Clinical trials: Neurogenic Inflammation
Neurogenic Inflammation, Dental Pulp Disease
Neuropeptide Y Regulates Neurogenic Pulp Inflammation
Objective. This study assessed the neuropeptide Y (NPY) expression in healthy human dental pulp following tooth bleaching with three in-office hydrogen peroxide-based systems: Opalescence Boost© (Ultradent Products, South Jordan…
- Trial name
- NCT06606236
- Testing
- H2O2 at 35% for 8 minutes, H2O2 at 40% for 20 minutes, H2O2 at 25% plus cold blue light for 15 minutes
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Occlusal Trauma, Orthodontic Appliance Complication
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response
This study measures SP, CGRP and VEGF expression in human dental pulp under occlusal trauma induced by occlusal interferences under moderate orthodontic forces or under a combination of occlusal trauma and moderate orthodontic…
- Trial name
- NCT03804034
- Testing
- Block of resin, Buccal tube, Bracket and 0.0017 × 0.025 in titanium molybdenum alloy wire
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Neurogenic Inflammation, Periimplant Diseases
Neurogenic Inflammation in Peri-implant and Periodontal Diseases
Regulatory effects of some neuropeptides substance-P (SP), neurokinin-A (NKA), calcitonin gene-linked peptide (CGRP) and neuropeptide-Y (NPY) )on inflammatory responses in periodontal disease has been described; however, the…
- Conditions
- Neurogenic Inflammation, Periimplant Diseases, Periodontal Diseases, Gingival Crevicular Fluid
- Trial name
- NCT03663140
- Testing
- gingival crevicular fluid (GCF) and peri-implant sulcular fluid(PISF) collection
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Fibromyalgia
Dynamic Contrast Enhanced (DCE)-MRI in Fibromyalgia
The primary objective of the current pilot study is to analyze MRI contrast-enhancement patterns in the hands of patients with fibromyalgia as compared to the findings in healthy controls.
- Trial name
- NCT01506817
- Testing
- Dynamic contrast-enhanced MRI of the hands
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Frederiksberg University Hospital