Clinical trials: Neurologic Complications
Postoperative Pain
Pediatric Tonsillectomy Pain Reduction Study
Tonsillectomy is associated with a significant decrease quality of life in children secondary to pain, which is worsened with swallowing.
- Trial name
- NCT00678379
- Testing
- lidocaine (1%) + bupivacaine (0.5%), Normal saline, Lidocaine (1%) + Bupivacaine (0.5%) + Clonidine (25mcg)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Polycystic Kidney, Type 1 Autosomal Dominant Disease, Polycystic Kidney, Type 2 Autosomal Dominant Disease
Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease
Sirolimus (SIR) has lead to a reduction of overall kidney size, a decrease in cyst density and general tubular cell proliferation in animal models, and to a reduction of the increase in creatinine and blood urea nitrogen by 34…
- Trial name
- RAP (NCT02055079)
- Testing
- Sirolimus
- Where
- Austria
- Volunteers
- 68 people
- Sponsor
- Medical University of Vienna
Post Operative Pain
Different Concentrations of Sodium Hypochlorite Affecting Post-endodontic Pain
This is a randomized, prospective, double-blind, clinical trial to assess the effect of 3% and 6% sodium hypochlorite (NaOCl) as irrigant on postendodontic pain and rescue medication intake following single visit root canal…
- Trial name
- NaOCl (NCT05840679)
- Testing
- Irrigation Solution
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Delirium, Postoperative Complications
Postoperative Delirium: Brain Vulnerability and Recovery
In this study, we propose to use EEG and a brain imaging technique known as diffuse optical tomography (DOT) to study when people are in delirium and when they recovery.
- Trial name
- NCT03110185
- Testing
- EEG, fcDOT, fcMRI
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Washington University School of Medicine
Low Back Pain, Musculoskeletal Diseases
Study of the Effectiveness of Osteopathic Manipulative Treatment in Pregnant Women
The purpose of this study is to determine whether osteopathic manipulative treatment (OMT): decreases pain and improves physical functioning in women during the third trimester of pregnancy decreases complications during…
- Conditions
- Low Back Pain, Musculoskeletal Diseases, Pregnancy Complications
- Trial name
- NCT00298935
- Testing
- Osteopathic manipulative treatment (OMT)
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- University of North Texas Health Science Center
Cerebral Palsy, Prematurity
Study of Generalized Movements for Early Prediction of Cerebral Palsy
The purpose of this study is to assess the predictive value of generalized movements in preterm and term infants who are at risk for development of cerebral palsy.
- Trial name
- NCT00749008
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Charles R. Neal,
Postoperative Pain
Method Study: Bilateral TAP Block With 24 Hours Infusion
The purpose of this method study in healthy volunteers is to determine the extent of sensory block following Transversus Abdominis Plane (TAP) block with 24 hours infusion of ropivacaine versus infusion of saline.
- Trial name
- NCT01577940
- Testing
- Infusion of ropivacaine, Infusion of saline
- Where
- 2 sites in Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Apical Periodontitis
Comparison of AH Plus and WellRootST Root Canal Sealers in Terms of Postoperative Pain: One-Month Follow-up
This randomized, parallel-group clinical trial aimed to compare the effects of two root canal sealers, AH Plus and Well-Root ST, on postoperative pain in patients undergoing single-visit root canal treatment for teeth diagnosed…
- Trial name
- NCT07246174
- Testing
- AH Plus Root Canal Sealer, Well-Root ST Root Canal Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Medipol University
Postoperative Pain, Knee Surgery
Comparison of Nerve Blocks for Pain Relief After Knee Surgery
This retrospective observational study compares the postoperative analgesic effectiveness of ultrasound-guided fascia iliaca compartment block (FICB) with combined IPACK and genicular nerve block (GNB) in patients undergoing knee…
- Trial name
- NCT07845591
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block, Ultrasound-Guided Combined IPACK and Genicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Gaziantep
Postoperative Pain
Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy
The purpose of this study is to prospectively determine the influence of immediate pre-operative gabapentin administration on acute postoperative pain.
- Trial name
- Gabapentin (NCT02359110)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cholelithiasis
Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes
This randomized controlled trial aims to evaluate the effects of video-assisted early mobilization education on postoperative recovery in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT07512024
- Testing
- Video-Assisted Early Mobilization Training
- Volunteers
- 44 people
- Sponsor
- Muş Alparslan University
Postoperative Pain, Percutaneous Nephrolithotomy
The Effectiveness of Quadro İliac Plane Block in Percutaneous Nephrolithotomies
Our aim was to investigate the effect of quadro iliac plane block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy surgery and to determine which areas of the skin this block anesthetizes.
- Trial name
- NCT07203859
- Testing
- Quadro-İliac Plane Block(QİPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Failed Back Surgery Syndrome
Improvement of Gait by Spinal Stimulation in Patients With Postoperative Chronic Lumbosciatalgia: Pilot Study (GaitStim)
The purpose of this study is to explore the changes in objective walking parameters induced by medullary stimulation in patients with Fail Back Surgery Syndrome, after chronic stimulation, in comparison with preoperative…
- Trial name
- GAITSTIM (NCT05857696)
- Testing
- walking quantified analysis
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain, Postoperative, Thoracic Diseases
Liposomal Bupivacaine for Pain Control Following Thoracic Surgery.
The aims of the study are to compare the effectiveness and postoperative outcomes of liposomal bupivacaine vs plain bupivacaine following video-assisted thoracoscopic surgery.
- Conditions
- Pain, Postoperative, Thoracic Diseases, Local Anesthetics Causing Adverse Effects in Therapeutic Use, Opioid Dependence
- Trial name
- NCT03036085
- Testing
- Liposomal bupivacaine, Bupivacaine, Epinephrine
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Pain, Postoperative
Heart Rate Variability and Postoperative Pain
Postoperative pain stimulates the autonomic nervous system, induces the production of pro-inflammatory substances, reduces patient mobility and impairs vital functions.
- Trial name
- ECG-Spectral (NCT00438035)
- Testing
- ECG spectral
- Where
- France
- Volunteers
- 106 people
- Sponsor
- University Hospital, Bordeaux
Emergence Delirium
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children
Postoperative agitation and emergence delirium describe a spectrum of symptoms of early postoperative negative behavior, in which the child experiences a variety of behavioral disturbances including crying, thrashing, and…
- Trial name
- MELA-PAED (NCT05541276)
- Testing
- Melatonin, Isotonic sodium chloride solution
- Where
- Denmark
- Volunteers
- 676 people
- Sponsor
- Arash Afshari
Neurogenic Bladder
Effect of Electroacupuncture at Different Acupoints on Bladder Function After Spinal Cord Injury
Neurogenic bladder after spinal cord injury can be divided into detrusor hyperreflexia and detrusor non reflexia. Acupuncture is recognized as a safe and effective treatment.
- Trial name
- NCT05262816
- Testing
- electroacupuncture
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Low Back Pain, Physical Inactivity
The Association Between Urinary Incontinence, Physical Performance, Physical Activity Levels in Women With Low Back Pain
The study is searching for the correlation between low back pain(LBP), physical performance, urinary incontinence and physical activity levels in women.
- Conditions
- Low Back Pain, Physical Inactivity, Urinary Incontinence
- Trial name
- NCT05339516
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pinar Yasar
Analgesia, Postoperative Pain Management
ESP Block for Postoperative Analgesia in URS Surgery
The goal of this clinical trial is to determine whether the erector spinae plane (ESP) block provides better pain relief after flexible ureterorenoscopy (URS) surgery compared to standard analgesia alone.
- Conditions
- Analgesia, Postoperative Pain Management, Nephrolithiasis
- Trial name
- ESPURS (NCT06826833)
- Testing
- Erector Spinae Plane (ESP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Namik Kemal University
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