP (NCT03651245)
- Where
- 19 sites in Germany, Switzerland
- Volunteers
- 667 people
- Sponsor
- CENTOGENE GmbH Rostock
Intellectual Disability
Computerized Testing System for Measuring Motor and Sensory Integrative Functions in Intellectual Disabilities
Assessment of the motor and sensory integrative functions (MSI) is a key component of an overall health and functional evaluation for school-aged children with intellectual disabilities (ID).
- Trial name
- NCT05473377
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Dyslexia
Working Memory Training for Children With Dyslexia
The main aim of this interventional study is to investigate whether the effects of computerized working memory training improves reading abilities for children, i.e. ages 9 - 16 years, diagnosed with dyslexia.
- Trial name
- NCT02429739
- Testing
- Working memory Training
- Where
- Norway
- Volunteers
- 32 people
- Sponsor
- Sorlandet Hospital HF
Neurodevelopmental Disorders, Developmental Disabilities
Family Networks (FaNs) for Children With Developmental Disorders and Delays
Over 6% of children in Pakistan suffer from a developmental disorder (intellectual disability or Autistic spectrum disorder) and most receive no intervention.In an earlier proof of concept study, the investigators integrated…
- Trial name
- FaNs (NCT02792894)
- Testing
- Family networks program
- Where
- Pakistan
- Volunteers
- 540 people
- Sponsor
- Human Development Research Foundation, Pakistan
Developmental Disabilities, Psychological Wellbeing
90SecondParent Wellbeing: Weekly Health Letters for Parents of Children With Developmental Disabilities
Parents of children with developmental disabilities (DD) consistently report significant psychological distress, a vulnerability amplified during the COVID-19 pandemic due to intensified caregiving demands and reduced access to…
- Conditions
- Developmental Disabilities, Psychological Wellbeing, Parental Wellbeing
- Trial name
- NCT07869251
- Testing
- 90SecondParent Wellbeing
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Intellectual Disability
Physical Activity With Tailored E-health Support for Individuals With Intellectual Disability
The main objective of this project is to enhance physical activity in youths and adults with intellectual disabilities (IDs) by developing and testing a tailored e-heath support for motivation and participation in physical…
- Trial name
- PA-IDe (NCT04079439)
- Testing
- Physical activity with tailored e-health support
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital of North Norway
Global Developmental Delay, Cerebral Palsy
Predicting Developmental Disability Type and Mental Retardation Level in Children With General Developmental Delay
The purpose of this study is to find the relationship between the stage and quality of developmental delay during infancy and toddler age, and the final diagnosis that the child gets a few years later (MR, type of PDD, CP or…
- Conditions
- Global Developmental Delay, Cerebral Palsy, Mental Retardation, Pervasive Developmental Disorders
- Trial name
- NCT01430845
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Adolescent Behavior, Intellectual Disability
Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities
The objective of this study is to compare the effect of two strategies to increase MVPA in adolescents with intellectual and developmental disabilities (IDD): a single level intervention delivered to the adolescent only, and a…
- Conditions
- Adolescent Behavior, Intellectual Disability, Down Syndrome, Physical Activity
- Trial name
- NCT03684512
- Testing
- Group Exercise Sessions, Individual Support Sessions, Facebook Group
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Kansas
Developmental Disability, Autism Spectrum Disorder
The Effects of Virtual Zumba® in Individuals With Developmental Disabilities
There are critical knowledge gaps that need to be addressed to understand the impact of aerobic exercise programs on relevant functional outcomes in adults with developmental disabilities (DD).
- Conditions
- Developmental Disability, Autism Spectrum Disorder, Down Syndrome, Cerebral Palsy
- Trial name
- NCT05198232
- Testing
- Zumba High Tempo, Zumba Low Tempo
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Auburn University
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