Clinical trials: Neurologic Findings
Sedation and Analgesia
Effect of Mild Sedation and Analgesia on Radial Artery Cannulation in Novice Residents
The aim of this study is to conduct a prospective, single-center randomized controlled study to investigate the effect of mild midazolam combined with sufentanil on radial artery cannulation in novice operators.
- Trial name
- NCT05863455
- Testing
- mild sedation and analgesia, control
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Intensive Care Patients
The Effect of Passive Music Therapy and Foot Massage
Patients hospitalized in tertiary intensive care units are connected to mechanical ventilators due to multiorgan failure, chronic diseases, respiratory failure, etc.
- Trial name
- NCT06078826
- Testing
- passive music therapy, foot massage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- TC Erciyes University
Pain
Efficacy and Safety of ALGRX 3268 in Children Undergoing Minor Needle-Stick Procedures.
Minor needlestick procedures often cause significant pain and distress in pediatric patients yet interventions to reduce pain are used infrequently.
- Trial name
- NCT00146185
- Testing
- ALGRX 3268
- Where
- United States
- Volunteers
- 504 people
- Sponsor
- AlgoRx Pharmaceuticals
Stroke
Brunnstrom Movement Therapy Versus Mirror Therapy on Hand Function in Stroke
This study will be randomized clinical trial. Non Probability consecutive sampling technique will be used. Data will be collected from patients having stroke by using tools i.e Fugl-Meyer assessment: wrist and hand (FMA- WH) and…
- Trial name
- NCT05392543
- Testing
- Brunnstrom movement therapy., Mirror Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Endodontically Treated Teeth, Post Operative Pain
The Effect of Instrumentation and Obturation on Postoperative Pain in Retreatment
Objectives: The aim of this study was to assess postoperative pain in prospective randomized clinical trial comparing Reciproc or hand instrument and also different obturation techniques in one visit of endodontic retreatment.
- Trial name
- NCT04789343
- Testing
- Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Trigeminal Neuralgia, Pain, Neuropathic
FMRI Assessment After Radiofrequency in Trigeminal Neuralgia
To investigate the brain activations related to TN, using fMRI, and to evaluate changes in these activations following the application of pulsed and thermal Radiofrequency lesioning to the gasserien ganglion.
- Trial name
- NCT03305289
- Testing
- pulsed Radiofrequency, thermal Radiofrequency
- Volunteers
- 20 people
- Sponsor
- Assiut University
Postoperative Delirium
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
This pilot cluster-randomised controlled trial aims to determine whether the use of bedside mirrors, as a clearly defined part of patients' postsurgical ICU care, can reduce delirium and improve outcomes in the older cardiac…
- Trial name
- NCT01599689
- Testing
- Mirrors Intervention
- Where
- United Kingdom
- Volunteers
- 223 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Pain, Postoperative, Anesthesia, Regional
Comparison of the Efficiency of PENG Block and ESP Block Used for Postoperative Analgesia in Elective Hip Surgery
The aim of the study is to determine whether the traditional intravenous analgesia technique or the ultrasound-guided pericapsular nerve group block or the unilateral erector spina plane block technique is superior in…
- Conditions
- Pain, Postoperative, Anesthesia, Regional, Hip Surgery, Ultrasound-Guided
- Trial name
- NCT05802589
- Testing
- Lumbar Erector Spinae Plane Block, Pericapsular Nerve Group Block, no peripheral block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Neck Pain
Effects of Kendall Exercises Versus Scapular Stabilization Exercises Oin Mechanical Neck Pain
Neck pain is a multifactorial disease, and is a major problem in modern society. Patients with NCNP usually have alterations in cervical proprioception and PS. They may also develop symptoms such as dizziness or vertigo.
- Trial name
- NCT07062991
- Testing
- Kendall Exercises, Scapular stabilization exercises
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Stomatitis, Pain
MucoLock™ for Treatment of Stomatitis
The purpose of this research is to test how well people can tolerate MucoLock™ as a treatment for mouth pain or burning sensation and how well it works to reduce mouth pain or burning sensation.
- Conditions
- Stomatitis, Pain, Burning Mouth, Burning Mouth Syndrome
- Trial name
- NCT07506018
- Testing
- MucoLock Oral Gel
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Baptist Health South Florida
Hypoxic Ischemic Brain Injury, Neonatal Encephalopathy
Dexmedetomidine Versus Morphine During Cooling Therapy in Neonates
About ~3/ 1000 live-born newborns may suffer from brain injury due to a transient drop in oxygen supply to the brain during the birth process.
- Conditions
- Hypoxic Ischemic Brain Injury, Neonatal Encephalopathy, Perinatal Anoxic-ischemic Brain Injury
- Trial name
- COOL-SED (NCT06985290)
- Testing
- Dexmedetomidine Infusion, Morphine Infusion
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ipsita Goswami
Osteo Arthritis Knee
Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty
An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.
- Trial name
- NCT03395990
- Testing
- Active comparator: chloroprocaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3
Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam
This Phase 3 trial (Study SRK-015-003) was conducted in patients ≥2 years old at Screening, who were previously diagnosed with later-onset spinal muscular atrophy (SMA) (i.e., Type 2 and Type 3 SMA) and were receiving an approved…
- Conditions
- Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type 2, SMA
- Trial name
- SAPPHIRE (NCT05156320)
- Testing
- Apitegromab
- Where
- 50 sites in United States, Belgium and 7 more
- Volunteers
- 188 people
- Sponsor
- Scholar Rock, Inc.
Pain Management, 3D Printing
The Effectiveness of the Three-dimensional Biochemical Activity Model of Pain
Aim: In this study, it was aimed to develop a pain biochemical activity model taken from a three-dimensional printer and fixed by applying epoxy resin and to investigate the effect of this model on nursing students' understanding…
- Conditions
- Pain Management, 3D Printing, Education Nursing
- Trial name
- NCT07389382
- Testing
- 3D printed pain biochemical activity training model, PowerPoint Presentations
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Multiple Sclerosis, Ataxia
Investigation of the Effects of Local Vibration Applied to Different Regions and Spinal Stabilization Exercises
The aim of this study is to investigate the effects of local vibration application applied to different regions on postural control in addition to spinal stabilization training in ataxic multiple sclerosis (MS) patients.
- Trial name
- NCT05885282
- Testing
- paraspinal vibration, gastrosoleus muscle complex vibration, Control Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Postoperative Sore Throat, Bronchoscopy
Dexmedetomidine Nasal Spray and Postoperative Sore Throat After Bronchoscopy
The goal of this observational study is to learn whether dexmedetomidine nasal spray is associated with a lower risk of postoperative sore throat in adult patients who underwent bronchoscopy under general anesthesia.
- Conditions
- Postoperative Sore Throat, Bronchoscopy, Hoarseness, Dysphagia
- Trial name
- NCT07894224
- Testing
- Dexmedetomidine Nasal Spray, standard general anesthesia
- Where
- China
- Volunteers
- 4,400 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Tardive Dyskinesia
A Phase 3 Study of NBI-98854 for the Treatment of Tardive Dyskinesia
The purpose of this study is to evaluate the efficacy, safety, and tolerability of NBI-98854 administered once daily for the treatment of Tardive Dyskinesia (TD) symptoms.
- Trial name
- KINECT 3 (NCT02274558)
- Testing
- NBI-98854
- Where
- 54 sites in United States, Canada and 1 more
- Volunteers
- 234 people
- Sponsor
- Neurocrine Biosciences
Lower Extremity Problem, Surgery
Ibuprofen IV vs Acetaminophen IV for the Treatment of Pain Following Orthopaedic Low Extremity Surgery
This study aims to evaluate the efficacy of IV Ibuprofen versus IV Acetaminophen in the reduction of pain following orthopedic low extremity procedures
- Conditions
- Lower Extremity Problem, Surgery, Postoperative Pain
- Trial name
- NCT03771755
- Testing
- Ibuprofen, Acetaminophen
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Universitas Indonesia
Angina Pectoris, Metabolic Syndrome X
Rosiglitazone Versus Placebo in Chronic Stable Angina
We wish to see if the drug rosiglitazone, currently used in the treatment of type 2 diabetes, could be used as a new treatment for angina when compared with placebo in overweight subjects who do not have overt diabetes.
- Trial name
- NCT00225355
- Testing
- Rosiglitazone
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Glasgow
Hearing Loss
Restoration of Spectral Resolution With Hearing-aid Amplification
The objective of this study protocol is to determine the efficacy of using aided measures of spectral resolution to set the dynamic range of hearing with hearing-aid amplification.
- Trial name
- NCT03850678
- Testing
- Hearing Aid
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.