Clinical trials: Neurological; Disorder, Nervous System
Shoulder Pain
Determining the Minimal Effective Volume (MEAV95) for Interscalene Brachial Plexus Block for Surgical Anesthesia
Interscalene block (ISB) consistently demonstrates superior pain relief after shoulder surgery. However, patients can experience complications such as blurred vision, hoarseness and shortness of breath with the standard volumes…
- Trial name
- MEAV 95 (NCT01703130)
- Testing
- Dose of of ropivacaine 0.75% used in block procedure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Trismus, Cancer
Efficiency of Different Treatment Modalities on Radiation Induced Trismus for Maxillofacial Patients
Aim: to compare different treatment modalities for radiation induced trismus for maxillofacial patients methods:45 participants (20 females and 25 males) with trismus and pain following head and neck cancer and underwent…
- Trial name
- NCT06413628
- Testing
- screw tapered appliance
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Bipolar Disorder, Bipolar Affective Psychosis
Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.
The primary purpose of the study is to assess the efficacy of Quetiapine extended release 600mg per day either as monotherapy or combined therapy in the treatment of patients with mania associated to Bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar Affective Psychosis, Mania, Manic Disorder
- Trial name
- EMMY (NCT00521365)
- Testing
- Quetiapine 600mg
- Where
- 7 sites in Mexico
- Volunteers
- 88 people
- Sponsor
- AstraZeneca
Tetraplegia
Electrical Stimulation in Denervated Muscles of the Upper Limbs
In the last decade the stimulation of denervated muscles got more attention. Not at least because of the promising results of the RISE project (Use of electrical stimulation to restore standing in paraplegics with long-term…
- Trial name
- NCT03698136
- Testing
- Stimulation of denervated muscles
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Psychomotor Retardation, Psychomotor Slowing
Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders
Psychomotor slowing may occur in major psychiatric disorders, such as major depressive disorders or schizophrenia spectrum disorders. It refers to slowing of fine motor skills, motor planning and gross motor behavior.
- Conditions
- Psychomotor Retardation, Psychomotor Slowing, Schizophrenia and Related Disorders, Major Depressive Disorder
- Trial name
- NCT03275766
- Testing
- DLPFC facilitatory, SMA inhibitory, SMA facilitatory
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Bern
Deafness
Novel Coding Strategies for Children With Cochlear Implants
The purpose of this study is to understand performance with a cochlear implant. The long-term goals of this research are to improve sound perception with cochlear implants and to better understand the functioning of the auditory…
- Trial name
- NCT05203302
- Testing
- Single-Electrode Pulse Train, Modulation Detection Threshold (MDT) and Gap Detection Tasks, Sound coding strategy.
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Spinocerebellar Ataxia Type 2
Study of ARO-ATXN2 Injection in Adults With Spinocerebellar Ataxia Type 2
Adult participants with spinocerebellar ataxia type 2 (SCA2) who carry ≥33 cytosine, adenine, guanine (CAG) repeats in the ATXN2 gene, and who have met all protocol eligibility criteria will be randomized to receive a single dose…
- Trial name
- NCT06672445
- Testing
- ARO-ATXN2 Injection
- Where
- 16 sites in Australia, Canada and 6 more
- Volunteers
- 39 people
- Sponsor
- Arrowhead Pharmaceuticals
Stroke, Weakness, Muscle
EMG Training for Altering Activation Patterns After Stroke
Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.
- Conditions
- Stroke, Weakness, Muscle, Coordination Lack
- Trial name
- NCT03619772
- Testing
- Bilateral, Unilateral
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
The Effectiveness of Novel Rehabilitation Device on Upper Limb Impairment Among Patients With Stroke
Usability and Effectiveness of a Novel Bilateral Upper Limb Training Device for Stroke Patients With Hemiparesis: A Preliminary Study
Background and Study Aims Stroke is a leading cause of long-term disability worldwide, affecting millions of individuals each year.
- Trial name
- Synslai (NCT06956677)
- Testing
- Novel UE rehabilitation device training, The UE functional training, Conventional occupational therapy
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- Chang Gung Memorial Hospital
Urolithiasis
Music During ESWL for Entire Treatment
The aim of this study is to evaluate if music listening relieves pain and discomfort during Extracorporeal Shock-Waves Lithotripsy (ESWL).
- Trial name
- NCT04380675
- Testing
- Music
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Fibromyalgia
Comparative Study About the Effect of Aquatic Therapy vs Land-based Therapy in Women With Fibromyalgia
Fibromyalgia is a disease whose incidence rate is increasing and causing a severe disability to those who suffer it. Currently, other treatment resources are being implemented, such as aquatic therapy.
- Trial name
- NCT02695875
- Testing
- Aquatic therapy, Land-based therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidade da Coruña
Rheumatic Diseases, Arthritis
Pain-Sleep in Rheumatic Disease
Overall, our understanding of how pain and sleep are experienced and how they can be treated in teenagers with rheumatic diseases is limited.
- Conditions
- Rheumatic Diseases, Arthritis, Lupus, Lupus Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07775612
- Testing
- Better Nights, Better Days for Youth
- Volunteers
- 43 people
- Sponsor
- The Hospital for Sick Children
Paraplegia, Spinal Cord Injury
Personal Exoskeleton or Manual Wheelchair: a Comparison of Performance and Satisfaction in Activities of Daily Living Among People With Spinal Cord Injuries, Using the SCED Methodology.
Spinal cord injuries resulting in paraplegia affect patients' mobility and, consequently, their ability to participate in activities of daily living.
- Trial name
- KER-EXHOME (NCT07828912)
- Testing
- Carrying out tasks using the EVE exoskeleton and a manual wheelchair.
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Hearing Loss
Collection and Characterization of Objective Measures to Explore the Specificity of Algorithms
The aim of this descriptive study is to collect and describe the characteristics of objective measures to explore the specificity of algorithms.
- Trial name
- NCT03294681
- Testing
- Objective measures with CSEP
- Where
- 6 sites in Australia, Germany and 1 more
- Volunteers
- 153 people
- Sponsor
- Cochlear
Alzheimer's Disease
Memantine for Agitation and Aggression in Severe Alzheimer's Disease
Alzheimer's disease (AD) is the most common form of dementia and is characterized by both cognitive and behavioural symptoms ("Behavioural and Psychological Symptoms of Dementia"; BPSD).
- Trial name
- NCT00401167
- Testing
- memantine
- Where
- 2 sites in Canada
- Volunteers
- 31 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cancer
The Effect of Sujok Therapy on Cancer Symptoms
The aim of this study is to determine the effect of Sujok therapy on Pain, Fatigue, Insomnia, Nausea and Vomiting experienced by patients with gastrointestinal system cancer.
- Trial name
- NCT05265754
- Testing
- sujok therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Ataturk University
Headache, Headache Disorders
Cross-cultural Adaptation, Reliability and Validity of the Turkish Version of the Headache Disability Questionnaire
The purpose of this study was to investigate cultural adaptation, reliability and validity of the Turkish version of the Headache Disability Questionnaire (HDQ).
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Headache, Tension
- Trial name
- NCT04736654
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Gazi University
Sarcopenia in Elderly
Tai Chi Exercise to Improve Quality of Life and Depression in Elderly With Sarcopenia
This study aims to evaluate the effects of Tai Chi exercise on quality of life and depressive symptoms in elderly with sarcopenia.
- Trial name
- NCT07831356
- Testing
- Tai Chi Exercise, Elderly exercise (senam lansia)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency
Correlation of Radiological Lesions With Vestibular Function in Patients With Bilateral Vestibulopathy
In 2014 radiologic lesions were detected at one or more semicircular canals using CT and MR imaging of temporal bone in subjects carrying the p.P51S mutation in COCH.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency, DFNA9, Radiology
- Trial name
- NCT04070937
- Testing
- vestibular test 1, vestibular test 2, vestibular evoked myogenic potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Jessa Hospital
Vision Disorders
Study of A New Contact Lens Cleaning and Disinfecting Solution
The objective of this study is to evaluate the safety and efficacy of a new investigational cleaning and disinfecting solution (Test) compared to Clear Care cleaning and disinfecting solution (Control) when used by contact lens…
- Trial name
- NCT01318577
- Testing
- Investigational Cleaning & Disinfecting Solution, Clear Care Solution
- Where
- United States
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
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