Clinical trials: Neurologic Complications
Emergence Delirium, Postoperative Pain
Effect Study of Parecoxib to Treat Emergence Delirium and Postoperative Pain
This prospective, double blind, placebo-controlled, parallel group study will be conducted in three study centers in Guangzhou, China.
- Trial name
- NCT01221025
- Testing
- Parecoxib
- Where
- China
- Volunteers
- 900 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Catheter Complications
Port Catheter Needle Insert: A Virtual Reality Application
The study was randomized controlled to examine the effect of virtual reality (VR) application on pain, anxiety, and vital signs associated with port catheter needle insertion.
- Trial name
- NCT05950789
- Testing
- Virtual reality application
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Izmir Bakircay University
Pain Management, Pain, Postoperative
Preperitoneal Analgesia Versus Epidural Analgesia After Open Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares thoracic epidural analgesia and continuous preperitoneal analgesia after open pancreaticoduodenectomy.
- Trial name
- Pain (NCT04375826)
- Testing
- Epidural patient controlled analgesia, Preperitoneal analgesia and IV-PCA
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Seoul National University Hospital
Premature Infant, Developmental Delay
A Parent Administered Sensorimotor Intervention and Developmental Outcome of Preterm Infants
Advances in medical technologies over the last three decades have increased survival rates in infants born preterm . Preterm infants are at high risk of developing developmental delays.
- Trial name
- NCT03836326
- Testing
- Sensorimotor intervention, Control, Story telling attention refocusing intervention
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Dr. Sandra Fucile
Postpartum Depression, Sleep Disorder
The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression
It is recommended by the American College of Obstetricians and Gynecologists' Committee on Obstetric Practice that all obstetricians screen each women for postpartum depression and anxiety with a validated instrument.
- Conditions
- Postpartum Depression, Sleep Disorder, Breast Feeding, Self Esteem
- Trial name
- NCT03763435
- Testing
- Antenatal pregnancy classes
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Bartin State Hospital
Herpes Zoster, Neuralgia
NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is determine if an investigational drug, NGX-4010 (high-concentration capsaicin dermal patches) is effective in treating pain associated with post-herpetic neuralgia (PHN).
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00061776
- Testing
- Capsaicin Dermal Patch
- Where
- 28 sites in United States
- Volunteers
- 300 people
- Sponsor
- NeurogesX
Pain, Chronic, Failed Back Surgery Syndrome
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain.
- Trial name
- NCT03718325
- Testing
- Burst-SCS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Apical Periodontitis
Apical Patency, Periapical Lesion Volume, and Postoperative Pain After Root Canal Treatment
This prospective clinical study evaluated whether maintaining apical patency during single-visit root canal treatment influences postoperative pain in adults with single-rooted maxillary anterior teeth and chronic apical…
- Trial name
- NCT07782515
- Testing
- Apical Patency During Root Canal Treatment, Root Canal Treatment Without Apical Patency
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Recep Tayyip Erdogan University
Brain Tumor, Central Nervous System Tumor
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
RATIONALE: Sodium thiosulfate may reduce or prevent hearing loss in young patients receiving cisplatin for cancer. It is not yet known whether sodium thiosulfate is more effective than no additional treatment in preventing…
- Conditions
- Brain Tumor, Central Nervous System Tumor, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
- Trial name
- NCT00716976
- Testing
- sodium thiosulfate, examination
- Where
- 76 sites in United States, Australia and 1 more
- Volunteers
- 131 people
- Sponsor
- Children's Oncology Group
Trisomy 13, Trisomy 18
Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial
This prospective blinded study will assess the diagnostic capability of an informatics enhanced SNP based technology (Parental Support) to identify pregnant women who are carrying a fetus with an aneuploidy from fee floating DNA…
- Conditions
- Trisomy 13, Trisomy 18, Trisomy 21, Aneuploidy
- Trial name
- PreNATUS (NCT01545674)
- Testing
- Blood Draw
- Where
- 29 sites in United States, Canada and 4 more
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Neurological Complication
The Influence of Neuromuscular Reversal on Neurological Physical Exam Time in Lumbar Neurosurgical Cases.
Neurological physical exam is a very important outcome that should be evaluated as soon as possible after every lumbar procedures.
- Trial name
- NCT03399890
- Testing
- Neurological physical exam
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Ankara University
Hyperprolactinemia, Endometriosis
Endometriosis Patients Undergoing Quinagolide Treatment
Dopamine agonists, such as quinagolide, are able to act on the VEGFR-2 blocking antibodies, diminishing Vascular Endothelial Growth Factor effect on angiogenesis in human endometriotic lesions.
- Trial name
- NCT00625950
- Testing
- ENDOMETRIAL BIOPSY
- Where
- Spain
- Volunteers
- 5 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Multiple Sclerosis (MS), Neurogenic Bladder Disorder
Essential Oils for Urinary Symptoms in Multiple Sclerosis Patients
The goal of this clinical trial is to learn if essential oil aromatherapy works to improve urinary symptoms in adults with multiple sclerosis. It will also learn about the safety of essential oil use in this population.
- Conditions
- Multiple Sclerosis (MS), Neurogenic Bladder Disorder, Urinary Incontinence (UI), Urinary Urgency
- Trial name
- AROMA-MS (NCT07599189)
- Testing
- Essential Oil Blend (Lavender, Rosemary), Neutral Carrier Oil (Apricot Kernel Oil)
- Where
- 2 sites in Algeria
- Volunteers
- 60 people
- Sponsor
- University of Oran 1
Delivery Problem, Childrearing
Perineal Massage Performed During the Labour
In this study, perineal massage was applied to primiparous women who did not give birth before, as a quasi-experimental control group to determine the effects of massage on birth comfort, perineal trauma and perineal pain.
- Conditions
- Delivery Problem, Childrearing, Satisfaction, Patient, Perineum; Injury
- Trial name
- NCT05962918
- Testing
- Perinal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Munzur University
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Acute Postoperative Pain After Cesarean Delivery
LI4 and SP6 Acupuncture for Pain After Cesarean Delivery
This randomized, sham-controlled clinical trial will evaluate the effectiveness of acupuncture at bilateral LI4 and SP6 as an adjunct to standard postoperative analgesia for acute pain after cesarean delivery.
- Trial name
- NCT07869589
- Testing
- Bilateral Acupuncture Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Nigde Omer Halisdemir University
Postoperative Pain, Postoperative Nausea
Postoperative Outcomes After Positive Intraoperative Messages
The patients scheduled for laparoscopic cholecystectomy will be allocated to 3 groups. Group A and B patients will listen to a positive message under general anesthesia. Group C patients will not listen to the message.
- Conditions
- Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT02765750
- Testing
- Intraoperative positive messages, No message
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- 424 General Military Hospital
Radical Prostatectomy, Postoperative Pain
Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic Prostatectomy
Prostate cancer is the commonest cancer form in men in Northern Europe. Management of the cancer often includes surgical removal of the primary tumor.
- Trial name
- RAPID (NCT03639389)
- Testing
- Bupivacaine, Analgesics
- Where
- 2 sites in Sweden
- Volunteers
- 211 people
- Sponsor
- Karolinska Institutet
Postoperative Pain, Breast Cancer
Analgesic Efficacy of Erector Spinae Plane Block After Breast Cancer Surgery
Erector spinae plane block(ESPB), which is firstly used for thoracic neuropathic pain, is newly developed and highly promising fascial plane block for providing postoperative analgesia for a great deal of surgeries including…
- Trial name
- NCT04512391
- Testing
- Ultrasound guided Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- TC Erciyes University
Failed Back Surgery Syndrome, Neuropathic Pain
The Pain Suppressive Effect of Alternative Spinal Cord Stimulation Frequencies
Electrical stimulation of the spinal cord (Spinal Cord Stimulation or SCS) for pain relief has been used for decades. It is used most commonly in patients with chronic neuropathic leg pain, after spinal surgery.
- Trial name
- HALO (NCT02112474)
- Testing
- Spinal Cord Stimulation, Group 1, Group 2
- Where
- 5 sites in Netherlands
- Volunteers
- 30 people
- Sponsor
- Jennifer Breel
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