Clinical trials: Neurologic Findings
Disabilities, Intellectual, Disability, Developmental
Appropriate Medication Use for Individuals With Intellectual Disabilities - A Matter of Life
The innovation idea is to develop valuable new knowledge about safe drug use in people with intellectual and/or developmental disabilities (IDDs).
- Trial name
- NCT06160102
- Testing
- Develop and implement the Framework for safe drug use in people with intellectual and/or developmental disabilities
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Vestvagoy Municipality
Spinocerebellar Degeneration
A 24-week Open-label Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)
The purpose of this study is to evaluate the safety, efficacy, and pharmacokinetics of KPS-0373 in SCD patients (Experience of clinical trials of KPS-0373)
- Trial name
- NCT01970137
- Testing
- KPS-0373, High dose, KPS-0373, Low dose
- Where
- Japan
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
SCI - Spinal Cord Injury, Spastic
"Validated Language Transfer of the Spinal Cord Injury-Spasticity Evaluation Tool to German Language"
To better depict the full range of spasticity after Spinal Cord Injury (SCI) there is a need to take into account the patients perspective and their experiences during daily life.
- Trial name
- SCI-SETde (NCT05022095)
- Testing
- Questionnaires
- Where
- Switzerland
- Volunteers
- 65 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Sleep Apnea, Obstructive
Postoperative Oral Cryotherapy in Sore Throat and Daily Life
The purpose of this study will to evaluate the degree of postoperative sore throat and Life Impairment changes in patients with sleep apnea who underwent da Vinci robotic arm surgery as an intervention of oral cryotherapy.
- Trial name
- NCT06249295
- Testing
- oral cryotherapy
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Pain, Postoperative
Liposomal Bupivacaine vs Standard Bupivacaine for Post-Rhinoplasty Analgesia
The purpose of this study is to find out which pain medication is more effective in reducing pain after nose surgery (rhinoplasty).
- Trial name
- NCT07689162
- Testing
- Standard Bupivacaine, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Washington University School of Medicine
Progressive Supranuclear Palsy, PSP
AMX0035 and Progressive Supranuclear Palsy
A35-009 (ORION) is a Phase 2b/3 trial to evaluate the efficacy and safety of AMX0035 in participants with Progressive Supranuclear Palsy (PSP), consisting of randomized, double blind placebo controlled phases, followed by an…
- Conditions
- Progressive Supranuclear Palsy, PSP, Neurodegenerative Diseases, Atypical Parkinsonism
- Trial name
- ORION (NCT06122662)
- Testing
- AMX0035
- Where
- 62 sites in United States, France and 3 more
- Volunteers
- 139 people
- Sponsor
- Amylyx Pharmaceuticals Inc.
Shoulder Pain, Chronic Pain
Feasibility of Near-infrared Spectroscopy to Measure Cortical Pain Pathway (Brain) Activation During Dry Needling
The benefit experienced by some patients when treated with dry needling,1 combined with the field-expedient nature of this intervention, make dry needling uniquely suited for the military healthcare environment.
- Conditions
- Shoulder Pain, Chronic Pain, Musculoskeletal Injury
- Trial name
- NCT04170803
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Army-Baylor University Doctoral Program in Physical Therapy
Newborn
The Effect of White Noise and Pacifier Applications on Pain and Crying Time
The objective of the study was to determine the effect of white noise and pacifier applications on pain and crying time in newborns during painful interventions. The research was planned experimentally.
- Trial name
- NCT06535061
- Testing
- white noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanko University
Stable Angina, Unstable Angina
Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study
The role of lipids as risk factors for cardiovascular events is well-documented, although events studied have largely been broad classes without specific detail. This study will examine a more refined set of endpoints.
- Conditions
- Stable Angina, Unstable Angina, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- NCT01687686
- Where
- United Kingdom
- Volunteers
- 175,872 people
- Sponsor
- University College, London
Hip Fractures, Anesthesia Local
Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block
The main objective of the trial is to complete a double-blinded randomized controlled trial with crossover design of a lumbosacral plexus block with the Suprasacral Parallel Shift technique guided by ultrasound/magnetic resonance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Perioperative
- Trial name
- NCT02593370
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Thomas F. Bendtsen
Pain
To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery
The objective of this study is to evaluate the safety and efficacy of acetaminophen 650 mg and acetaminophen 1000 mg in dental surgery.
- Trial name
- NCT01115673
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Retinal Disease, Age-Related Macular Degeneration
Stem Cell Ophthalmology Treatment Study II
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease.
- Conditions
- Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease
- Trial name
- SCOTS2 (NCT03011541)
- Testing
- Arm 1
- Where
- 4 sites in United States, Austria and 1 more
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Anxiety, Pain
Music Use in Parturients Admitted to Labor & Delivery
The goal of this clinical trial is to learn if music use affects anxiety or pain levels in parturients admitted to labor and delivery. It will also learn about the effect of music use on patient satisfaction.
- Conditions
- Anxiety, Pain, Patient Satisfaction
- Trial name
- NCT06969105
- Testing
- Music
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Advanced Parkinson's Disease
Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects
The primary objective of this study was to demonstrate the superiority of levodopa - carbidopa intestinal gel over treatment with optimized oral levodopa/carbidopa during 12 weeks.
- Trial name
- NCT00357994
- Testing
- Levodopa carbidopa intestinal gel (LCIG), Levodopa carbidopa (LC) oral encapsulated immediate release (IR) tablets, CADD-Legacy® 1400 ambulatory infusion pump
- Where
- 15 sites in United States, Germany
- Volunteers
- 36 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Pain Management
The Efficacy of Thoracoabdominal Nerve Block With Serratus Intercostal Plane and Rectus Sheath Block in Cholecystectomy
Cholecystectomy is a widespread surgical procedure performed worldwide for acute cholecystitis. This operation can be performed using open surgery or laparoscopic techniques.
- Trial name
- NCT06241794
- Testing
- Group M-TAPA, Group Serratus Intercostal Plane Block and Rectus Sheath Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hitit University
Coronary Artery Disease, Ischemic Heart Disease
Coronary and Structural Interventions Ulm - Bioresorbable Vascular Scaffold
To evaluate the safety, performance and efficacy of the bioresorbable vascular scaffold (BVS) system in patients with coronary artery disease
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Stable Angina, Unstable Angina
- Trial name
- CSI-Ulm-BVS (NCT02162056)
- Testing
- use of bioresorbable vascular scaffolds
- Where
- Germany
- Volunteers
- 326 people
- Sponsor
- University of Ulm
Pain Management, Posterior Spinal Fusion
Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery
This study consisted of a randomized controlled trial designed to evaluate a Multimodal Analgesia (MMA) Protocol on patients undergoing Posterior Spinal Fusion.
- Trial name
- NCT05413902
- Testing
- Toradol, Morphine, Orphenadrine
- Where
- Puerto Rico
- Volunteers
- 100 people
- Sponsor
- University of Puerto Rico
Lower Back Pain
Post Isometric Relaxation and Core Stability Exercises in Sacroiliac Joint Dysfunction
There is growing evidence on the effects of post isometric relaxation exercises and core stability exercises on pain and disability secondary to various disorders.
- Trial name
- NCT05529602
- Testing
- conventional physical therapy, relaxation exercise
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Rotator Cuff Tendinosis, Rotator Cuff Injuries
Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL)
The aim of this study will be to compare the effectiveness of an exercise therapy program with extracorporeal shockwave therapy, ultrasound-guided percutaneous irrigation and a wait and see approach in people with rotator cuff…
- Conditions
- Rotator Cuff Tendinosis, Rotator Cuff Injuries, Shoulder Tendinitis, Calcific Shoulder Tendinitis
- Trial name
- EFFECT (NCT05478902)
- Testing
- Exercise Therapy, Extracorporeal Shockwave Therapy, Ultrasound-Guided Percutaneous Irrigation
- Where
- 2 sites in Spain
- Volunteers
- 116 people
- Sponsor
- University of Valencia
Breast Cancer Female, Pain, Postoperative
Pectoral Nerve Block During Mastectomy
Impact of pectoral nerve block on postoperative pain and quality of recovery in patients undergoing breast cancer surgery: A prospective study
- Trial name
- PNB (NCT05699902)
- Testing
- PECs block during mastectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
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