Clinical trials: Neurologic Complication
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Altius Peripheral Nerve Stimulation in Amputees After TMR/RPNI
This is a single-center, prospective, within-subject study. This study seeks to enroll a total of 32 prospective subjects who will undergo surgical implantation of the FDA-approved Altius® system.
- Trial name
- NCT07571239
- Testing
- Surgical Implantation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Postoperative Pain
Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Laparoscopic Surgeries
Postoperative pain after laparoscopic abdominal surgeries can be severe. Despite multimodal analgesia protocols, administration of high doses of opioids is often required hindering early mobilization and discharge of the patient…
- Trial name
- NCT05297981
- Testing
- Erector spinae plane block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain
A Multicenter Study: Dexmedetomidine Combined With Sufentanil for Patient Controlled Intravenous Analgesia After Caesarean Section
The purpose of this multicenter study is to evaluate the effectiveness and safety of dexmedetomidine combined with sufentanil for patient-controlled analgesia after caesarean section
- Trial name
- NCT02741219
- Testing
- Normal saline, Dexmedetomidine, Sufentanil
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Rotator Cuff Injury
Interscalene Brachial Plexus Block Combined With Suprascapular Nerve Block
The investigators compared the results of sono-guided interscalene brachial plexus block (ISB) combined with arthroscopy-guided suprascapular nerve block (SSNB) with those of ISB alone within the first 48 h after arthroscopic…
- Trial name
- NCT02424630
- Testing
- Ultrasound-guided ISB, Arthroscopy-guided SSNB, Ropivacaine
- Volunteers
- 52 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Tonsillitis, Postoperative Pain
Does Ice Cream Help With Post-tonsillectomy Pain
Tonsillectomy is one of the most performed procedures in childhood, which carries with it certain postoperative problems, such as the pain of the operated area.
- Conditions
- Tonsillitis, Postoperative Pain, Cryotherapy Effect
- Trial name
- NCT04164511
- Testing
- 2 daily standard doses of vanilla-chocolate ice cream (cryotherapy)
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Sestre Milosrdnice
Postoperative Pain
Pediatric Postoperative Pain Management in Surgical Wards - an Intervention Study
This study will explore healthcare providers' pediatric postoperative pain management knowledge and clinical practice. The aim of this study is to explore healthcare providers' knowledge and clinical practice in pediatric…
- Trial name
- NCT03987399
- Testing
- Tailored educational intervention
- Where
- Norway
- Volunteers
- 650 people
- Sponsor
- Oslo University Hospital
Endometriosis, Physical Inactivity
Chronic Pelvic Pain in Endometriosis
Endometriosis is a chronic, inflammatory disease affecting 10% (1 out of 10) of women of reproductive age. Pelvic pain is common among women with endometriosis.
- Conditions
- Endometriosis, Physical Inactivity, Chronic Pelvic Pain Syndrome, Quality of Life
- Trial name
- NCT05863663
- Testing
- questionnaire
- Where
- Hungary
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Pain, Complication of Injection
A Comparison of Injection Pain of Propofol During Endoscopy : LCT Propofol vs MCT/LCT Propofol
The purpose of this study is to compare the incidence and intensity of possible pain on injection as well as patient satisfaction caused by long chain triglyceride propofol versus medium/long chain combinated triglyceride…
- Trial name
- NCT02567916
- Testing
- Fresofol, Propofol
- Where
- South Korea
- Volunteers
- 129 people
- Sponsor
- Kyungpook National University Hospital
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Shoulder Arthroscopy, Interscalene Brachial Plexus Block
Shoulder Anterior Capsular Block and Interscalene Brachial Plexus Block for Shoulder Arthroscopy
The aim of our study is to reveal a comparison between interscalene brachial plexus block and shoulder anterior capsular block with respect to their efficacy on pain relief during perioperative anesthetic management.
- Conditions
- Shoulder Arthroscopy, Interscalene Brachial Plexus Block, Shoulder Anterior Capsular Block, Rotator Cuff Rupture
- Trial name
- NCT05727345
- Testing
- Interscalene brachial plexus block, Shoulder anterior capsular block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Haseki Training and Research Hospital
Pain, Postoperative, Catheter Blockage
Comparison of Catheters Orifice Configuration For Continuous Infraclavicular Analgesia
Infraclavicular nerve catheter for postoperative analgesia will be included in the 70 adult patients undergoing upper extremity surgery included in the study.
- Conditions
- Pain, Postoperative, Catheter Blockage, Anesthesia
- Trial name
- NCT04205695
- Testing
- CEMP (closed-ended multiport catheter) group, OESP (open-ended single port catheter) group, Patient-controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gulhane School of Medicine
Post Operative Pain, Spinal Surgery
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
The investigators propose a randomized, triple-blinded (patients, investigators, outcomes assessors), placebo-controlled pilot feasibility trial (Methadone to End Narcotic Dependence, MEND trial) to assess the feasibility and…
- Trial name
- MEND (NCT07222072)
- Testing
- Methadone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pain, Postoperative, Anxiety Preoperative
The Efficacy of a Mindfulness-Based Virtual Reality Intervention to Reduce Pain in Postoperative Patients
The goal of this randomized clinical trial is to evaluate whether a virtual reality (VR) mindfulness intervention can reduce anxiety and postoperative pain in adults undergoing surgery, primarily hernia and varicose vein…
- Trial name
- VR-MindPain (NCT06961695)
- Testing
- VR Mindfulness-Based Relaxation
- Volunteers
- 64 people
- Sponsor
- Babes-Bolyai University
Pain, Postoperative, Nerve Block
Use of Perioperative Pain Blocks In Urological Surgery
The study team aims to prospectively compare Placebo (local administration), ultrasound-guided transversus abdominis plane (UTAP) blocks, and laparoscopic-guided transversus abdominis plane (LTAP) blocks in patients undergoing…
- Conditions
- Pain, Postoperative, Nerve Block, Robotic Surgical Procedures
- Trial name
- NCT04426500
- Testing
- Bupivacain, Ultrasound-guided transversus abdominus plane block, Laparoscopic-guided transversus abdominus plane block
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain After Total Knee Arthroplasty, Pain, Postoperative
Comparison of BiFeS + ACB and IPACK + ACB Block Combinations for Postoperative Pain After Total Knee Arthroplasty
This prospective observational study will compare the postoperative analgesic efficacy of two multimodal regional anesthesia combinations routinely used after total knee arthroplasty (TKA) performed under spinal anesthesia.
- Conditions
- Pain After Total Knee Arthroplasty, Pain, Postoperative, Arthroplasty, Replacement, Knee
- Trial name
- NCT07231692
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Cervical Cancer Screening, Cervical Cancer Screening Methods
Ameliorated Pap Tests and Cervical Cancer Screening Participation
The Pap test plays a crucial role in the early detection of cervical cancer. A pilot single-center randomized controlled trial applied the peak-end concept and added a non-painful step at the end of Pap smear screening, aimed to…
- Trial name
- NCT06968871
- Testing
- Modified Pap test
- Where
- 5 sites in Taiwan
- Volunteers
- 850 people
- Sponsor
- National Taiwan University Hospital
Diabetic Neuropathies
Trial to Assess the Efficacy and Safety of SPM 927 (200, 400, and 600mg/Day) in Subjects With Painful Distal Diabetic Neuropathy
This phase 3 trial is being conducted at approximately 80 sites in the United States (U.S.) to investigate whether lacosamide (SPM 927) at different doses reduces pain in subjects with diabetic neuropathy.
- Trial name
- NCT00135109
- Testing
- SPM 927
- Where
- United States
- Volunteers
- 654 people
- Sponsor
- UCB Pharma
Postoperative Pain
The Analgesic Effect of QLB II After Robotic Prostatectomy. (QLB II: Quadratus Lomborum Block II Type)
The analgesic effects of Quadratus Lomborum Block II type after robotic-assisted laparoscopic radical prostatectomy, will be assessed.
- Trial name
- QLBII (NCT03941899)
- Testing
- Levobupivacaine in QLB II
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Knee Arthropathy, Postoperative Pain
Optimization of a Fast-track Concept for Knee Joint Replacement
In an estimated 150,000 patients, a knee joint replacement is performed in Germany every year. The perioperative care of the patients aims at an optimal surgical technique, which leads to a high functionality in the joint, and…
- Conditions
- Knee Arthropathy, Postoperative Pain, Postoperative Complications
- Trial name
- KneeOptOut2 (NCT03920930)
- Testing
- Late local infiltration analgesia, Early local infiltration analgesia
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
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