Clinical trials: Neurologic Gait Disorder
Stroke
Automated Trainer-Based Gait Rehabilitation for Hemiplegic Stroke Patients
This study aims to evaluate the effectiveness of an automated mobile gait training device developed based on neurodevelopmental treatment (NDT) principles for patients with hemiplegic stroke.
- Trial name
- NCT07411703
- Testing
- NDT Gait Training System
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Cheng-Hsin General Hospital
Parkinson's Disease, Movement Disorders
Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients
The goal of this clinical trial is to explore the effects of cerebellar nuclei TIS stimulation on improving tremor and gait disorders in PD patients.
- Trial name
- NCT07384442
- Testing
- Real Temporal Interference Stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- YangPan
Parkinson's Disease, Essential Tremor
Movement Disorder Quantification Algorithm Development
The purpose of this study is to collect kinematic motion data from subjects with movement disorders such as Parkinson's disease (PD) and essential tremor (ET) to develop and validate algorithms for quantifying motor symptoms such…
- Trial name
- NCT01534650
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Cerebral Palsy, Gait Disorders
The Effects of Exoskeletal Robot-Assisted Gait Training on Children With Cerebral Palsy: A Pilot Study
Cerebral Palsy (CP) is a complex neurodevelopmental disorder caused by early brain injury, leading to motor impairments such as muscle weakness, stiffness, and gait instability, which impact daily functioning.
- Conditions
- Cerebral Palsy, Gait Disorders, Gait Disorders in Children, Gait Disorders, Neurologic
- Trial name
- NCT05759182
- Testing
- Powered Exoskeleton Gait Training
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment
Vibration Effects on Gait and Balance in CP
This randomized controlled study aims to investigate the acute effects of local vibration applied to the spastic medial gastrocnemius muscle on balance and spatiotemporal gait parameters in children with hemiparetic cerebral…
- Trial name
- NCT07045519
- Testing
- Local Vibration Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kırıkkale University
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Plus Finasteride Treatment After Spinal Cord Injury
The purpose of this study is to determine whether testosterone plus finasteride treatment will improve musculoskeletal health, neuromuscular function, body composition, and metabolic health in hypogonadal men who have experienced…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injuries
- Trial name
- NCT02248701
- Testing
- Testosterone Enanthate, Finasteride
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Virtual Reality; Rehabilitation; Parkinson's Disease
Virtual Reality-based Interactive Treadmill Gait Training System for Parkinson's Disease
Virtual-reality-based interactive treadmill system will be applied to the Parkinsons' disease patients who can walk (Hoehn and Yahr stage 2 to 4).
- Trial name
- NCT03686462
- Testing
- Virtual reality-based interactive treadmill training, Treadmill training without VR-based interaction
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital
Parkinson Disease
Neural and Kinematic Features of Freezing of Gait for Adaptive Neurostimulation
Continuous deep brain stimulation (cDBS) is an established therapy for the major motor signs in Parkinson's disease, however some patients find that it does not adequately treat their freezing of gait (FOG).
- Trial name
- NCT03180515
- Testing
- Activa PC+S Neurostimulator
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Stroke
Visuo-Vestibular VR-based Stimulation Effects on Balance and Gait in Stroke Survivors
This pilot study aims to evaluate the effect of a specfic Virtual-Reality-Based rehabilitation training in patients with stroke.
- Trial name
- NCT06780488
- Testing
- Real Visual-Vestibuar Rehabilitation
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Parkinson Disease
Effects of Virtual Reality and Otago Exercises in Parkinson's Disease Patients.
Parkinson's disease, the second most common neurological condition, significantly affects motor function, gait, balance, and daily living activities.
- Trial name
- NCT06838741
- Testing
- otago exercises, virtual reality
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
Gait Disorders, Neurologic
The Effect of a Wearable Cueing Device on Freezing of Gait in Parkinson's Disease
The CuePeD trial is an intervention trial measuring the effectiveness of a novel treatment for Freezing of Gait (FOG) in Parkinson's disease (PD).
- Trial name
- CuePed (NCT02356536)
- Testing
- Agilitas
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- The University of Queensland
Gait Disorders, Neurologic, Stroke
Effect of Gait Training With a Walking Assist Robot on Gait Function and Balance in Patients With Chronic Stroke
The purpose of this study was to investigate the effects of gait training with the new wearable hip assist robot developed by Samsung Advance Institute of Technology (Samsung Electronics Co, Ltd, Korea) in patients with chronic…
- Trial name
- NCT03326011
- Testing
- Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Samsung Medical Center
Parkinson Disease (PD)
Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease
Freezing-of-gait (FoG) in Parkinson Disease (PD) is one of the most vivid and disturbing gait phenomena in neurology. Often described by patients as a feeling of "feet getting glued to the floor," FoG is formally defined as a…
- Trial name
- XF (NCT06602544)
- Testing
- Robotic Apparel
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Gait Analysis in Neurological Disorders
Investigation of Gait Parameters in Health and Neurological Disease Under Varying Locomotor Conditions
In the cross-sectional component of this study, our overall objective is to gather a large pool of data from which we can generate gait "profiles".
- Trial name
- NCT02165787
- Where
- Switzerland
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Balance, Gait Analysis
Effectiveness of Dance Therapy in Stroke Patients.
Hemiparesis following a stroke is associated with persistent deficits in postural control, balance, and social participation, especially in the chronic phase.
- Conditions
- Balance, Gait Analysis, Thermography, Range of Motion, Articular
- Trial name
- NCT07578493
- Testing
- Dance therapy, Regular physiotherapy
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- University of Salamanca
Multiple Sclerosis
Effectiveness of Dry Needling for Improving Gait in the Patient With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease characterized by the appearance of lesions, characterized by heterogeneity in its pathological, clinical and radiological presentation.
- Trial name
- DRYNEEDEM (NCT05956119)
- Testing
- dry needling + physiotherapy (standard/usual care)
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Hospital Universitario de Canarias
Gait, Hemiplegic, Stroke
Innovative Biofeedback Interface for Enhancing Stroke Gait Rehabilitation
This study will conduct a preliminary evaluation of and obtain user data on a novel game-based visual interface for stroke gait training.
- Trial name
- NCT04013971
- Testing
- AGRF Biofeedback Game, Traditional Biofeedback Interface, Control Condition
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke, Robotic Rehabilitation
Effects of Robotic-Assisted Gait Training in Patients With Stroke (EoRAGTiPwS)
This study was conducted to examine effects of gait training with exoskeleton ExoAthlet and Lokomat Free-D on functional independence, functional capacity and quality of life in stroke patients.
- Trial name
- EoRAGTiPwS (NCT05937464)
- Testing
- Exoskeleton ExoAthlet group, Lokomat Free-D group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Antalya Bilim University
Foot Drop, Peripheral Nervous System Diseases
Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project
The purpose of this research study is to test the utility of an ankle robot, when used during treadmill walking, in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or…
- Conditions
- Foot Drop, Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Mobility Limitation
- Trial name
- NCT03556709
- Testing
- Treadmill Ankle Robot Training
- Volunteers
- 100 people
- Sponsor
- Baltimore VA Medical Center
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