Clinical trials: Neurological Condition
Pain
Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders
Joints and muscles disorders are common symptoms in the population. They are characterized by swelling, pain, functional impairment and morning stiffness.
- Trial name
- Easykrill (NCT02318875)
- Testing
- Kritech administration
- Where
- France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vivatech
Gastroparesis, Diabetes Mellitus
Effects of Sitagliptin on Gastric Emptying in Healthy Subjects
The purpose of this study is to determine the effects of the drug, sitagliptin, on the rate at which the stomach empties, and the release of gut hormones and blood glucose concentrations, after a mashed potato meal in healthy…
- Trial name
- NCT00501657
- Testing
- Sitagliptin
- Where
- Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Chronic Pain, Postoperative, Quality of Life
Quality of Life and Pain After Appendectomy in Children
Acute appendicitis is one of the most common emergency general surgical conditions worldwide and represents the leading cause of emergency abdominal surgery in children.
- Conditions
- Chronic Pain, Postoperative, Quality of Life, Functional Ability, Appendectomy
- Trial name
- CAPA-Peds (NCT07629362)
- Where
- Turkey (Türkiye)
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Health Impairment, Pain
High School Football and Adult Health
The primary aim of the study is to determine the effect of playing high school football on self-rated health in late adulthood. This is an observational study that will use data from the Wisconsin Longitudinal Study, a…
- Conditions
- Health Impairment, Pain, Obesity
- Trial name
- NCT03914573
- Where
- 2 sites in United States
- Volunteers
- 3,355 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Lesional Coma
Imaging of the Neural Correlates of Arousal and Awareness
In last decades, several advances in the neuro-intensive management have lead to decrease mortality in Intensive Care Units. A significant morbidity remains as patients survive after a traumatic coma with uncertain quality of…
- Trial name
- IMAGINA (NCT04575454)
- Testing
- Multimodal evaluation of brain function : PET-MRI, electrophysiology, eye-tracking
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Congenital Heart Defects, Down Syndrome
Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD
Congenital heart diseases (CHD) are detected in 40-60% of individuals with Down syndrome (DS) and increase the risk of developmental delay in the presence of syndromes.
- Conditions
- Congenital Heart Defects, Down Syndrome, Gross Motor Development Delay
- Trial name
- NCT05191654
- Testing
- evaluation of cardiopulmonary parameters, gross motor development and hand grip strength
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Atılım University
Anxiety, Cesarean Section Complications
The Effect of Pre-operative Videotape Before a Planned Cesarean Section on Anxiety Level
The study aim is to examine the relationship between providing information to women prior to elective cesarean delivery and anxiety levels around surgery. the patients will be assigned into two groups - intervention and control.
- Conditions
- Anxiety, Cesarean Section Complications, Pain, Postoperative, Analgesia
- Trial name
- NCT04177966
- Testing
- pre-prepared video describing the cesarean surgery, general information
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Relative Afferent Pupil Defect (RAPD)
Measuring Relative Afferent Pupillary Defect
The goal of this prospective reliability study is to test the effectiveness of a commercially available, off-the-shelf virtual reality head-mounted display (VR HMD) and machine learning (ML) algorithms in detecting Relative…
- Trial name
- RAPD (NCT05799066)
- Testing
- Swinging Light test, Virtual Reality Head-Mounted Display (VR HMD)
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Miscarriage
Virtual Reality in MVA for Miscarriage
We are investigating the use of a virtual reality programme to reduce pain and anxiety experienced during manual vacuum aspiration.
- Trial name
- NCT04466956
- Testing
- Virtual reality
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Muscle Injury, Muscle Atrophy
Ultrasound Measurements Hamstring Muscles Thickness
No previous studies have compared the association between muscle thickness (MT) and muscle cross-sectional area (CSA) in healthy volunteers.
- Trial name
- NCT02958254
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Valencia
Pain Management
Comparing the Effectiveness of Hyalone and Calcium Hydroxide in Reducing Post-operative Pain and Promoting Periapical Healing.
This protocol presents a randomized clinical trial comparing Hyalone (hyaluronic acid) with calcium hydroxide as intracanal medicaments in mandibular first molars with necrotic pulp and symptomatic apical periodontitis.
- Trial name
- HCPH (NCT07821866)
- Testing
- Hyalone, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Anemia, Constipation
Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron.
Oral iron supplementation is often associated with rapid onset of gastrointestinal side-effects. The aim of this study was to develop and trial a short, simple questionnaire to capture these early side-effects and to determine…
- Conditions
- Anemia, Constipation, Diarrhea, Abdominal Pain
- Trial name
- NCT02146053
- Testing
- ferrous sulfate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical Research Council
Pain, Acute
Water-friendly Virtual Reality and Brief Thermal Pain
Using immersive virtual reality as a form of pain distraction during a brief "painful but tolerable" temperature.
- Trial name
- NCT04245475
- Testing
- Virtual Reality psychological pain reduction
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Washington
Shoulder Pain
Influence of Anthropometric Data, Shoulder Complex Muscle Strength, and Abdominal-lumbar Endurance in Closed Kinetic Chain Upper Extremity Stability Test
A previous study of the Closed Kinetic Chain Upper Extremity Stability Test (EPOLTEST) in a population aged 18 to 25 years isolated 3 main factors influencing the CKCUEST score: upper extremity span, weight, and sex of the…
- Trial name
- EPOLTEST 2 (NCT05291273)
- Testing
- Closed Kinetic Chain Upper Extremity Stability Test, Prone Bridge Test, Measurement of the muscle strength of the shoulder complex
- Where
- France
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Pain
The Effect of Dance and Massage Applied by Partners at Birth on Birth Pain, Comfort and Satisfaction
Pregnancy and the moment of birth are important processes that women will remember throughout their lives and will always leave a mark on their lives.
- Trial name
- NCT06179966
- Testing
- Dance group, Massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Piriformis Syndrome
Effects of Soft Tissue Mobilization Technique and Piriformis Muscle Stretching Among Patients Having Piriformis Syndrome
It is a randomized control trail in which soft tissue mobilization and piriformis stretching will be compared and study duration will be of five months
- Trial name
- NCT05680402
- Testing
- Soft Tissue mobilization, Piriformis Syndrome (Piriformis muscle stretching)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Stroke, Hemiplegia
Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Brain on the Neurotransmitter Binding
The purpose of this study is to determine whether repetitive transcranial magnetic stimulation (rTMS) over the brain can modulate the binding of neurotransmitter (GABA in this study) to its receptor using the special PET study.
- Trial name
- NCT01819675
- Testing
- Low frequency rTMS, High frequency rTMS
- Where
- South Korea
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Pain, Postoperative, Opioid Use
Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy
This is proof of concept, phase I randomized controlled trial studying a short acting non-opioid anesthetic, bupivacaine to improve post-operative pain in gynecologic surgery patients.
- Trial name
- NCT04157075
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Mania
Neurochemical Effects of Omega-3 Fatty Acids in Adolescents at Risk for Mania
The purpose of this study is to see if taking a substance called omega-3 fatty acids is effective, safe, and well-tolerated for treating adolescents with major depressive disorder (also called simply "depression" or "clinical…
- Trial name
- R34 (NCT00917501)
- Testing
- OMega 3
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Surgery, Laparoscopic
Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery.
- Conditions
- Surgery, Laparoscopic, Laparoscopy, Penumoperitoneum
- Trial name
- NCT06504277
- Testing
- Low Pressure Penumoperitoneum, Standard Pressure Group (No intervention- active comparator)
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
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