Clinical trials: Neurologic Complications
Irritable Bowel Syndrome, Ulcerative Colitis
Efficacy of Gralise® for Chronic Pelvic Pain
This study is done to investigate the pain relieving effects of the study drug Gralise (a novel long acting gabapentinoid) for people who experience chronic pelvic pain.
- Conditions
- Irritable Bowel Syndrome, Ulcerative Colitis, Interstitial Cystitis, Prostatitis
- Trial name
- NCT01678911
- Testing
- Gralise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Shirley Ryan AbilityLab
Post Operative Pain
A Comparative Study Between Ultrasound Guided Erector Spinae Plane Block and Combined Ultrasound Guided Pericapsular Nerve Group and Lateral Femoral Nerve Block Following Total Hip Arthroplasty
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: patients will receive Pericapsular nerve group block and lateral femoral cutaneous nerve blocks.
- Trial name
- NCT06402006
- Testing
- PENG block, LFCN block, ESP block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Strabismus
Effect of Remifentanil on Postoperative Vomiting in Pediatric Strabismus Surgery
The purpose of this study is to compare the effect of remifentanil on postoperative vomiting in children undergoing strabismus surgery during sevoflurane anesthesia.
- Trial name
- NCT02455401
- Testing
- High dose remifentanil, Low dose remifentanil, No remifentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Inje University
Postoperative Pain
Bilateral Transversus Abdominis Plane Block and Postoperative Pain Intensity After Elective Cesarean Delivery
The patients planned to go under elective cesarean delivery under general anesthesia are randomly assigned to have either bilateral transversus abdominis plane (TAP) block or usual standard analgesics after cesarean.
- Trial name
- TAP (NCT00964600)
- Testing
- TAP blockade
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Premature Birth
Assessment of Autonomic Regulation During the Listening of Mother Heart Beat in Newborns
Prematurity birth lead to an early breaking link with the in utero environment. A special attention is brought in the neonatal intensive care units to reduce noise and lighting surrounding aiming to protect the newborn.
- Trial name
- Cardio_Sound (NCT04821011)
- Testing
- electronic stethoscope, acoustic listening of mother's heartbeats, Recording of the newborn's heart rate
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gastroparesis, Diabetes Complications
To Study the EGG Abnormalities in Healthy Subjects and in Patients With Idiopathic and Diabetic Gastroparesis.
Electrogastrogram (EGG) is a non-invasive method for recording myoelectric activities by placing electrodes on the abdomen surface.
- Conditions
- Gastroparesis, Diabetes Complications, Idiopathic Gastric Motility Disorder, Dyspepsia
- Trial name
- NCT05624034
- Testing
- Electrogastrography
- Where
- India
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Kidney Cancer, Leukemia
Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy
RATIONALE: Voriconazole may be effective in preventing systemic fungal infections following chemotherapy. PURPOSE: Phase II trial to study the effectiveness of voriconazole in preventing systemic fungal infections in children who…
- Conditions
- Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00066599
- Testing
- voriconazole
- Where
- 7 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Pain, Postoperative
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
Effective post surgical pain control in patients undergoing unilateral deep inferior epigastric perforator (DIEP) free flap reconstruction.
- Trial name
- NCT04284930
- Testing
- Depobupivacaine, OnQ pump, 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain
Postoperative Pain of Rotary Versus Reciprocating Motions of Two Single Files
An equivalent parallel randomized clinical trial was approved by the local University Committee of Ethics. 260 children with necrotic primary molars were allocated into 2 equal groups (82 children per group).
- Trial name
- NCT05059171
- Testing
- OneSahpe single file, WaveOne Gold single file
- Where
- Egypt
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Minia University
Postoperative Pain
Postoperative Analgesia Using Ganglion Impar Block After Anal Surgery
The aim of this study is to evaluate the ganglion Impar block in the prevention of postoperative pain after anal surgery.
- Trial name
- NCT04110132
- Testing
- Ganglion impar block with Bupivacaine., Ganglion impar block with normal saline
- Volunteers
- 60 people
- Sponsor
- University of Alexandria
Parkinson Disease
The Effect of Parkinson Kinetigraph Recordings on the Management and Outcome in Parkinson's Disease
With time most people with Parkinson's disease (PwP) develop fluctuations in motor symptoms in relation to medication intake. The prevalence may be both under and overestimated as it is based on history rather than observation.
- Trial name
- NCT03152721
- Testing
- Parkinson KinetiGraph, Self assessment
- Where
- Sweden
- Volunteers
- 147 people
- Sponsor
- Sahlgrenska University Hospital
Postoperative Pain, Pelvic Pain
Interfascial Abdominal Wall Block for Gynecological Laparoskopy: A Randomized Clinical Trial
The purpose of this study is to evaluate the clinical efficacy of combining ultrasound-guided bilateral rectus sheath blocks (RSB) and quadratus lumborum blocks (QLB) compared to using a quadratus lumborum block alone for…
- Trial name
- NCT07705516
- Testing
- Bilateral QLB and RSB, Bilateral QLB alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Medical and Diagnostic Center "MEDION" LLC
Acute Post Operative Pain, Postsurgical Pain Management
Intravenous Methocarbamol for Acute Pain After Spine Surgery
The goal of this target trial emulation is to evaluate the impact of intravenous (IV) methocarbamol on postoperative pain and opioid use in adults undergoing elective spine surgery.
- Conditions
- Acute Post Operative Pain, Postsurgical Pain Management, Spine Surgery, Acute Pain, Postoperative
- Trial name
- IMAPSS (NCT06659965)
- Testing
- Intravenous Methocarbamol
- Where
- United States
- Volunteers
- 1,270 people
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer, Lung Cancer
Pillars4Life Trial
This study aims to explore whether cancer patients can benefit from completing the Pillars4Life online coping program. This randomized control trial will have half its subject completing the program and the other half receiving…
- Conditions
- Breast Cancer, Lung Cancer, Esophageal Cancer, Colon Cancer
- Trial name
- Pillars4Life (NCT02465892)
- Testing
- Pillars4Life
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- Duke University
Postoperative Pain
Erector Spinae Plane Block for Postoperative Pain Control in Hip Replacement Surgeries
ESP block advantages include its simplicity, easy identifiable ultrasonographic landmarks and low risk for serious complications as injection is into tissue plane that is distant from pleura, major blood vessels and discrete…
- Trial name
- NCT04003909
- Testing
- ultrasound-guided Erector spinae plane block, subarachonoid block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Bassant M. Abdelhamid
Postoperative Pain
Transversus Abdominis Plane Block Versus Wound Infiltration for Pulmonary Function Preservation Following Laparoscopic Living Donor Nephrectomy
This study compares two pain control techniques in patients undergoing laparoscopic kidney donation surgery: transversus abdominis plane (TAP) block versus wound infiltration with local anesthetic.
- Trial name
- TAPWIN (NCT06837909)
- Testing
- Transversus abdominis plane (TAP) block, Wound infiltration
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Postoperative Nausea and Vomiting, Postoperative Pain
Dexamethasone Improves Postoperative Symptoms After Laparoscopic Cholecystectomy
Dexamethasone has been reported to reduce postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy (LC). However, its effects on other surgical outcomes such as pain and fatigue have been unclear.
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Postoperative Fatigue
- Trial name
- dxt (NCT01030614)
- Testing
- Dexamethasone
- Where
- Mexico
- Volunteers
- 210 people
- Sponsor
- Instituto Mexicano del Seguro Social
Covid19, Myocardial Infarction
Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales
This retrospective cohort study aims to characterise outcomes for patients treated on an intensive care unit (ICU) with COVID-19 in England and Wales, one year after discharge from hospital.
- Conditions
- Covid19, Myocardial Infarction, Stroke, Critical Illness
- Trial name
- OPTIC-19 (NCT04838106)
- Testing
- Not applicable as observational study
- Where
- United Kingdom
- Volunteers
- 319,600 people
- Sponsor
- University of Oxford
Pain
Fundal Block in Pre-menopausal Women to Reduce Pain During Outpatient-based Endometrial Ablation (FUNDAL-PAIN)
The objective of this study is to assess the efficacy of a fundal block in reducing women's perception of pain during NovaSure endometrial ablation (EA) in an outpatient-based setting.
- Trial name
- FUNDAL-PAIN (NCT04249063)
- Testing
- Xylocaine 1 % and Normal Saline, Normal Saline
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Phantom Limb Pain
Reliability and Validity of Outcome Measures for Phantom Limb Pain
Phantom limb pain (PLP) is experienced by 60-80% of all people who have had an amputation. This persistent pain condition can impact on independence, activities of daily living and overall quality of life.
- Trial name
- NCT03588793
- Testing
- Two Point Discrimination
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Teesside University
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