Clinical trials: Neurodevelopmental Impairment
Sensation Diminished, Pinprick, Pain
Tactile and Pain Sensory Thresholds and Hand Grip Strength
The aim of this study was to compare fingertip tactile sensation, hand and finger grip strength, and hand pain thresholds in children diagnosed with specific learning disorder with impairment in written expression and healthy…
- Conditions
- Sensation Diminished, Pinprick, Pain, Specific Learning Disorder, With Impairment in Written Expression
- Trial name
- NCT07533409
- Testing
- Treatment outcome
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sultan 1. Murat State Hospital
Asphyxia Neonatorum, Neonatal Mortality
Neonatal Resuscitation in Zambia
Asphyxia is a leading cause of neonatal death in Zambia. This study will be conducted in two cities in Zambia to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared to the new World…
- Conditions
- Asphyxia Neonatorum, Neonatal Mortality, Hypoxic Ischemic Encephalopathy
- Trial name
- NCT00097097
- Testing
- Neonatal Resuscitation
- Where
- Zambia
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Attention Deficit Hyperactivity Disorder
A Naturalistic Study of Functional Impairment for Individuals With ADHD in the Early Morning and Late Afternoon/Evening Hours
The objective of this study is to assess the burden and impact of ADHD impairment in the early morning and late afternoon/evening hours for adolescents and young adults.
- Trial name
- NCT04473755
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida International University
Autism Spectrum Disorder
Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype…
- Trial name
- NCT05013164
- Testing
- Folinic Acid
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Neurofibromatosis Type 1 (NF1), NF2-related Schwannomatosis
How Can the Experience of Hospital Outpatient Departments be Improved?
This project aims to improve outpatient departments by working with patients and staff to make these spaces more inclusive for people with sensory challenges (it focuses on people with nerve tumour conditions as they are more…
- Trial name
- NCT07818213
- Testing
- Qualitative data collection activities
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Attention Deficit Disorder With Hyperactivity
Screening for Attention-deficit/Hyperactivity Disorder (ADHD) in Adolescent and Adult High Risk Populations
This study aims to investigate the prevalence of ADHD and other psychopathology, and current function and life quality among several high risk populations of imprisoned adults and adolescents who receive special resources in…
- Trial name
- NCT00745524
- Where
- 2 sites in Taiwan
- Volunteers
- 1,910 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
The Effect of Hepatic Impairment on the Pharmacokinetics of Balovaptan
This is a multi-center, non-randomized, open-label, parallel group, multiple-dose study to assess the pharmacokinetic, safety, and tolerability of balovaptan in male and female subjects with moderate hepatic impairment compared…
- Trial name
- NCT03912350
- Testing
- Balovaptan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Refractive Error, Visual Impairment
The Baltimore Reading and Eye Disease Study
The Baltimore Reading and Eye Disease Study (BREDS) is a two year study to determine the prevalence of vision problems in an early school age population with reading difficulty.
- Conditions
- Refractive Error, Visual Impairment, Convergence Insufficiency, Reading Disabilities
- Trial name
- BREDS (NCT02607384)
- Testing
- Eyeglass wearing, Orthoptic exercises, Specialist referral
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Schizoaffective Disorder, Bipolar Type, Bipolar Disorder
Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues
Psychoneuromentalism Disorder is a disorder arising in the mind; that is related to the mental and emotional state of a person. It is the science of mental life. The body has a natural design to heal itself.
- Conditions
- Schizoaffective Disorder, Bipolar Type, Bipolar Disorder, ADHD - Combined Type, Dissociative Disorder
- Trial name
- PNMD (NCT06235177)
- Testing
- Decompartmentalization Framework, Liquid Herbal TInctures, Mental Imagery
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Essence of Integrative Health and Medicine Practice
Asphyxia
BRAIN - Home Intervention Trial
We plan to test a home-based parent-provided early developmental intervention (EI) both in infants with mild to moderate birth asphyxia and in infants without perinatal complications who will constitute a healthy comparison group…
- Trial name
- BRAIN-HIT (NCT00639184)
- Testing
- Early intervention counseling, Health education counseling
- Where
- 3 sites in India, Pakistan and 1 more
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Dyslexia, Developmental, Reading
Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation
This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning.
- Conditions
- Dyslexia, Developmental, Reading, Dyslexia, Learning
- Trial name
- LexiStim (NCT07546292)
- Testing
- Transcranial random noise stimulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Silvia Brem
Vision Impairment, Hearing Impairment
Health Intervention for Adolescents With Intellectual Disability
People with intellectual disability die five to twenty years earlier than the general population. They also experience high levels of unrecognised disease and receive inadequate levels of health promotion or screening.
- Conditions
- Vision Impairment, Hearing Impairment, Obesity
- Trial name
- Ask (NCT00519311)
- Testing
- Health Intervention Package
- Where
- Australia
- Volunteers
- 732 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Healthy
Effectiveness of the Serious Game 'Broodles' for Siblings of Children With Visual Impairment and/or Intellectual Disability
The support for siblings of children with disabilities is scarce and fragmented, even though studies have shown that these siblings can benefit from support.
- Trial name
- NCT05376007
- Testing
- Serious game 'Broodles'
- Where
- Netherlands
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Attention Deficit Disorder with Hyperactivity, Attention Deficit Hyperactivity Disorder
Effects of Exercise Intensity on ADHD Symptoms
This project investigates the effects of a bicycling exercise at three levels of exercise intensity (low, moderate, and high) on attention deficit/hyperactivity disorder (ADHD) in college students.
- Conditions
- Attention Deficit Disorder with Hyperactivity, Attention Deficit Hyperactivity Disorder, ADHD
- Trial name
- NCT06753253
- Testing
- Cycling Exercise
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kent State University
Developmental Language Disorder, Speech Sound Disorder
A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers
This broad aim of this clinical study is to assess the hypothesis that morphological and phonological deficits are linked by a broader deficit in sequential pattern learning.
- Conditions
- Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
- Trial name
- NCT04531514
- Testing
- Sensitivity to phonological rules & referents OR: Toddlers, Sensitivity to phonological rules & referents FR: Toddlers
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Cerebral Palsy
ePrime: Evaluation of Magnetic Resonance (MR) Imaging to Predict Neurodevelopmental Impairment in Preterm Infants
Preterm infants face an uncertain future because premature birth often leads to problems with brain development and can cause cerebral palsy.
- Trial name
- ePrime (NCT01049594)
- Where
- 13 sites in United Kingdom
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Autism Spectrum Disorder, Traumatic Brain Injury
Using Virtual Reality and Robotics Technologies for Vocational Evaluation, Training and Placement
Using Virtual Reality and Robotics Technologies for Vocational Evaluation, Training and Placement (VR4VR) is a project that incorporates Virtual Reality into job training to increase job opportunities for people who have physical…
- Trial name
- VR4VR (NCT02498262)
- Testing
- Virtual Reality System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Language Disorders in Children
Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties
In the proposed project, the investigators will conduct a multisite randomized controlled trial (RCT) to determine the efficacy of Let's Know!2, a small-group, language focused comprehension intervention, on children's lower- and…
- Trial name
- LK!2 (NCT05133479)
- Testing
- Let's Know! small-group or TierL 2 Intervention
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Autism Spectrum Disorder (ASD), Joint Attention Impairment
Social Attention in ASD and TD Children
To examine whether the spatiotemporal organization of gaze strategies differs between children with autism spectrum disorder (ASD) and typically developing (TD) children during a staged joint attention interaction, and to…
- Trial name
- NCT07583615
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center