Clinical trials: Neurologic Findings
Pain, Osteopathia
The Thrust Technique of Tibiotarsal Joint on the Symptomatology of Pain at Classical Ballet Dancers
Classical ballet is a type of high performance dance that requires great effort and extreme joint positions by its dancers, not to mention a precise control of the ankle joint when on pointe position.
- Conditions
- Pain, Osteopathia, Ankle Injuries
- Trial name
- NCT04512651
- Testing
- Tibiotarsal Thrust Manipulation, Simulation Tibiotarsal Thrust Manipulation
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do PiauÍ
Chronic Pain
Real-World Registry Study on Clinical Analgesic Effect of Acetylaconitine Tablets
1. To observe the clinical analgesic effect, safety and adverse reactions of acetylaconitine. 2. To study and analyze the main influencing factors of the acetylaconitine tablets.
- Trial name
- NCT05687929
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Ke Ma
Pain
Pain Relief at Iliac Crest Bone Harvest Sites in Spine Surgery Using Bupivacaine
The use of iliac crest bone graft (ICBG) remains the gold-standard in spinal reconstructive surgery for achieving fusion. Major complications from the harvesting of ICBG are rare, but chronic pain has been reported in 10-39%.
- Trial name
- NCT01087931
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University
Spondylitis, Ankylosing, Pain
An Efficacy and Safety Study of Tramadol/Acetaminophen Versus Diclofenac in the Treatment of Pain in Participants With Ankylosing Spondylitis Receiving Stable Treatment of Disease Modifying Anti-rheumatic Drugs (DMARDs)
The purpose of the study is to investigate the clinical benefit of tramadol/acetaminophen versus non-steroidal anti-inflammatory drugs (NSAID) (diclofenac 50 milligram [mg]) in the treatment of pain in participants with…
- Trial name
- NCT00766402
- Testing
- Tramadol /acetaminophen, Diclofenac
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Postherpetic Neuralgia
Involvement of Reorganization of Cerebral Functional Connectivity in the Process of Transition to Postherpetic Neuralgia
Postherpetic neuralgia(PHN) is a chronic neuropathic pain syndrome which persists more than 3 months after the resolution of the acute shingles episode.
- Trial name
- NCT03106896
- Volunteers
- 75 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Piriformis Syndrome
Effects of MET and MFR on Piriformis Syndrome
The aim of this study is to comparatively evaluate the effects of two different manual therapy approaches, Muscle Energy Technique (MET) and Myofascial Release Technique (MFR), on pain threshold, muscle activation patterns, and…
- Trial name
- NCT07769203
- Testing
- Muscle Energy Technique, Myofascial Release Technique, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Igdir University
Stellate Ganglion Block
Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients
Delirium is a common complication in elderly intensive care unit (ICU) patients and is associated with poor clinical outcomes. Circadian rhythm disruption is considered an important contributing factor in delirium development.
- Trial name
- NCT07558642
- Testing
- stellate ganglion block with 0.5% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Antalya Training and Research Hospital
Labor Pain
Intravenous Remifentanil for Labor Analgesia
Labor analgesia is an essential health caring procedure for women. However, epidural analgesia cannot be performed on all subjects for different contraindications, such as lower platelet counter, back infection at the puncture…
- Trial name
- IRELAN (NCT00710086)
- Testing
- Hydromorphone, Remifentanil
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing Medical University
Dry Eye Syndromes, Meige Syndrome
Wumeiwan Jiawei Fang Use in Patients With Blepharospasm
To evaluate the efficacy and safety of Jing Fang Wu Mei Wan Jiawei Fang in the treatment of idiopathic blepharospasm using a clinical randomized controlled trial method.
- Conditions
- Dry Eye Syndromes, Meige Syndrome, Blepharospasm, Hyperactivity
- Trial name
- NCT05618470
- Testing
- Wumeiwan Jiawei Fang, botulinum toxin A
- Where
- China
- Volunteers
- 80 people
- Sponsor
- China Academy of Chinese Medical Sciences
Knee Osteoarthritis
Knee Arthroplasty Pain Coping Skills Training (KASTPain): A Randomized Trial
Patients undergoing knee replacement surgery and who have high levels of pain catastrophizing are at risk for poor outcome. The clinical trial is designed to determine if a pain coping skills training intervention delivered by…
- Trial name
- KASTPain (NCT01620983)
- Testing
- Pain Coping Skills Training, Arthritis Education, Usual Care
- Where
- 5 sites in United States
- Volunteers
- 402 people
- Sponsor
- Virginia Commonwealth University
Postoperative Pain, Acute
Pulsed Shortwave Therapy for Postoperative Analgesia
Pulsed shortwave (radiofrequency) therapy is a possible method of pain control involving the application of electromagnetic energy (also termed pulsed electromagnetic fields).
- Trial name
- NCT05796583
- Testing
- Active Pulsed Shortwave Treatment
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Breast Cancer Surgery, Post Operative Pain
The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Breast cancer is a devastating disease. Some women with breast cancer undergo surgery to remove the breast and lymph nodes in the axilla (armpit).
- Trial name
- NCT00852683
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Nova Scotia Health Authority
Pain, Stress
Pain and Stress Assessment and ROP Screening
The study will measure the effects of eye exams on markers of stress in the urine. In addition, measurements will be taken to show the effects of stress on brain activity, O2 sats, and blood flow.
- Trial name
- NCT02415205
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Shoulder Pain
Neuroscience Education in Shoulder Pain: Clinical Trial
Objectives: The purpose of this study was to assess the efficacy of a pain neuroscience education programme applied to patients with shoulder pain.
- Trial name
- NCT06739694
- Testing
- PNE, Manual therapy
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Universidad de León
Tendonitis of the Shoulder, Elbow, or Knee
A Pilot Study on the Onset of Action of KTP, 20% in the Treatment of Acute Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee
Open-label study to be conducted at 2 US investigational sites in subjects who have acute tendonitis or bursitis of the shoulder, elbow, or knee.
- Trial name
- KTP (NCT00903994)
- Testing
- Ketoprofen Topical Patch 20%
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- APR Applied Pharma Research s.a.
Attention Deficit Disorder, Sleep Initiation and Maintenance Disorders
Better Sleep in Psychiatric Care - ADHD Pilot Study
Comorbidities, including sleep problems, are common in adult Attention Deficit Hyperactivity Disorder (ADHD). Treatment of choice for insomnia is cognitive behavioral therapy (CBT-i), but evidence is lacking for CBT-i in patients…
- Conditions
- Attention Deficit Disorder, Sleep Initiation and Maintenance Disorders, Sleep Wake Disorders
- Trial name
- BeSiP-ADHD (NCT03852966)
- Testing
- CBT-i/ADHD
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Karolinska Institutet
Posterior Fossa Tumor
Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery.
The goal of this clinical trial is to evaluate the effects of ultrasound-guided versus blind greater occipital nerve block (GONB), with or without Dexmedetomidine as an adjuvant, in pediatric patients undergoing posterior fossa…
- Trial name
- NCT07878156
- Testing
- Bupivacaine 0.25%, Dexmedetomidine 1mcg/kg, Blind greater occipital nerve block
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Chronic Pain, Hemophilia
Chronic Pain and Hemophilia
Hemophilia (A and B) are X-linked hereditary bleeding disorders whose severity depends on the level of coagulation factor (FVIII or FIX respectively). Bleeding is mainly from joints (hemarthrosis) and muscles (hematoma).
- Trial name
- HEMODOL (NCT05202951)
- Testing
- questionnaires
- Where
- 10 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anxiety, Depression
A Feasibility Study of a Guided Self-help Programme for Male Offenders Serving a Long-term Prison Sentence
Background: Prisoners have complex mental health needs, and there is a disproportionately higher incidence of mental health problems compared with the general population.
- Trial name
- NCT04746651
- Testing
- Guided Self Help
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure
Irrigation Fluid Volume, Tube Cuff Pressure, and Neck Swelling During Shoulder Arthroscopy
During shoulder arthroscopy, fluid is pumped into the shoulder to help the surgeon see inside the joint. Some of this fluid can move into the tissues around the shoulder and neck and cause swelling.
- Conditions
- Shoulder Arthroscopy, Endotracheal Tube Cuff Pressure, Neck Soft Tissue Edema
- Trial name
- NCT07852702
- Testing
- Elective Shoulder Arthroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
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