Clinical trials: Neurodevelopmental Disorder
Developmental Coordination Disorder
The Effects of a Group-based Gaze Training Intervention for Children With Developmental Coordination Disorder
The aim of this study was to integrate a gaze training intervention (i.e., quiet eye training; QET) that has been shown to improve the throwing and catching skill of children with Developmental Coordination Disorder (DCD), within…
- Trial name
- NCT02904980
- Testing
- Technical Training, Quiet Eye Training
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder
Evaluating the Validity of a Genetic Risk Assessment Tool in Identifying Autism Spectrum Disorder
There are three purposes to this study. The first purpose is to evaluate the value of a genetic test in determining risk for autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Developmental Delay
- Trial name
- NCT01452061
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Thomas W. Frazier, Ph.D
Phelan-McDermid Syndrome, Autism Spectrum Disorder
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments.
- Conditions
- Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
- Trial name
- NCT02461420
- Where
- 5 sites in United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Development, Infant, Development, Language
Early Neurophysiological Markers of Language Impairments
The present project aims at identifying very early electrophysiological risk markers for language impairments. The long-term goals of the study include the characterization of learning developmental trajectories in children at…
- Conditions
- Development, Infant, Development, Language, Developmental Language Disorder, Learning Disabilities
- Trial name
- NCT05767242
- Testing
- Electrophysiological recording, Behavioral assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Attention Deficit Hyperactivity Disorder
Pharmacogenetic Studies on Attention Deficit Hyperactivity Disorder
The ultimate goal of this study is to find the association between specific polymorphism of candidate genes and medication response in attention deficit hyperactivity disorder (ADHD) patients.
- Trial name
- NCT00916786
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Separation Anxiety Disorder, Generalized Anxiety Disorder
Acoustic Neuromodulation (ANM) for Youth With Anxiety Disorders
The acoustic neuromodulation trial (ANM-T) is a two-phase, single-site, pilot randomized clinical trial examining the feasibility of completing a larger scale efficacy study of a novel treatment of non-linear modulated acoustic…
- Conditions
- Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia
- Trial name
- ANM (NCT02572973)
- Testing
- Acoustic Neuromodulation (ANM)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Attention Deficit Hyperactivity Disorder (ADHD)
Neurophysiological Attention Test (NAT) for Objective Assessment of Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is develop a new assessment tool for Attention Deficit-Hyperactivity Disorder (ADHD) and to then test its validity (i.e. ability to discriminate between individuals with ADHD and healthy controls).
- Trial name
- NAT-I (NCT02407496)
- Testing
- Behavioral assessment and NAT EEG tests
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Think Now Incorporated
ADHD
Classroom Behavior Support (CBS) Project
The goal of the study is to conduct a randomized clinical trial to evaluate the impact of the Classroom Behavior Support Program (CBS; a multi-component, individually-tailored teacher consultation program) on teachers' classroom…
- Trial name
- CBS (NCT05137327)
- Testing
- Classroom Behavior Support (CBS) Condition, Standard Problem Solving Consultation
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ohio University
Autism
Sensory Phenotypes of Autism Spectrum Disorder
This project plans to establish sensory phenotypes of a Taiwanese ASD cohort across lifespan, including variety of sensory modalities, sensory domains, and clinical correlates.
- Trial name
- NCT05829161
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
GABA Pathways in Autism Spectrum Disorder (ASD)
This study investigates the brain response to a single acute dose of a GABAa receptor acting drug (Benzodiazepine or positive allosteric modulator) compared to a single dose of placebo in adults with and without autism spectrum…
- Trial name
- NCT03678129
- Testing
- AZD7325_10, AZD7325_20, Clobazam
- Where
- United Kingdom
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- King's College London
Communication Disorder, Social
Roll for Intervention - TBI Group Treatment
Communication group intervention for individuals with Traumatic Brain Injury based on INSIGHT protocol (Keegan et al, 2020) with roll playing game focus
- Trial name
- NCT05517161
- Testing
- INSIGHT
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Moravian University
Autism Spectrum Disorder
Comprehensive Communication Intervention for Minimally Verbal Children With Autism
Overview The goal of Comprehensive Communication Intervention for Minimally Verbal Children with Autism is to conduct an efficacy study of a promising intervention to increase spoken language in preschool children who are…
- Trial name
- NCT02291172
- Testing
- Intervention JEP
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Autism Spectrum Disorder
Emotional Proactive Brain Study in Adults With Autism Spectrum Condition
This project aims: to study behavioral and cerebral activity specificity (latency and amplitude of evoked potentials, time frequency maps and cerebral connectivity) in predictive process (top-down regulation) during visual…
- Trial name
- PREDEMAUT (NCT04069676)
- Testing
- EEG
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Autism Spectrum Disorder, Typical Development
Improving Social Interaction for Adolescents With Autism During the Transition to Adulthood
This study compares the efficacy of two intervention strategies for improving social outcomes for autistic adolescents and young adults when interacting with unfamiliar non-autistic peers.
- Trial name
- NCT03785327
- Testing
- tDCS, Autism Training
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Developmental Disabilities, Developmental Delay
Exploratory Trial of a Pediatric Web-Based Care Planning Guide
Infants and toddlers with developmental disabilities or delays use early intervention (EI) for rehabilitation services. Yet, poor quality of EI services is pervasive, particularly for racially and ethnically diverse and socially…
- Trial name
- PROSPECT+ (NCT06458959)
- Testing
- PEM+
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Autism Spectrum Disorder
Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice
The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test…
- Trial name
- AUTICOPP (NCT04638452)
- Testing
- Video & movements recording, Questionnaires
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
ADHD, Parenting
Helping Toddlers and Parents Together
Using stakeholder feedback (i.e., behavioral health providers \& caregivers), the goal of this study is to develop a behavioral parenting program that focuses on both parent mental health and parenting for parents of toddlers…
- Trial name
- NCT04864808
- Testing
- Behavioral Parent Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Adhd
Psychostimulants Effects on Brain Functional Connectivity in Youth With Attention Deficit Hyperactivity Disorder
In the current study, we will administer three widely administered cognitive tasks while simultaneously measuring electroencephalography (EEG) in ADHD patients before and after methylphenidate immediate release (IR) treatment…
- Trial name
- NCT02318017
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Neurodevelopmental Disorders
WHO Mental Health Gap Action Program (mhGAP) for Improving Child Mental and Behavioral Disorder Service Quality in China
The goal of this clinical trial is to learn if the adapted mhGAP intervention guide (mhGAP-IG) can improve quality of child mental and behavioral disorders (CMBDs) services in China.
- Trial name
- mhGAP (NCT06702410)
- Testing
- mental health gap action program intervention guide (mhGAP-IG)
- Where
- 9 sites in China
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Healthy Volunteers, Drug Users
A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users
This single-center study will be a single-dose, randomized, double-blind, placebo- and active-controlled crossover study with a single inpatient treatment visit.
- Trial name
- NCT02144415
- Testing
- EB-1020 400 mg, EB-1020 800 mg, lisdexamfetamine 150 mg
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
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