Clinical trials: Neurologic Complication
Sarcopenia, Postoperative Complications
Sarcopenia in Colorectal Cancer Patients, Intervention Study
The sarcopenia is a new concept for evaluating the functional status of patients, introduced during the last 20 years. This is defined as the relationship between the deterioration of muscle mass and the decrease in strength, the…
- Conditions
- Sarcopenia, Postoperative Complications, Infection;Post Surg Procedure
- Trial name
- NCT05491434
- Testing
- Protein supplement
- Where
- Spain
- Volunteers
- 370 people
- Sponsor
- Hospital Universitari de Bellvitge
Pain, Postoperative
Effect of Adding Hyaluronidase to Bupivacaine in Transversus Abdominis Plane Block for Cesarean Section
Since TAP block needs to affect several nerves in single tissue plane with a single prick, hyaluronidase is expected to aid greatly in the spread of the LA and help the block.
- Trial name
- NCT05671172
- Testing
- Hyaluronidase, Bupivacaine Injection
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Benha University
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Surgical Field, Acute Postoperative Pain
Bupivacaine 0.125% Versus Bupivacaine 0.25% in Superficial Cervical Plexus Block for Tympanomastoid Surgeries in Adults
Bleeding is one of the most common complications in tympanomastoid surgery that could prolong the time of operation and also might lead to morbidity.
- Trial name
- NCT06381401
- Testing
- bupivacaine 0.25%, bupivacaine 0.125%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Systemic Disease, Skin Diseases
Nutraceuticals and Functional Foods
Supplements and functional foods are now readily available and usable by the general population. Many supplemnets are commonly used in poly-treated patients where interactions or adverse events may develop, therefore we evaluate…
- Conditions
- Systemic Disease, Skin Diseases, Memory Disorders, Urologic Diseases
- Trial name
- NCT05509075
- Testing
- nutraceuticals
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Catanzaro
Cesarean Section, Pain, Postoperative
Use of Virtual Reality Glasses for Pain and Anxiety After Cesarean
The goal of this randomized controlled trial is to examine the effect of preoperative virtual reality used before cesarean on postoperative pain and anxiety.
- Conditions
- Cesarean Section, Pain, Postoperative, Anxiety
- Trial name
- NCT06232057
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Amasya University
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Endometriosis-related Pain, Endometriosis
Pelvic Neuro-Angiogenesis in Deep Endometriosis
Endometriosis is observed in one out of every ten women in society, causing endometrial cells to be found outside their normal location in the body and proliferate in other locations, leading to fibrosis in the tissue due to the…
- Conditions
- Endometriosis-related Pain, Endometriosis, Deep Endometriosis, Endometriosis; Peritoneum
- Trial name
- NCT06286371
- Testing
- Laparoscopic Endometriosis Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Uludag University
Post Operative Pain
A Study to Verify the Efficacy of YM177 (Celecoxib) in Postoperative Pain Patients
Aim of the study is to compare efficacy and safety of YM177 with placebo and etodolac in patients with postoperative pain.
- Trial name
- NCT01118572
- Testing
- YM177, etodolac
- Where
- 8 sites in Japan
- Volunteers
- 616 people
- Sponsor
- Astellas Pharma Inc
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Pain, Postoperative
Gastrectomy at Low Pressure Trial - (GALPT)
The study is designed to compare two different insufflation devices during surgery, CONMED AirSeal to Lexicon, during Laparoscopic Sleeve Gastrectomy.
- Trial name
- GALPT (NCT07313930)
- Testing
- AirSeal® Insufflation System (AIS), Lexicon AP 50/30 Insufflator
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- SurgiQuest, Inc.
Postoperative Pain, Midline Laparotomy
Analgesic Outcomes of Ultrasound-Guided QLB vs TAP Block in Midline Laparotomy
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults…
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Trial name
- NCT07796828
- Testing
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block, Bupivacaine 0.25%
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Sheikh Zayed Medical College
Pain, Postoperative, Endodontically Treated Teeth
Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation
The objective of this double-blind, randomized controlled clinical study will be to evaluate the effect f PBM on pain after endodontic instrumentation in the single-session treatment of upper molars and premolars.
- Trial name
- NCT06253767
- Testing
- Endodontic Treatment, Low Level Laser Therapy, Simulation Low Level Laser therapy
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Inguinal Hernia, Femoral Hernia
Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations
The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia…
- Conditions
- Inguinal Hernia, Femoral Hernia, Umbilical Hernia, Ventral Hernia
- Trial name
- NCT05920200
- Testing
- open non-mesh hernia repair, open mesh hernia repair, MIS hernia repair
- Where
- Russia
- Volunteers
- 4,000 people
- Sponsor
- Immanuel Kant Baltic Federal University
Chemotherapeutic Agent Toxicity, Neuropathy
Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer
This randomized phase III trial is studying glutathione to see how well it works in preventing peripheral neuropathy caused by paclitaxel and carboplatin in patients with ovarian cancer, fallopian tube cancer, and/or primary…
- Conditions
- Chemotherapeutic Agent Toxicity, Neuropathy, Neurotoxicity Syndrome, Pain
- Trial name
- NCT02311907
- Testing
- Carboplatin, Glutathione, Laboratory Biomarker Analysis
- Where
- 390 sites in United States
- Volunteers
- 195 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Postoperative Pain
Effect of Postoperative Single Dose of Ketamine on Pain After Mastectomy
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6mg/kg) of ketamine versus placebo (saline) on postoperative pain on adult women undergoing mastectomy.
- Trial name
- NCT04831736
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Postoperative Cognitive Dysfunction, Cognitive Impairment
Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2)
Patients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive…
- Conditions
- Postoperative Cognitive Dysfunction, Cognitive Impairment, Mild Cognitive Impairment, Delirium
- Trial name
- NCT03147937
- Testing
- Cognitive Testing
- Where
- Canada
- Volunteers
- 505 people
- Sponsor
- Dr. Stephen Choi
Colonic Neoplasms, Pain, Postoperative
The Effect of Methods of Self-regulation of Mental State on Pain Perception in the Postoperative Period in Colon Cancer Patients
In this study, it will be investigated whether the methods of self-regulation of mental state have an effect on postoperative pain perception in colon cancer patients.
- Conditions
- Colonic Neoplasms, Pain, Postoperative, Hypnotherapy
- Trial name
- NCT05708872
- Testing
- Autohypnosis, Relaxing music
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Pain, Postoperative
Assessment of Postoperative Pain in Children With Facial Expression Analysis
The present study was conducted to evaluate the use of computer-aided facial expression analysis to assess postoperative pain in children.
- Trial name
- NCT05345275
- Testing
- The facial expressions analyzed
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Uludag University
Pain, Postoperative
Block and Periarticular Injection Study
The purpose of the study is to compare two types of perioperative analgesic modalities, adductor canal block plus interspace between popliteal artery and capsule of the knee (IPACK) block and periarticular injection versus…
- Trial name
- NCT06410612
- Testing
- regional anesthesia and PAI, PAI
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Washington University School of Medicine
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