Clinical trials: Neurologic Complication
Femoracetabular Impingement, Pain, Postoperative
Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy
The purpose of this study is to determine whether intraoperative (during surgery) morphine and clonidine hip injections are effective in postoperative pain management for patients undergoing hip arthroscopy.
- Trial name
- NCT02530151
- Testing
- Morphine with clonidine, Normal saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Phantom Limb Pain, Amputation, Traumatic
Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)
This is a two-site study that explores the effects of mirror therapy and transcranial Direct Current Stimulation (tDCS, Soterix ©) in a randomized factorial controlled trial in which patients will be assigned to one of four…
- Trial name
- NCT02487966
- Testing
- transcranial Direct Current Stimulation (tDCS): active (Soterix ©), Mirror Therapy: active
- Where
- 2 sites in United States, Brazil
- Volunteers
- 132 people
- Sponsor
- Spaulding Rehabilitation Hospital
Turner Syndrome, Renal Insufficiency, Chronic
Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq
The main purpose of this study is to establish an optimal monitoring regimen in NutropinAq treated children, using newly developed capillary blood spot IGF-1 measurement technology.
- Conditions
- Turner Syndrome, Renal Insufficiency, Chronic, Pituitary Diseases, Dwarfism
- Trial name
- OPTIMA (NCT00234533)
- Testing
- Somatropin (rDNA origin)
- Where
- 45 sites in Belgium, Czechia and 12 more
- Volunteers
- 251 people
- Sponsor
- Ipsen
Lumbar Spine Surgery, Chronic Low-back Pain
Telehealth Mindfulness After Spine Surgery
The goal of this pilot clinical trial is to compare two behavioral interventions for patients who are recovering from lumbar spinal surgery for a degenerative spine condition. The study aims to answer the following questions: 1.
- Conditions
- Lumbar Spine Surgery, Chronic Low-back Pain, Postsurgical Pain
- Trial name
- NCT05698914
- Testing
- Telehealth mindfulness-based intervention (MBI), Telehealth Education
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Spinal Cord Injury, Neurogenic Bladder
Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation
The purpose of this study is to determine the efficacy of home transcutaneous tibial nerve stimulation (TTNS) in spinal cord injury(SCI) and to determine the impact on quality of life using TTNS at home
- Trial name
- TTNS-RCT (NCT04074616)
- Testing
- High Dose, Low dose
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea
The Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation
The investigators aim to investigate the effect of dexmedetomidine on the perioperative respiratory complications in this patient population undergoing both awake and deep tracheal extubation.
- Conditions
- Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Tonsillitis, Adenoiditis
- Trial name
- NCT02162433
- Testing
- Normal Saline, Dexmedetomidine
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Failed Back Surgery Syndrome, Back Pain
Spinal Cord Stimulation for Predominant Low Back Pain
The purpose of this study is to compare the effectiveness of spinal cord stimulation (SCS) using the Medtronic Specify® 5-6-5 multicolumn surgical lead plus optimal medical management (OMM) versus OMM alone in patients suffering…
- Conditions
- Failed Back Surgery Syndrome, Back Pain, Pain in Leg, Unspecified
- Trial name
- PROMISE (NCT01697358)
- Testing
- Spinal Cord Stimulation (SCS), Optimal Medical Management (OMM)
- Where
- 28 sites in United States, Belgium and 7 more
- Volunteers
- 278 people
- Sponsor
- MedtronicNeuro
Postoperative Pain
Dose Finding Posterolateral Thoracotomy Study
To review safety and effectiveness of two doses compared to current standard of care.
- Trial name
- NCT00807209
- Testing
- Low Dose SKY0402, High Dose SKY0402, Fentanyl via PCA
- Where
- 5 sites in United States
- Volunteers
- 3 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain, Procedural, Pain, Postoperative
The Effect of Vibration and Cold on Pain and Anxiety Associated With Chest Tube Removal Following CABG
Removal of chest tubes after coronary artery bypass graft (CABG) surgery can cause severe pain and anxiety, which may negatively affect the recovery process.
- Conditions
- Pain, Procedural, Pain, Postoperative, Coronary Artery Bypass Surgery, Chest Tubes
- Trial name
- CABG (NCT06217263)
- Testing
- Vibration device, Vibration device&Cold application pack
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative
Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
This is a phase II, single centre, randomised, parallel-group, double-blind, three doses, placebo-controlled, exploratory efficacy and safety study.
- Trial name
- NCT03428230
- Testing
- 30 mg Paracetamol 3% (1 mL), 60 mg Paracetamol 3% (2 mL), 90 mg Paracetamol 3% (3 mL)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Sintetica SA
Inguinal Hernia
Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects Undergoing Inguinal Hernia Repair
The primary objective of this study was to determine the appropriate dose of SKY0402 for the management of postoperative pain following inguinal hernia repair.
- Trial name
- NCT01203644
- Testing
- SKY0402, Bupivacaine HCl
- Volunteers
- 76 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Kidney Cancer, Melanoma (Skin)
Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases
RATIONALE: Cryoablation kills cancer cells by freezing them. Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells.
- Conditions
- Kidney Cancer, Melanoma (Skin), Metastatic Cancer, Pain
- Trial name
- NCT00540969
- Testing
- cryosurgery, radiation therapy
- Where
- 7 sites in United States
- Volunteers
- 3 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pain, Postoperative
Pre-incision Versus Post-incision Local Anesthetic During Robotic Sacrocolpopexy
Obtaining Likest-pain scale score on postoperative day one after injection of local anesthetic into incision sites of a laparoscopic/robotic-assisted sacrocolpopexy
- Trial name
- CLAPPS (NCT04996251)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Neurogenic Detrusor Overactivity
A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor Overactivity
This study will evaluate the pharmacodynamics and pharmacokinetics of darifenacin liquid oral suspension in children, ages 2-15 years, with neurogenic detrusor overactivity.
- Trial name
- NCT00712322
- Testing
- Darifenacin
- Where
- 12 sites in United States, Colombia
- Volunteers
- 35 people
- Sponsor
- Warner Chilcott
Postoperative Pain Relief
Transdermal Nicotine and Melatonin Patches for Postoperative Pain Relief
Sixty female non-smoker patients, aged 18-50 years and ASA I and II undergoing elective laparoscopic cholecystectomy under general anesthesia were included in this randomized controlled double-blind study.
- Trial name
- NCT02747628
- Testing
- transdermal therapeutic system- nicotine., transdermal therapeutic system- melatonin.
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Hip Arthroplasty
Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement
Chronic pain in patients following total hip replacement seems to be a significant problem. Previous research has shown that more effective pain management in the early postoperative period may decrease the incidence of the…
- Trial name
- NCT00621530
- Testing
- ketorolac tromethamine opthalmic solution
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Wake Forest University
Restless Legs Syndrome, End-Stage Renal Disease
A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring Hemodialysis
This is a sleep laboratory study to evaluate the efficacy and safety of Rotigotine in subjects with Restless Legs Syndrome and End-Stage Renal Disease requiring hemodialysis.
- Trial name
- NCT01537042
- Testing
- Rotigotine
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 30 people
- Sponsor
- UCB BIOSCIENCES GmbH
Breast Cancer, Postoperative Pain
Comparison of Pre-op and Post-op Pectoralis Nerve Block
The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or after mastectomy.
- Conditions
- Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
- Trial name
- NCT03653988
- Testing
- PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Melinda Seering
Postoperative Pain, Acute
Pulsed Shortwave Therapy for Postoperative Analgesia
Pulsed shortwave (radiofrequency) therapy is a possible method of pain control involving the application of electromagnetic energy (also termed pulsed electromagnetic fields).
- Trial name
- NCT05796583
- Testing
- Active Pulsed Shortwave Treatment
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
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